Gene Information

Name : Mesil_0096 (Mesil_0096)
Accession : YP_003683549.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : -
Position : 98375 - 98860 bp
Length : 486 bp
Strand : -
Note : COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796:IPR012259:IPR017925; KEGG: tau:Tola_2373 dihydrofolate reductase; PFAM: dihydrofolate reductase region; PRIAM: Dihydrofolate reductase; SPTR: C1XRX8 Dihydrofolate reductase; PFAM: Dihydrofolate red

DNA sequence :
ATGGATAGCCCTTCCCTCACCCTTATCGCCGCCATGGACCGCAACCGCGCCATCGGCAAGGGGGGTCGGCTGCCCTGGCA
TCTCCCCGATGACCTGCGGCGCTTCAAGGCCCTCACCCTGGGCCATACCGTACTGATGGGCCGTAAGACCTTTGAGAGCA
TTGGGCGGCCCCTGCCGGGGCGCCGAAACGTGGTCCTGACCCGAAACCCCAACTTCCAAGCCGAGGGGGTCGAGGTGGTC
CCCACCCTCCAAGCAGGCCTGGCGGGCGGAGAGATCATGGTGATTGGCGGCGGGGAAGTCTATGCCCTCGCCCTTCCCCT
CGCCCGGCGAATGTGGCTGACCCTGGTGGATACCGAGATTACGGAGGCAGATACCTTTTTCCCCGAGTTCGACCCCTCCG
AGTGGAGGGAGACGGGCCGAGCCTTTCACCCCGCCGATGGGCAACATCCGTTCTCGTTCAGCTTCTTAGACCTCGAGCGA
CGCTAA

Protein sequence :
MDSPSLTLIAAMDRNRAIGKGGRLPWHLPDDLRRFKALTLGHTVLMGRKTFESIGRPLPGRRNVVLTRNPNFQAEGVEVV
PTLQAGLAGGEIMVIGGGEVYALALPLARRMWLTLVDTEITEADTFFPEFDPSEWRETGRAFHPADGQHPFSFSFLDLER
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 7e-21 44