Gene Information

Name : Mesil_2802 (Mesil_2802)
Accession : YP_003686154.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Resistance
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2854361 - 2855020 bp
Length : 660 bp
Strand : +
Note : COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867:IPR001789:IPR011991:IPR011006; KEGG: ttj:TTHA1722 putative response regulator; PFAM: response regulator receiver; transcr

DNA sequence :
ATGCCAGCCAAAGTACTGGTCGTAGAAGACGATCCGGGCATTCGTATGTTGGTCGCTACCACCCTGCAATCGGCGGGGCT
CGCCGTGCTGGAAGCCCGCGACGGCGTCGAGGCCATGGACTTCATACCGGAAGCGGACCTGGTGGTGCTCGACGTGGGCC
TGCCACGGCAATCTGGCTGGGAAGTCCTGGAGGCCATCCGCCAGAACTTCGGCCAGTTGCCGGTGCTGATGCTCACCGGC
CACTCCGACGAGACCAACCGGGTGCGGGGCCTCGAGAGCGGAGCCGATGACTACCTCACCAAACCCTTTAGCGTGCGTGA
GCTAGCTGCTCGGGTGAAGGCCCTGCTGCGTCGTTCGGGCCGACTAGGGCTCATCGTGATGGGCTCGCTCAAGCTCTCCC
CCGGCAGCCGCGAAGCCTGGCTCGACAACGACACGCTGCACCTCACGCCTTTGGAGTTCGATCTGCTGATGACCTTGGCC
CAGGCCCCCGGGCGCATCTTCAGCCGCGAGGAACTGCTGGTGCGGCACTGGGGCGCCGAGTACGAGGGCACCGAGCGGGT
CGTGGACATCTACATTGGCCGACTGCGCAAAAAGCTCCTCACCGAGTCGGATCGGCTCGAGACGGTGTGGGGTCAGGGCT
ACCGGCTCAGGAGCGATTAG

Protein sequence :
MPAKVLVVEDDPGIRMLVATTLQSAGLAVLEARDGVEAMDFIPEADLVVLDVGLPRQSGWEVLEAIRQNFGQLPVLMLTG
HSDETNRVRGLESGADDYLTKPFSVRELAARVKALLRRSGRLGLIVMGSLKLSPGSREAWLDNDTLHLTPLEFDLLMTLA
QAPGRIFSREELLVRHWGAEYEGTERVVDIYIGRLRKKLLTESDRLETVWGQGYRLRSD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 8e-33 44
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 5e-32 44
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 7e-30 41
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 2e-24 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 4e-38 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator CP001918.1.gene5135. Protein 1e-21 43
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator AF310956.2.orf0.gene Protein 3e-30 41
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator NC_002695.1.915041.p Protein 3e-24 41
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator BAC0533 Protein 2e-24 41
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator CP000034.1.gene3834. Protein 3e-24 41
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator CP000647.1.gene4257. Protein 2e-24 41
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator CP001138.1.gene4273. Protein 8e-25 41
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator CP004022.1.gene3215. Protein 5e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator VFG1563 Protein 4e-33 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator VFG1702 Protein 2e-32 44
Mesil_2802 YP_003686154.1 winged helix family two component transcriptional regulator VFG1389 Protein 2e-28 41