Gene Information

Name : Ndas_3248 (Ndas_3248)
Accession : YP_003681160.1
Strain :
Genome accession: NC_014210
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 3882244 - 3883674 bp
Length : 1431 bp
Strand : -
Note : COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016162:IPR016161; KEGG: stp:Strop_0827 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; PRIAM: betaine-aldehyde dehydrogenase; SPTR: C1YSQ1 aldehyde dehydrogenase (Acceptor); P

DNA sequence : 
GTGATCTTCGAGTACGCGCCCGCACCGGAGTCCCGCTCCGTCGTCACCCTGCGCGAGAACTACGAGCTGTTCGTCGACGG
CGCCTTCTCCCCGGCCGAGGGCGGCGAGTACCTCACCACCCTCAACCCCGCCGACGAGACCGAGCTCGCCCGGGTCGCCG
TCGCCGGACCCGCCGACGTGGACCGGGCCGTCGCCGCCGCCCGCCGCGCCTTCGACACCGTCTGGGGGCCGATGCCCGGG
GCGGAGCGCGGCAAGTACCTGTTCCGCATCGCCCGCATCATCCAGGAGCGCTCGCGCGAGCTGGCCGTGCTGGAGTCGAT
GGACAACGGCAAGCCCATCAAGGAGACGCGCGACGTCGACCTGCCGCTGGTCGCCGCGCACTTCTTCTACCACGCGGGGT
GGGCCGACAAGCTCGCCCACGCCGGGCTGGGCCCCGACCCGCGCCCGCTGGGCGTGGCCGCCCAGGTCATCCCGTGGAAC
TTCCCGCTGCTCATGCTCGCGTGGAAGATCGCGCCGGCGCTGGCCACCGGCAACACCGTCGTGCTCAAGCCCGCCGAGAC
CACCCCGCTCACCGCGCTGGCCTTCGCCGAGATCTGCCAGGAGGCCGACCTGCCCCCGGGCGTGGTCAACATCCTCACCG
GCGCGGGCGAGACCGGCCGGGCCCTCGTGGAGCACCCGGGCGCCGACAAGGTGGCCTTCACCGGCTCCACCGGGGTGGGC
CGCCAGATCGCCCGCTCGGTCGCGGGCACCGGCAAGCGCCTCACCCTGGAGCTGGGCGGCAAGGGCGCCAACATCGTCTA
CGACGACGCGGCCCTGGACCAGGCGGTCGAGGGCGTCGTCTCGGGCATCTTCTTCAACCAGGGCCACGTGTGCTGCGCGG
GTTCGCGGCTGCTGGTCCAGGAGTCGATCGCCGAGGAACTGCTGCCCCGGCTCAAGGAGCGCATCGCCAAGCTGCGCCTG
GGCGACCCGCTGGACAAGAACACCGACATCGGCGCGATCAACTCCGCCGCGCAGCTGGAGCGCATCCGCGAACTCACCGA
CACCGGCGAGGAGGAGGGCGCCGAGCGCTGGTCGCCCGCCTGCGAGCTGCCCGCGAGCGGCTACTGGTTCGCGCCCACCG
TCCTGACCGGCGTCAGCCAGTCCCACCGCGTGGCCCGCGAGGAGATCTTCGGCCCCGTGCTCTCGGTGCTGACCTTCCGC
ACCCCCGAGGAGGCCGTGGCCAAGGCCAACAACACCCCCTACGGCCTCTCCGCCGGGGTGTGGACCGAGAAGGGCTCGCG
CATGCTCTGGACCGCCGAGCGCCTGCGCGCCGGGGTGATCTGGTCCAACACGTTCAACAAGTTCGACCCGACCAGCCCCT
TCGGCGGCTACAAGGAGTCGGGATACGGCCGCGAGGGCGGGCGGCACGGATTGGAGGCCTACCTTGGCTGA

Protein sequence : 
MIFEYAPAPESRSVVTLRENYELFVDGAFSPAEGGEYLTTLNPADETELARVAVAGPADVDRAVAAARRAFDTVWGPMPG
AERGKYLFRIARIIQERSRELAVLESMDNGKPIKETRDVDLPLVAAHFFYHAGWADKLAHAGLGPDPRPLGVAAQVIPWN
FPLLMLAWKIAPALATGNTVVLKPAETTPLTALAFAEICQEADLPPGVVNILTGAGETGRALVEHPGADKVAFTGSTGVG
RQIARSVAGTGKRLTLELGGKGANIVYDDAALDQAVEGVVSGIFFNQGHVCCAGSRLLVQESIAEELLPRLKERIAKLRL
GDPLDKNTDIGAINSAAQLERIRELTDTGEEEGAERWSPACELPASGYWFAPTVLTGVSQSHRVAREEIFGPVLSVLTFR
TPEEAVAKANNTPYGLSAGVWTEKGSRMLWTAERLRAGVIWSNTFNKFDPTSPFGGYKESGYGREGGRHGLEAYLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-67 43
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 5e-49 42
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 4e-49 42
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 1e-48 42
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 1e-48 42
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 6e-49 42
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 6e-49 42
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 6e-49 42
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 6e-49 42
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 4e-49 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-60 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-70 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-70 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-70 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ndas_3248 YP_003681160.1 betaine-aldehyde dehydrogenase VFG0082 Protein 6e-68 43