Gene Information

Name : Mesil_1520 (Mesil_1520)
Accession : YP_003684918.1
Strain : Meiothermus silvanus DSM 9946
Genome accession: NC_014212
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 1518359 - 1520905 bp
Length : 2547 bp
Strand : +
Note : COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR016151:IPR000432:IPR005748:IPR007860:IPR 007696:IPR007695:IPR007861; KEGG: ttj:TTHA1324 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS domain protein; MutS II domain

DNA sequence :
ATGATCCTCAAGGGCCAAGGTAGCGGCCCCTTGCCGCCGCTGCTGCAGCAATACGTTGAGTTGCGTGACGCTTACCCGGA
TTACCTTTTGCTGTTTCAAGTGGGCGATTTTTACGAGGCTTTTGGCGAGGACGCCGAGCGGCTTTCCCGCGCTTTGGGGA
TCACCCTTACCCACAAAACCAGCAAAGACTTTACTACCCCTATGGCGGGAATCCCGATTCGATCCGCCGATAGCCACCTC
GAGCGCCTCCTCAAGATGGGCTTCCGGGTCGGGCTGGCCGAGCAAACCGAGCCAGTAGAAGCTGCCGAGGGGTTGGTAAG
GCGAGAGGTCACCCAGCTCCTCACCCCCGGCACCCTGACCCGGGAAAACCTCCTTCGCCCGGATGCCAACTACCTGGCGG
CTATTGCTACCGGGGAGGGGTACGGGGTGGTGTTTTTGGAAGTATCGACGGGGGAGTTTCGGGGAGTAGTGCTTTACAGC
AAAAGCGCTCTGTACGATGAGCTTTTTCGCAACCGCCCCGCCGAGGTGCTGCTAGCTCCCGAGCTGTATGCTAACGAGGC
CTTTCGCGAAGAGTTTCAGCGGCGCTTTCCGCTGATGGTCTCTTCGGGCAGCTTTGACCCGCAGGGGGCGCGAAGCGCGC
TGGTGCAGCAGTTCGGGATGCTTCCCTCTGGGCTCGACCATCCCGCTTTGGAACGCGCAGCCGGGGCGGTGCTGGCTTAC
GCCCGAACCACCCAAGCCGGCGCGCTGCCCCAGGTACGCGGGTTCGCGCGTTACGATCCCAGCGCTTACATGCAGCTTTC
TGAGACCACCCTGCGCACCCTCGAGGTCTACGACCCCAGCCCCGTGGGTTCGTACCTCCCCGTGGGGGAGGAGCGCACCC
TGATGGGAGTGCTGGGGTTGACCCGTACCGCTCCGGGGCGGCGGCTCCTTAAGGCTTGGCTGCGTCAACCGCTCCTGGAC
GAAGGTCCTATCCAGGCTCGGCTAGACGCGGTGGAGGCCTTGGTGCGCGATAGCGTGTTGCGCGAGGCGGTGCGGCGGCT
TTTGTACCGCATCCATGACCTCGAGCGCCTCGCTGCTCGGTTGGCTGCAGGCCGTTCCAATGCCCGTGATTTGGCTGCTT
TGGCCCGCAGCCTGGGGCTTCTGCCCGAACTCCAAGGCCAATTGTTGGCCTGCGAGCCCTTGCGGGTATTGGCAGAGCGG
TTGCCACTGCTCGCTGAGGTAGTTGAGCGCATTAGCGCCGCGTTGGTCGAGGAGCCTCCGCTCAAGATCACCGAGGGCGG
GTTGATCAAAGATGGCTTCGACGCTACCCTAGACGCTCACCGTGAGCGGGCTGAGGCGGGGCGTAGCTGGATCGCCGGGC
TCGAGGCCGCTGAGCGTTCACGCACCGGCATCCCCAGCCTCAAGGTGGGGTACAACCAGGTGATGGGCTACTACCTCGAG
GTCACCCGCCCCTACTATGCACAAGTACCCTCGGACTGGCGTATTGTGGCTACCCTCAAAGACCGCCAGCGCTATACCCG
TCCGGATCTGCGCGAAAAAGAACGGGAGATCCTGCTGGCCGAGGAAGCCGGGCGCAAACGCGAGTACGAGGTTTTTCAGG
AACTCCGGGAAGAGTTAAGCGGCCAGGCCGAGCGGGTGCGCGAGGCGGCCTTGGTGCTGGCGGAGCTGGATGTGTATGCG
ACGCTGGCCGAGGTGGCTGCCCGGCATGGCTATACCCGACCCCGTTTCAGCCCCGATCGTCTGTTCATTCGGGCAGGGCG
GCACCCGGTGGTGGAGAGACACCTCGAGGGTAGGTTCATCGCTAACGACCTCGAGATGGGCCCTGAGGCCCGGCTGCTGA
TCCTTACCGGCCCCAACATGAGCGGTAAGTCCACCTACTTGCGCCAGACTGCGCTCATCGCTCTCCTGGGTCAGATCGGT
TCTTTCGTGCCCGCCGAGGAAGCCGTACTGCCCATTTTTGACCGCATCTATACCCGTATTGGGGCTGCCGACGATATTGC
GGGGGGGCGCAGCACCTTTATGGTGGAGATGGAAGAACTCGCTCAGATCCTCCAGGGGGCCACCGCCAGAAGCCTGGTCT
TGCTCGATGAGATCGGGCGGGGAACCAGCACCTATGACGGTCTCAGCCTGGCTTGGGCGGCCAGCGAGTACCTGCATGAC
CGCATAAAGGCCCTAACCCTCTTTGCCACCCACTACTTCGAACTCACTGCCCTCCCCGAAACCCTCCCCGCAGCCCGCAA
CTATCATGTAGCTGCCCGGGAGGAGGTTGGGGGGTTGGTTTTTTATCACCAGGTGTTGCCGGGTCCAGCTTCTAAGAGTT
ATGGCCTCGAGGTGGCCCGCCTGGCCGGGTTGCCGCCCGAGGTTTTGGGGCGGGCCGGACAACTGTTGGCGGGGCTCGAG
GCCCGCCGGGACGACTGGAGCCAAGCCCTCGCGGAGGAACTGCTGGCCCTCGACCTCACCCGCCTCACCCCCCTGGAGGC
CTTGCTCAAGCTCCAACAACTGCGGGAGAGACTCTACCCGGTGATGGTTTCAGAAGCCGCGGACTAG

