Gene Information

Name : Mesil_2631 (Mesil_2631)
Accession : YP_003685988.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Resistance
Product : rhodanese domain-containing protein
Function : -
COG functional category : R : General function prediction only
COG ID : COG0491
EC number : -
Position : 2675634 - 2677076 bp
Length : 1443 bp
Strand : -
Note : COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763:IPR001307:IPR001279; KEGG: ttj:TTHA0837 metallo-beta-lactamase family protein; PFAM: Rhodanese domain protein; SMART: beta-lactamase domain protein; Rhodanese domain protein; SP

DNA sequence :
ATGTTGTTCAAACAGATCTACGAGGAAGGATTGGCCCAGGCGAGCTATCTGATCGGTTGTCAGGCTTCGGGCGAAGCCAT
GGTGGTAGACCCTAAGCGAGACATCGACACCTACCTCGAGGAAGCTCGGAAAAACGGCCTGAAGATCGTGGCCGTCAGCG
AGACCCACATTCACGCGGATTACCTTTCGGGGGCGCGGGAGCTGGCCCAGGCCACCGGGGCTACCCTCTACCTCTCGGAT
GAGGGAGACGAATACTGGAAGTACAGTGGGCTGGAGGGCTTCAAGCACCAACTGCTCCGAGACGGTGACGAGATCCGGCT
AGGCAACGTGCGGGTCAAGGCGGTACACACCCCCGGCCACACTCCCGAGCATCTGTCTTTCTTGGTCACCGACGGGGCGG
CGGCGGGTGAACCAGGCTTCCTCCTCACCGGGGACTTTGTATTTGTGGGGGATATTGGTCGTCCGGACTTGCTCGAGGAG
GCTGCCGGAATTGTTGGGACCGCCGAACCGGGCGCGCGGCGAATGTTTAAAAGCCTGAAGGAGAAGTTTCTGACCCTGCC
CGACTACGTGCAGGTCTGGCCCGGCCACGGGGCAGGCTCGGCCTGCGGCAAGGCCTTGGGTGCGGTGCCCAGCAGCACCG
TGGGATATGAGCGGCGCTTCGCCTGGTGGGCTGATTACCTGGCTAAGGACGATGAAGAAGGTTTTGTGAAGGCCCTCCTT
TCTGGCCAACCAGAGGCCCCCAGCTACTTTGCCGTGATGAAACGCCTCAATCGCGACGGGATGACGATTCTGGGCGACCT
ACCCCAGCCCCATCGGCTCACTCCCGAGCAGTTCCGCCAGGCCTTGCAGGGAGGGGCGGTGCTAGTGGATACCCGCGACA
AGTTTGCCTTTGCCGGGGGACACCTTCCCGGCTCTCTCAACATCCCGGCGGGCAAGAACTTCTCTACCTGGGCGGGTTGG
TTGCTGCCCTATGACCGCCCGCTGGTGCTCCTGGCCGGGAGCGAGGCCGTGCAGGGCTTGGTGCGCCAGTTGGTGCGGAT
TGGCCTGGATAGGATAGTAGGATACATCCCCAGCTTGGAGGGCTATGCCGAGGGCGAACTCGAGGCCGTTCCCCAAGCGA
GCGCCGCCGAGGTCAAGGCGAAGTGGGAGCGGGGTGAGGTTTTGATCCTCGATGTGCGCGGGGCGGATGAGTACAAGGCT
GCGCATATCCCGGGTGCGCTCAACATCCACGCGGGGCGGGTGATGCAGAACCTACAGCGTATCCCCAAGGATCGGCCGAT
AGTGCTGCACTGCCTGGGTGGGGATCGCTCCTCCACTGCCATCAGTGCCCTGCTGGCGGCGGGCTACTCCAACGTCAGCA
ACCTGACCGGTGGGATCAAAGCTTGGCAGGAGCACGGCTTTCCTCTGGAAAAAGGTGAAGCGCCTCAACCGGTGGGGGCT
TAG

Protein sequence :
MLFKQIYEEGLAQASYLIGCQASGEAMVVDPKRDIDTYLEEARKNGLKIVAVSETHIHADYLSGARELAQATGATLYLSD
EGDEYWKYSGLEGFKHQLLRDGDEIRLGNVRVKAVHTPGHTPEHLSFLVTDGAAAGEPGFLLTGDFVFVGDIGRPDLLEE
AAGIVGTAEPGARRMFKSLKEKFLTLPDYVQVWPGHGAGSACGKALGAVPSSTVGYERRFAWWADYLAKDDEEGFVKALL
SGQPEAPSYFAVMKRLNRDGMTILGDLPQPHRLTPEQFRQALQGGAVLVDTRDKFAFAGGHLPGSLNIPAGKNFSTWAGW
LLPYDRPLVLLAGSEAVQGLVRQLVRIGLDRIVGYIPSLEGYAEGELEAVPQASAAEVKAKWERGEVLILDVRGADEYKA
AHIPGALNIHAGRVMQNLQRIPKDRPIVLHCLGGDRSSTAISALLAAGYSNVSNLTGGIKAWQEHGFPLEKGEAPQPVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 3e-82 42
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 2e-82 42
unnamed BAB83478.1 - Not tested SCC 12263 Protein 2e-82 42