Gene Information

Name : Mesil_0416 (Mesil_0416)
Accession : YP_003683864.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 422843 - 425410 bp
Length : 2568 bp
Strand : -
Note : COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176:IPR003959:IPR013093:IPR019489:IPR 018368:IPR001270:IPR017730:IPR003593; KEGG: tth:TTC1123 endopeptidase Clp ATP-binding chain B, ClpB; PFAM: ATPase AAA-2 domain protein; A

DNA sequence :
ATGAATCTCGAGGTCTGGACCGAACAAGCCCGGCAAGCCCTAGCACAAGCCCAGGTCTTGGCGCGTGAGTTTTCCCATCA
AGCCATCGACGTGCCGCACCTGGCCGCGGTGTTGTTAAAAGACCCCCAGGGCCTGCCCGCGCGGCTGGTGGGACGAGCCG
GCGGGAACCCCTCCTCCATCTACCAAGCGGCGCAAAGCGAGCTGGGGCGACTACCCAAGGTTTCCGGCAGCGAGGGTGGG
CAGTACCTTTCCAATCGGCTGAACGCGGTTTTTGACCGCGCCGAAGCCATCGCCAAAGAACTCGGCGATAAGTTCGTGGC
CGTAGACACCCTGACTTTGGCCTTAGCCGAGACCGGCTACGCTGGGCTGCCTAGCATCAGCGCGCTCCGGAGGGCCATTC
AGGAAATACGAGGAGGGAAGAAAGTGGACAGCGCAAACGCAGAGGGTACCTATCAAGCCCTCGAGCAGTACGGGCTTGAC
CTCACCGCCTTGGCCGAGCAAGGCAAGCTGGACCCGGTGATCGGGCGCGACGAGGAGATCCGCCGCACGGTGCAGATCCT
GCTGCGCCGGACCAAGAACAACCCGGTGCTCATCGGGGATCCCGGGGTGGGTAAGACCGCCATCGTGGAAGGGCTGGCCC
AGCGGATCGTCAAGGGCGACGTGCCCGAGGGGCTCAAGGGCAAGCGGATCATCTCGCTCCAGATGGGCTCCTTGCTGGCC
GGAGCCAAGTACCGCGGCGAGTTTGAGGAACGCATGAAGGCGGTGATTCAGGAAGCCATCCAGAGTGCAGGCGAGGTGAT
CCTGTTCGTGGATGAGCTGCACACCGTGGTGGGAGCGGGGAAAGCCGAGGGCGCGGTGGACGCCGGGAACATGCTCAAGC
CCGCGCTGGCCCGGGGCGAGTTGCACATGATCGGGGCGACCACCCTGGACGAGTACCGCGAGATCGAGAAAGATGCCGCC
CTCGAGCGCCGCTTCCAGCCCGTGTTCGTGGAAGAGCCCAGCGTGGAGGACACCATCTCCATCCTGCGCGGGATCAAGGA
GAAGTACGAGGTGCACCACGGGGTCAGAATCAGCGACCCGGCCATCGTGGCCGCGGCGGTACTCTCGCACCGCTATATCT
CCGACCGCAAACTCCCCGATAAGGCTATCGACCTCATCGACGAGGCGGCAGCCCGCATCCGCATGGCGCTGGAATCGAGC
CCGGAGCAGATCGACTCGCTCGAGCGCAAGAAGCTCCAACTGGAGATCGAGCGCCAGGCCTTGAAGAAGGAGACCGACCT
CGAGTCCAAGGCCCGGCTGGACGACATCGAGGCGGAGATCGCCAGCCTCAACGAGGAGATCGGCAAGCTCAAAACCGAGT
GGGAAGCCGAGCGCGAGGTGCTGAAGTCCTTGCGCGAAGCCCAGCAGCGCCTCGACGAGGTGCGCACCAGCATCGAACAG
GCCGAGCGGGCCTATGACCTCAACAAGGCCGCCGAGTTGCGCTATGGCGAACTGCCCCGGCTCGAGGCTCGGGTAAAGGA
ACTCTCCGAGCAGCTCAGGAACGCTAAGTTCGTCCGGCTGGAGGTCACCGAGGAGGATATCGCCCAGGTGGTCTCGCGCT
GGACCGGCATCCCGGTAGCCAAGCTGCTGGAGGGGGAACGCGAGAAGCTCCTCCGGCTGGAAGAAGAGATGCACAAACGG
GTGGTGGGCCAAGACGAGGCCATCGTTGCTGTAGCGGACGCCATCCGGCGAGCCAGGGCCGGCCTCAAAGACCCCAACCG
CCCCATCGGGAGCTTCCTCTTCCTGGGGCCTACCGGGGTGGGCAAGACCGAGCTGGCCAAAACCCTAGCGGCCCAGCTCT
TCGACACTGAAGAGAACATGGTGCGCATCGACATGTCGGAGTACCAGGAGAAGCACACTGTGGCCCGGCTGATCGGCGCG
CCTCCGGGATACGTGGGCTATGAGGAAGGCGGGCAGCTCACCGAAGCGGTGCGCCGCCGCCCCTACTCGGTGATTCTCTT
CGACGAGATTGAGAAGGCCCACCCCGACGTGTTCAATGTGCTGTTGCAGATCCTCGACGATGGGCGGCTCACCGACGGGC
AGGGGCGCACGGTGGACTTCCGCAACACAGTGATCATCCTGACCTCGAACCTGGGCTCGCCGCTGATCCTCGAGGGCATC
CAGGCGGGTCTTCCCTACGAGACCATCCGCAACCGGGTCTTCGAGGTCTTGCAGAAGAACTTCCGCCCCGAGTTCCTGAA
CCGTCTGGACGAGATTGTAGTGTTCAAACCGCTCACCCAGGAGCAGATCGCCCAGATCGTGGAGATCCAGCTCGAGGGCC
TGCGGCGTCGGCTGGCCGAGCGGCGCATCACCCTGGAGCTTTCCCCCGAGGCCAAGCGCTTCTTGGCCGAGCGCGGCTAC
GACCCGGTATTCGGGGCACGTCCCTTGAAGCGGGTGATCCAACGCGAACTCGAGACCCCCTTGGCCAAGAAGATCCTGGC
CGGCGAGGTACAAGACGGGGCCTACTTGCGGGTGAACGCCGGGCCACAAGGCCTCAGCTTTGAGGTTCAGGCCCCGGTAC
AAGCCTAA

