Gene Information

Name : Mesil_3095 (Mesil_3095)
Accession : YP_003686435.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 3141168 - 3142508 bp
Length : 1341 bp
Strand : +
Note : COGs: COG0305 Replicative DNA helicase; InterProIPR007693:IPR016136:IPR007694:IPR003593:IPR 007692; KEGG: ttj:TTHA1470 replicative DNA helicase DnaB; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase; SPTR: C1XUS2 Primary replicative DN

DNA sequence :
ATGGAAGGTCGCATCCCTCCCCACAACCTAGAAGCCGAAGCCAGCGTGCTGGGTTCCGTGTTGCTCGATAGCGAGGTGCT
GGATCGGCTCGAGGGCATCCTCACCGCCGAGTCTTTCTACAAGGAAGGCCACCGCAAGATCTGGACCTGCATGGAGCAGC
TCCGCATGCGGGGCGAGCCGGTAGACCTGGTGACCCTCTCCAACGAACTCGCCACCCGGGGAGAACTCGATGTAGCCGGA
GGCCTCTCGTATCTGGTAGGGCTCTCGGAAAATACACCCACCGCCGCCTATGCGGAGTACTACGCGCGAATCGTAGCGGA
GAAGTGGACCTTGCGCCGGTTGATCGAAGCCGCAGGGGAAGCCATGAAGATGGCCTACGAGGAGTCAGGAAGCCTCGAGG
AGATCCTAGACGGGGCCGGGCGAAGGGTGCTCGAGGTAGCCCTAGCAGGCAGCAAAACCGAGTTCCAAAACATGCGCGAC
CTGGTGCACGAAACCTTCGAGCACATCCAGCAGCTTTACGAAAACCAGGGAGCTACCACCGGGCTACGCAGCGGGTTCCG
CGAACTCGACCTGATGATCGGAGGGTTCACCCCGGGGTCCTTGAACATCATCGCCGCTAGGCCCTCCATGGGAAAAACTG
CTTTTGCCCTGACCATCGCACAAAACGTGGCCCTGCGCGAGAACATAGGGGTGGCGATCTTTTCCCTGGAGATGCCCGCC
GTGCAGCTCGTCACCCGCATGATGTGCTCGGAGGCGCGCATCGATATGAACCGGCTGCGGCAGGGCCAGCTTACCGACCG
GGACTTCTCGCGGCTGGTAGACGTAGCTGGGCGCATCGCCGAGGCCCCCATCCTCATCGACGATAGCTCCGACATGACCC
TGATGGAACTAAGAAGCCGGGCGCGACGCTTGATGAGCCAGCAAAAGCTAGGGCTAATCGTGATCGACTACTTGCAGCTC
ATGTCTGGCCCGACCTCGAGCCGCAACGGAGGTGGAGAGAACCGCCAACAGGAGATCGCGGCGATCTCGCGTGGTCTCAA
AGGACTGGCCCGCGAACTGAGCGTGCCGGTAATTGCCCTCTCCCAGCTCTCGCGGGCGGTGGAGGCAAGGCCCAACAAAC
GCCCCATGCTCTCTGACCTGAGGGAATCGGGATCCATCGAGCAAGACGCCGACCTGGTGATGTTTATCTACCGCGACGAC
TACTACAACCCCCACTCCGAGAAAGCCGGAATTGCCGAGATCATCGTAGGGAAGCAGCGCAATGGCCCCACCGGCACCGC
CGAGCTACAGTTCCATGCGCAGCATGTGCGCTTCAACGACCTGGCCAGAGATGAGGTGTGA

Protein sequence :
MEGRIPPHNLEAEASVLGSVLLDSEVLDRLEGILTAESFYKEGHRKIWTCMEQLRMRGEPVDLVTLSNELATRGELDVAG
GLSYLVGLSENTPTAAYAEYYARIVAEKWTLRRLIEAAGEAMKMAYEESGSLEEILDGAGRRVLEVALAGSKTEFQNMRD
LVHETFEHIQQLYENQGATTGLRSGFRELDLMIGGFTPGSLNIIAARPSMGKTAFALTIAQNVALRENIGVAIFSLEMPA
VQLVTRMMCSEARIDMNRLRQGQLTDRDFSRLVDVAGRIAEAPILIDDSSDMTLMELRSRARRLMSQQKLGLIVIDYLQL
MSGPTSSRNGGGENRQQEIAAISRGLKGLARELSVPVIALSQLSRAVEARPNKRPMLSDLRESGSIEQDADLVMFIYRDD
YYNPHSEKAGIAEIIVGKQRNGPTGTAELQFHAQHVRFNDLARDEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 3e-68 42
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 2e-64 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 2e-64 42
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 5e-77 41