Gene Information

Name : Mesil_0841 (Mesil_0841)
Accession : YP_003684262.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 834711 - 835382 bp
Length : 672 bp
Strand : -
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR011991:IPR011006:IPR 016032; KEGG: ttj:TTHA0145 phosphate regulon transcriptional regulatory protein PhoB; PF

DNA sequence :
ATGATGCCGAAGCTTCTGGTGGTCGAGGATGAGCCTGCCGTACGGATGGGCCTACGCCTATCCCTGAGCCGAGCCGGGCA
CCAAGTTCTGGAGGCCGCCACCGCCACCGAAGCCTGGGAGCAGCTGCCCCAGGCCGATCTGGTGGTACTGGACTGGATGT
TGCCCGACGAGCCGGGGGTACGGCTGTTGGAGCGCCTGCGCCGCGATGGTCGCTATGAGAACCTGCCGGTGCTGATGCTC
ACCGCGCGAGCCGGGGAGGGTGACCGAGTGGAAGGGCTCACCCGCGGGGCCGACGACTATTTAACCAAGCCCTTCTCGAC
CCCCGAACTCTTAGCCCGCATCCAGGCCTTACTGCGCCGCAGCGGGAAAAGCGGACGGATTGAGCGAGGTGGGCTAGCTT
TGGACCTCGAGCGCCACCAGGCCAGCCTGGATGGTCGGCCCCTCGACCTCACCCGGCGCGAGTTCGACCTGCTGGCCTTC
CTGGCCCGTCACCCAGGACGGGTCTACAGCCGCGAGGAGCTGCTCGAGCGGGTGTGGGGGCCAGAGTTCATGGGCACCGC
CCGCACCGTAGACCAGCACGTGGCACAACTGCGCGAGAAACTTCAGGAAGACCCCAAGCTGCCGCGCTTCCTCGAGACGC
TGCGCGGGGTGGGCTACCGCTTCAGGGAATAA

Protein sequence :
MMPKLLVVEDEPAVRMGLRLSLSRAGHQVLEAATATEAWEQLPQADLVVLDWMLPDEPGVRLLERLRRDGRYENLPVLML
TARAGEGDRVEGLTRGADDYLTKPFSTPELLARIQALLRRSGKSGRIERGGLALDLERHQASLDGRPLDLTRREFDLLAF
LARHPGRVYSREELLERVWGPEFMGTARTVDQHVAQLREKLQEDPKLPRFLETLRGVGYRFRE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 4e-35 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 5e-35 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator CP001918.1.gene5135. Protein 9e-24 45
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 1e-38 43
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 2e-42 43
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_002516.2.879194.p Protein 8e-28 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator CP001138.1.gene4273. Protein 2e-24 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator CP004022.1.gene3215. Protein 2e-27 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator BAC0083 Protein 2e-29 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator BAC0487 Protein 5e-25 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator CP000647.1.gene4257. Protein 2e-24 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator BAC0533 Protein 2e-24 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 1e-36 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 9e-37 41
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 9e-37 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator VFG1389 Protein 2e-29 44
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator VFG1390 Protein 6e-31 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator VFG1563 Protein 2e-35 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator VFG1702 Protein 2e-35 42
Mesil_0841 YP_003684262.1 winged helix family two component transcriptional regulator VFG0473 Protein 8e-26 41