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Name : Tmath_2122 (Tmath_2122) Accession : YP_003677805.1 Strain : Thermoanaerobacter mathranii A3 Genome accession: NC_014209 Putative virulence/resistance : Resistance Product : D-alanine/D-alanine ligase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : - Position : 2143676 - 2144755 bp Length : 1080 bp Strand : - Note : KEGG: tpd:Teth39_0187 D-alanyl-alanine synthetase A; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein DNA sequence : ATGGTAAAGAAGAGAATTGCTGTTTTATTTGGAGGACAATCAGGAGAACATGAGGTCTCTTTAATGTCTGCAAAGTCTAT AATAAACAATCTCGATAAAGATAAATACGAGATTTACATGGTAGGTATTACAAAAAAAGGAGAATGGTATCTATATAGGG GTGACGTAGAGAAAATAGAAACCGGAGAATGGGAAAAAGAAGGAATTCCCGCAACTATGGGAGCTTCTACAAAGTATAGA GGAATAATAACTTTTGAAGAAGGAAAAAATGTTTTTTTTCCTATAGACGTGGTATTTCCTGTATTGCATGGCCCTAATGG AGAAGATGGGACTATACAAGGGCTTTTAGAATTATTGGATATACCTTACGTAGGTGCTAATGTGCTTTCTTCTGCTTTAT GCATGGATAAAGTTTTTACAAAAAGAATTTTTAAGGAAGCTGGATTGCCTACACCTGATTTTGTAGTAGTTTATAGAAAA GAAATTGGAGATTTAGAAACTATTAAAAAGAAAATTGAGCACTTAGGATATCCTTGTTTTGTAAAACCAGCTAATTTGGG ATCAAGTGTTGGTATTACCAAAGTCCACAACGAGGAAGAACTTCCTGGGGCCTTGAAATTAGCTGCAAAATATGATAGAA AATTGTTGATAGAAAAAGGAATAGAGGCCAGAGAGATTGAATGCTCTGTTTTGGGGAATGAAAATCCTGAGGCTTCTGTT GCGGGAGAAATTGTACCTTCAAATGAGTTTTATGATTACAATGCCAAATATTTTGATGGAGGAAAGTCACTTCTTTTAAT ACCTGCTCCACTACCTGATGAAAAAATGGAAGAGATAAGAAAGCTCGCTATAAAAGCCTACAGAGCCTTGGATTTAAGAG GCATGGCGAGAGTAGACTTTTTAATGGATAGAAATACAGGCACTGTTTACCTAAATGAAGTTAACACTATTCCGGGCTTT ACGAAAATAAGTATGTACCCTAAACTATGGGAAGCGAGTGGAAAGTCCTATTCGGCATTATTGGATGACCTTATAAATTT AGCAATAGAAAGTAATAATGAAAAATGTAGGGAATGGTGA Protein sequence : MVKKRIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVEKIETGEWEKEGIPATMGASTKYR GIITFEEGKNVFFPIDVVFPVLHGPNGEDGTIQGLLELLDIPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYRK EIGDLETIKKKIEHLGYPCFVKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIEKGIEAREIECSVLGNENPEASV AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEIRKLAIKAYRALDLRGMARVDFLMDRNTGTVYLNEVNTIPGF TKISMYPKLWEASGKSYSALLDDLINLAIESNNEKCREW |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 7e-56 | 41 |
| vanB | YP_008394259.1 | Vancomycin B-type resistance protein vanB, D-alanine--D-lactate ligase | Not tested | Not named | Protein | 7e-55 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AY489045.gene.p01 | Protein | 3e-56 | 43 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AF130997.1.orf4.gene | Protein | 4e-54 | 43 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AF277571.gene.p01 | Protein | 4e-56 | 42 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AF162694.gene.p01 | Protein | 4e-56 | 42 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AE016830.1.gene2250. | Protein | 3e-56 | 41 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | U00456.gene.p01 | Protein | 3e-56 | 41 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | U35369.1.gene6.p01 | Protein | 3e-56 | 41 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AF310956.2.orf5.gene | Protein | 2e-55 | 41 |
| Tmath_2122 | YP_003677805.1 | D-alanine/D-alanine ligase | AY145441.gene.p01 | Protein | 7e-56 | 41 |
