Gene Information

Name : Ndas_0085 (Ndas_0085)
Accession : YP_003678043.1
Strain :
Genome accession: NC_014210
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 109027 - 110172 bp
Length : 1146 bp
Strand : +
Note : COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277:IPR015424:IPR015422:IPR015421; KEGG: tfu:Tfu_0440 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: cystathionine ga

DNA sequence :
ATGAAGTTCGACGGGTTTGAAACGCTGGCCATCCACGCGGGGCAGGAGCCGGACGCCGGAACCGGGTCCGTGGTGGTGCC
GATCTACCAGACGAGCACCTACGCCCAGGACGGCGTGGGCGGTCTGCGCCAGGGCTACGAGTACTCGCGCACCGGCAACC
CCACGCGCGCGGCCCTGGAGGAGTGCCTGGCCGCCCTGGAGTCCGGGGTGCGCGGCCTGGCCTTCGCCTCCGGCATGGCC
GCCGAGGACACCCTGCTGCGCACGGTGCTCTCGCCCGGCGACCACCTGATCATCCCCGGCGACGCCTACGGCGGCACCTT
CCGCCTGGTCTCCAAGGTGGTCGAGCGCTGGGGTGTGCAGTGGGACGCGGTCGACCAGTCCGACCCCGAGGCCGTGCGCG
CGGCCGTGCGGCCCAACACCAGGGTGGTGTGGACCGAGACGCCCACCAACCCCCTGCTCAACATCACCGACATCGAGGCC
GTCGCGCAGATCGCGCACGACGCCGGCGCCCTGCACGTGGTCGACAACACCTTCGCCTCGTCCTACCTCCAGCAGCCGCT
GACCCTGGGCGCGGACGTGGTCGTGCACTCCACCACCAAGTACCTGGGCGGGCACTCCGACGTGGTCGGGGGAGCGCTGG
TGGTCTCCGACGCCGAGCTGGGCGAGCGGCTGGCCTTCCACCAGAACACCATGGGCGCGGTCCCGGGGCCGTTCGACTCC
TGGCTGACCCTGCGCGGGATCAAGACCCTGGGCGTGCGCATGGACCGGCACAGCGCCAACGCCGAGAAGGTGGTGGCGGC
CCTGGAGGGCCACCCCGCGGTGCGCCGGGTGTTCTACCCCGGGTTGGACGCCCACCCGGGGCACAAGACCGCCGAACGGC
AGATGAGGGCCTTCGGCGGCATGGTCTCCTTCGCCCTGCGCGACGGTGAGAAGGCGGCGCTCGCCCTGTGCGAGCGCACC
GAGGTCTTCACCCTCGGCGAGTCCCTGGGCGGGGTGGAGTCCCTGATCGAGCACCCGGGTCGGATGACGCACGCGTCCAC
CGCGGGCTCCCCGCTGGAGGTCCCGGCCGACCTGGTGCGGATCTCCGTGGGCATCGAGTCCGCCGACGACCTGGTGGCGG
ACCTGCTCCAGGCCCTGGAGGGCTAG

Protein sequence :
MKFDGFETLAIHAGQEPDAGTGSVVVPIYQTSTYAQDGVGGLRQGYEYSRTGNPTRAALEECLAALESGVRGLAFASGMA
AEDTLLRTVLSPGDHLIIPGDAYGGTFRLVSKVVERWGVQWDAVDQSDPEAVRAAVRPNTRVVWTETPTNPLLNITDIEA
VAQIAHDAGALHVVDNTFASSYLQQPLTLGADVVVHSTTKYLGGHSDVVGGALVVSDAELGERLAFHQNTMGAVPGPFDS
WLTLRGIKTLGVRMDRHSANAEKVVAALEGHPAVRRVFYPGLDAHPGHKTAERQMRAFGGMVSFALRDGEKAALALCERT
EVFTLGESLGGVESLIEHPGRMTHASTAGSPLEVPADLVRISVGIESADDLVADLLQALEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-78 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-79 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-58 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ndas_0085 YP_003678043.1 cystathionine gamma-synthase BAC0207 Protein 8e-59 43