Gene Information

Name : Mesil_3146 (Mesil_3146)
Accession : YP_003686481.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3196920 - 3197576 bp
Length : 657 bp
Strand : -
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: azc:AZC_1953 response regulator receiver; PFAM: response regulator receiver; transcriptional r

DNA sequence : 
ATGCGTATTTTGCTGGTGGAGGACGACCTCGAGGTAGGGTCTTTGGTCAAGGAAACCCTCGAGGCCGAGCCCTACGCGGT
GGACTGGGCCCAGGATGGCGAGGAGGCCCTGGGGCTTTGGCAGAGCTTTCCCTATGACCTGGTGGTGCTGGACGTGGGCC
TGCCCCGGCGGGATGGCTTCAGCCTGCTGACCCACCTGCGCGGACAGGGCGGTGCGGCACCGGTGCTGATGCTGACCGCC
CGCGACGGCCTGGACGATCGGGTACGGGGCCTGGAGGCGGGGGCCGATGATTACCTGATCAAACCCTTTCACCTGCGCGA
ACTCCGGGCCCGGGTACGGGCTTTGCTGCGCCGCTCCCGGGGGGTATCCAGCAACCGGGTCGAGGTCGGACGGCTCTCCC
TCGATCTCCGGGCCAAGCAGGCCTGGTGGGAAGGGGAACCGCTCGAGCTTTCTGCCAAAGAGTGGCTGATTCTGGAGTTT
CTCTCCCTGCACCCTGACACCTTTTACCCCCGGGAATCCCTCCTCGAACACGTCTGGCCTGGCGAGGCCAGCATCGACCC
CCGTAGCCTCGACCCGTACATCTCTCGCCTGCGCCAAAAGCTGGCCCCGGAGGCCATCGAGACCCGGCGCGGACTGGGCT
ACCGTCTAGTGGGATGA

Protein sequence : 
MRILLVEDDLEVGSLVKETLEAEPYAVDWAQDGEEALGLWQSFPYDLVVLDVGLPRRDGFSLLTHLRGQGGAAPVLMLTA
RDGLDDRVRGLEAGADDYLIKPFHLRELRARVRALLRRSRGVSSNRVEVGRLSLDLRAKQAWWEGEPLELSAKEWLILEF
LSLHPDTFYPRESLLEHVWPGEASIDPRSLDPYISRLRQKLAPEAIETRRGLGYRLVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 4e-26 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator BAC0487 Protein 2e-26 45
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator CP000647.1.gene4257. Protein 2e-16 42
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator CP001138.1.gene4273. Protein 2e-16 42
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator BAC0533 Protein 2e-16 42
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator CP004022.1.gene3215. Protein 1e-22 42
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator NC_002516.2.879194.p Protein 2e-26 42
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator CP000034.1.gene3834. Protein 3e-16 41
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator NC_002695.1.915041.p Protein 3e-16 41
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator BAC0197 Protein 1e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_3146 YP_003686481.1 winged helix family two component transcriptional regulator VFG0473 Protein 2e-27 43