Gene Information

Name : Mesil_2311 (Mesil_2311)
Accession : YP_003685678.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Unknown
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2340937 - 2342457 bp
Length : 1521 bp
Strand : +
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR016160:IPR016161:IPR015590:IPR011985:IPR 016162; KEGG: ttj:TTHA0959 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831; PFAM: Aldehyde Dehydrogenase; PRIAM: Betaine-a

DNA sequence :
TTGAAAATCGCTGAAAAAACCGCCCGTATTAGCCCTGAGTTTATCGCTCAGGTGCGGCAGAAAATCTCCTCGAGCCCCGT
TACCCACTTCATCGGGGGGGAGTTTGTGGCGGGGGCTCGAGGCCAGATCTTCGAGAGCTTAGATCCCTCGAACAACCAGG
TACTTGCCCACGTTTACCGGGGCCACGCCGAGGACGTCGACCAGGCTGCTCGGGCTGCGCGGGCCGCCTTCGACAAGTGG
AGGCTCTCCGCCAAAGCGCGCAAAAAGTACCTGCTCAAGATTGCGGAGTTGCTGGAAAAGCACGCCGACGAGTTAGCCGT
GATCGAGTGCCTGGACGCAGGCCAGGTGCTGCGTATCGTGCGGTCTCAGGTAGCCAGGGCGGCAGAAAACTTCAGCTTTT
ACGCGGAGTGGGCCGAGCGGGCCATGGATGGGCGCACCTACCCGGTGGATGCCGAGTGGATCAACTACACCGTGCGGGTG
CCGGTAGGGGTCTGCGGGATCATCACCCCCTGGAACGCCCCGCTGATGCTTTCCACCTGGCGCATCGCCCCCGCGTTGGC
TTTCGGCAACACGGTGGTTCTAAAGCCCGCCGAGTGGTCGCCCCTCACCGCCTGGAAACTGGCCGAGGTGATCCAGGAAG
CCGATCTGCCGCCCGGCGTGTTCAACGTGGTACAGGGCTTTGGCGAGGAGGCGGGCGACGCCTTAGTGCGCCACCCCGAG
GTGCCGCTGATCTCATTCACCGGCGAGACCACCACCGGCTCGATCATCACCCAGAACTCCGCTTTATATCTCAAGCGGCT
CTCCCTCGAGCTAGGGGGCAAATCCCCCGCGATTATTTTCCAGGATGCCGACCTCGAGCGGGCCACCGACGCCACTATCT
TCCAAATCTATAGCTTCAACGGCGAGCGCTGCACAGCGAATTCCCGTGCCTTGGTGCACGAGAGCATCCTGGAGGAGTTC
GTAAACCGGGTAGCCGAGCGGGCCGCGCGGGTGAAAGTCGGCCACCCCCTCGACCCAGAGACCGAGGTGGGGCCCTTGAT
CCACCCGGAGCACCTGGAGCGCGTCCTAGGCTACGTGCAGATCGGGCAGGAGGAAGGGGCCAAGCGGGTGGTGGGTGGCG
AGCGCGTGGGCGACAGAGGCAACTACATCTCCCCTGGCCTCTTCGTGGGCGAAAACCACATGCGCATCGCCCAGGAGGAG
ATTTTCGGCCCGATTCTGACGGTGATTCCCTTCAAAGACGAAGCCGAAGCCCTACGCAAAGCCAACGACGTGAAGTACGG
TCTGGCCGCCTACGTCTGGACTAAGGACGTGACCCGGGCGCACCGCGTGGCGCTGCACCTGGAAGCGGGCATGACCTGGA
TCAACTCGCACAACGTCCGACACCTGCCTACCCCCTTCGGAGGGATGAAGTTCTCGGGGACCCACCGCGAGGGAGGAGAA
TATAGCCTGGAGTTTTACACCGAGCTCAAGAACATCGCCCTGCCCTTGGGCGAGCACCCCATCCCCAAGTTCGGGAAATA
G

Protein sequence :
MKIAEKTARISPEFIAQVRQKISSSPVTHFIGGEFVAGARGQIFESLDPSNNQVLAHVYRGHAEDVDQAARAARAAFDKW
RLSAKARKKYLLKIAELLEKHADELAVIECLDAGQVLRIVRSQVARAAENFSFYAEWAERAMDGRTYPVDAEWINYTVRV
PVGVCGIITPWNAPLMLSTWRIAPALAFGNTVVLKPAEWSPLTAWKLAEVIQEADLPPGVFNVVQGFGEEAGDALVRHPE
VPLISFTGETTTGSIITQNSALYLKRLSLELGGKSPAIIFQDADLERATDATIFQIYSFNGERCTANSRALVHESILEEF
VNRVAERAARVKVGHPLDPETEVGPLIHPEHLERVLGYVQIGQEEGAKRVVGGERVGDRGNYISPGLFVGENHMRIAQEE
IFGPILTVIPFKDEAEALRKANDVKYGLAAYVWTKDVTRAHRVALHLEAGMTWINSHNVRHLPTPFGGMKFSGTHREGGE
YSLEFYTELKNIALPLGEHPIPKFGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-106 51
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-73 42