Protein sequence :
MILKGQGSGPLPPLLQQYVELRDAYPDYLLLFQVGDFYEAFGEDAERLSRALGITLTHKTSKDFTTPMAGIPIRSADSHL
ERLLKMGFRVGLAEQTEPVEAAEGLVRREVTQLLTPGTLTRENLLRPDANYLAAIATGEGYGVVFLEVSTGEFRGVVLYS
KSALYDELFRNRPAEVLLAPELYANEAFREEFQRRFPLMVSSGSFDPQGARSALVQQFGMLPSGLDHPALERAAGAVLAY
ARTTQAGALPQVRGFARYDPSAYMQLSETTLRTLEVYDPSPVGSYLPVGEERTLMGVLGLTRTAPGRRLLKAWLRQPLLD
EGPIQARLDAVEALVRDSVLREAVRRLLYRIHDLERLAARLAAGRSNARDLAALARSLGLLPELQGQLLACEPLRVLAER
LPLLAEVVERISAALVEEPPLKITEGGLIKDGFDATLDAHRERAEAGRSWIAGLEAAERSRTGIPSLKVGYNQVMGYYLE
VTRPYYAQVPSDWRIVATLKDRQRYTRPDLREKEREILLAEEAGRKREYEVFQELREELSGQAERVREAALVLAELDVYA
TLAEVAARHGYTRPRFSPDRLFIRAGRHPVVERHLEGRFIANDLEMGPEARLLILTGPNMSGKSTYLRQTALIALLGQIG
SFVPAEEAVLPIFDRIYTRIGAADDIAGGRSTFMVEMEELAQILQGATARSLVLLDEIGRGTSTYDGLSLAWAASEYLHD
RIKALTLFATHYFELTALPETLPAARNYHVAAREEVGGLVFYHQVLPGPASKSYGLEVARLAGLPPEVLGRAGQLLAGLE
ARRDDWSQALAEELLALDLTRLTPLEALLKLQQLRERLYPVMVSEAAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 4e-112 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mesil_1520 YP_003684918.1 DNA mismatch repair protein MutS VFG0562 Protein 7e-119 42