Gene Information

Name : Mesil_2184 (Mesil_2184)
Accession : YP_003685562.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2200194 - 2201717 bp
Length : 1524 bp
Strand : -
Note : COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR001317:IPR011063:IPR017926:IPR001674:IPR 004739:IPR011702:IPR006220:IPR000991:IPR014729; KEGG: ttj:TTHA1552 GMP synthase; PFAM: glutamine amidotransferase class-I; GMP synthase domain protein

DNA sequence :
ATGAGCGTCGTCATCCTCGATTACGGCTCGCAGTACACCCGGCTCATCGCCCGGCGCGTCCGGGAGCTGAGGGCTTTTTC
GGTTATCTTACCGGGAACAGCTCCGCTGGAGCGGATTCTGGCGGAAAAGCCCCAGGCGATTATCTTATCGGGTGGTCCCA
ACTCGGTCTTCGACCCGGCAGCACCACGAGCGGCGGAGGGATTGCTCGAGCAGAACCTCCCCATCCTCGGCATTTGCTAC
GGGATGCAACTGTTGGCCCAGCACCTCGGCGGGCGTGTCGAGCGGGCTGGGCGGCGCGAGTATGGTAAGGCCTTCCTCTC
CCGCCACGAAGGGCCACTTTTTGCCGGGCTGGAGGGAGAAATCCAGGTTTGGATGAGCCATTCCGATGCCGTCACCCAGC
TCCCCCCAGGGTGGCAGGTGATCGCCGAAACCGAGGAGAACCCGGTAGCAGCCATCGCCGCGCCAGACGGCAGAACCTTC
GGGGTGCAGTTTCATCCCGAGGTGGTGCATAGCCCCAAAGGCATGACTATACTGGAAAACTTCCTGGAACTGGCTGGAGT
GGCCCGGGACTGGACCCCAGAGCACACCCTCGAGACCCTGATCGAGGAGATCCGGGCTAAGGTGGGCCGGGACCGGGTAA
TGCTGGCGGTCTCCGGTGGAGTGGACTCGTCGACGCTGGCCTTGCTGCTCTCGAGGGCGGTAGGTGACAAGCTCACCGCG
ATCTTCGTGGACCATGGCTTGTTGCGCCAGGGGGAGCGCCATGAGGTCGAAGCCGCCCTGCGCCCTTTGGGTGACGGATT
CCGGGTAGTGGATGCCGCGGAACAGTTCCTCACGGCCCTTAAAGGGGTAAGCGACCCCGAGGAAAAGCGCCGGGTGGTAG
GGCGCGAGTTCATAAGGGTGTTTGAGGCCGAAGCCCGCAAACTCTCACAGGAAGGCTACCGTTGGCTGGCCCAGGGTACC
CTTTATCCCGACGTGATCGAATCGGCGGGCGGGGAGGGGGCGGCCAACATCAAAAGCCACCATAACGTGGGCGGGCTGCC
CCCTGATTTGAAGTTTGAGCTGCTCGAGCCTTTCCGCTACCTTTTCAAAGACGAGGTGCGCGAACTGGCCCTGCTCTTGG
GGCTCCCCGAGCATATCCGCATGCGCCACCCCTTCCCCGGGCCGGGCCTGGCGATTCGCATCCTGGGGGAAGTTACGCGA
GAGAAACTCGATATCCTGCGCCGGGCCGATGATATTTTTATCAGCGCTCTGCGCGACTGGAATCTCTACGACAGCGTTGC
TCAAGCGCTGGCTGTACTTACTCCGGTACAGAGCGTGGGGGTTGTTGGGGACGAGCGCAGCTACGGCTACGTGCTGGGCT
TGCGGGCGGTGAGCACGGTGGACTTCATGACCGCCGACTGGGCCCGCTTGCCCTGGGAGTTCCTCGACGAGGTGGCCCGC
AAGATCACCCGCCAGGTGCCGGAAGTCGGGCGGGTGGTCTACGACATCACCAGCAAGCCCCCTGCGACCATTGAGTGGGA
ATGA

Protein sequence :
MSVVILDYGSQYTRLIARRVRELRAFSVILPGTAPLERILAEKPQAIILSGGPNSVFDPAAPRAAEGLLEQNLPILGICY
GMQLLAQHLGGRVERAGRREYGKAFLSRHEGPLFAGLEGEIQVWMSHSDAVTQLPPGWQVIAETEENPVAAIAAPDGRTF
GVQFHPEVVHSPKGMTILENFLELAGVARDWTPEHTLETLIEEIRAKVGRDRVMLAVSGGVDSSTLALLLSRAVGDKLTA
IFVDHGLLRQGERHEVEAALRPLGDGFRVVDAAEQFLTALKGVSDPEEKRRVVGREFIRVFEAEARKLSQEGYRWLAQGT
LYPDVIESAGGEGAANIKSHHNVGGLPPDLKFELLEPFRYLFKDEVRELALLLGLPEHIRMRHPFPGPGLAIRILGEVTR
EKLDILRRADDIFISALRDWNLYDSVAQALAVLTPVQSVGVVGDERSYGYVLGLRAVSTVDFMTADWARLPWEFLDEVAR
KITRQVPEVGRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-121 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-121 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-121 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-121 50