Gene Information

Name : Tmath_1864 (Tmath_1864)
Accession : YP_003677566.1
Strain : Thermoanaerobacter mathranii A3
Genome accession: NC_014209
Putative virulence/resistance : Unknown
Product : adenine-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 1887646 - 1889190 bp
Length : 1545 bp
Strand : -
Note : KEGG: mhu:Mhun_2789 N-6 DNA methylase; PFAM: N-6 DNA methylase

DNA sequence :
ATGGGTCAGAATAACGATGGAGTCTTAAATTTCGCTTCAACCCTCTGGGCAGCAGCTGACAGGTTAAGAAATAATATGGA
GCCGTCAGAATATAAGCATATTGTCCTTGGACTTATATTTTTGAAATATATTTCCGATGCATTTAAATTTCGCAAGGAGG
AGTTAGAGTATTTAATAAAAGACCCCAAAAGCGAAGAATATTACTGTGAAACTAATGAAGAGGCACAACTTATATTAGAG
GATAAAGACGAATATATGGCCGCGAATGTATTCTATGTTCCACCCGAGGCGAGATATGAGTATATTATGGCAAATGCTCG
TCGAAGCGATATTGGTAAGCTCATTGATAATGCTATGGATTTGATTGAAAAAGAAAATCCAAAGCAATTAAGAGGGGTAT
TACCGAAGGTATACACCAGAGCGCCTTTGGATCCGCACACTCTTGGTGAAATTGTTACCTTAATTGGCAGCATTAATTTT
GGTAAAAACGAGGAACTGGATGTTTTAGGGAGAGTTTATGAGTATTTTCTTTCCGAATTTGCCAGAAAAGAGGGTAAGAG
AGGTGGCGAGTTCTTTACGCCCTCAACTGTTGTCAAACTACTTGTTGAAATGATTCAGCCTCTTCATGGCAGGGTTTTTG
ACCCATGCTGCGGTTCTGGGGGCATGTTTGTCCAGAGCATACGCTTTGTAGAGGCTCATGCAGGCAAGAAGGGAGATATT
TCAATCTATGGGCAGGAATCCAATCCGACCACTTACAGGCTGTGTAAAATGAACCTTGCAATTCGGGGTATTGAGGCAGA
TATAAGGTTAGGGAATTCCTTCACAGATGACCAGTTTAAGGATCTAAGAGCAGATTATATATTGGCAAATCCGCCGTTCA
ATGACAGTGCCTGGGGAGCAGATAGGTTGGCGAATGATGTAAGATGGAAATACGGGCTGCCGCCTGATTCAAATGCAAAT
TATGCATGGATACAGCATTTTATTTACCACCTTGCACCGAAAGGCGTAGCTGGTTTTGTGCTCGCCAACGGTTCTATGAC
TACAAGCAATAATGCGGAGTATGAGATAAGAAAAAGGATCATAGAGGATAATCTTGTAGATTGCATGGTAGCACTACCAC
CACAGCTATTTTACACAACAGGAATTCCTGCATGTTTGTGGTTCATCCGCAAAGGCAGGGAAACGAAAGAAACTCTTTTC
ATTGATGCCAGGAAGATTGGTGTTATGGTGGACAGGACGCATAGAGAACTTACCGATGAGGAAATTCAAAAGATTGCACA
GACTTATCACAACTGGAGAAATAAGAATGGATATGAAGATGTAAAAGGCTTTTGCGCTTCGGTTCCTATGGAGGTTATCG
CACAAAACGATTATGTCCTTGCACCTGGAAGATATGTAGGTGTAGAGGATACGCGAGAAGATGATATACCTTTTGAAGAA
AAAATGGCAGAACTAACTGAGAAACTTTATCAGCAGATGAAGGAAGCAAAAAGGCTTGACGAGGTTATAAAGGCAAATCT
GGAGGAGTTGGGATATGGGGAGTGA

Protein sequence :
MGQNNDGVLNFASTLWAAADRLRNNMEPSEYKHIVLGLIFLKYISDAFKFRKEELEYLIKDPKSEEYYCETNEEAQLILE
DKDEYMAANVFYVPPEARYEYIMANARRSDIGKLIDNAMDLIEKENPKQLRGVLPKVYTRAPLDPHTLGEIVTLIGSINF
GKNEELDVLGRVYEYFLSEFARKEGKRGGEFFTPSTVVKLLVEMIQPLHGRVFDPCCGSGGMFVQSIRFVEAHAGKKGDI
SIYGQESNPTTYRLCKMNLAIRGIEADIRLGNSFTDDQFKDLRADYILANPPFNDSAWGADRLANDVRWKYGLPPDSNAN
YAWIQHFIYHLAPKGVAGFVLANGSMTTSNNAEYEIRKRIIEDNLVDCMVALPPQLFYTTGIPACLWFIRKGRETKETLF
IDARKIGVMVDRTHRELTDEEIQKIAQTYHNWRNKNGYEDVKGFCASVPMEVIAQNDYVLAPGRYVGVEDTREDDIPFEE
KMAELTEKLYQQMKEAKRLDEVIKANLEELGYGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 5e-142 57
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 3e-141 56
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 5e-141 55
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 6e-114 46