Protein sequence :
MNLEVWTEQARQALAQAQVLAREFSHQAIDVPHLAAVLLKDPQGLPARLVGRAGGNPSSIYQAAQSELGRLPKVSGSEGG
QYLSNRLNAVFDRAEAIAKELGDKFVAVDTLTLALAETGYAGLPSISALRRAIQEIRGGKKVDSANAEGTYQALEQYGLD
LTALAEQGKLDPVIGRDEEIRRTVQILLRRTKNNPVLIGDPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIISLQMGSLLA
GAKYRGEFEERMKAVIQEAIQSAGEVILFVDELHTVVGAGKAEGAVDAGNMLKPALARGELHMIGATTLDEYREIEKDAA
LERRFQPVFVEEPSVEDTISILRGIKEKYEVHHGVRISDPAIVAAAVLSHRYISDRKLPDKAIDLIDEAAARIRMALESS
PEQIDSLERKKLQLEIERQALKKETDLESKARLDDIEAEIASLNEEIGKLKTEWEAEREVLKSLREAQQRLDEVRTSIEQ
AERAYDLNKAAELRYGELPRLEARVKELSEQLRNAKFVRLEVTEEDIAQVVSRWTGIPVAKLLEGEREKLLRLEEEMHKR
VVGQDEAIVAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAAQLFDTEENMVRIDMSEYQEKHTVARLIGA
PPGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNVLLQILDDGRLTDGQGRTVDFRNTVIILTSNLGSPLILEGI
QAGLPYETIRNRVFEVLQKNFRPEFLNRLDEIVVFKPLTQEQIAQIVEIQLEGLRRRLAERRITLELSPEAKRFLAERGY
DPVFGARPLKRVIQRELETPLAKKILAGEVQDGAYLRVNAGPQGLSFEVQAPVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-102 45
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-100 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-100 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_0416 YP_003683864.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-110 45