Gene Information

Name : Tmath_1619 (Tmath_1619)
Accession : YP_003677337.1
Strain : Thermoanaerobacter mathranii A3
Genome accession: NC_014209
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1606239 - 1607990 bp
Length : 1752 bp
Strand : -
Note : KEGG: tex:Teth514_1195 pyruvate kinase., pyruvate, water dikinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGCGCAGAACAAAAATAGTATGTACAATAGGACCTGCCAGCGAAGACTATAATATACTGAGAAAATTAATTGAGAAAGG
CATGAACGTTGCACGACTTAATTTTTCTCATGGAGATTTTGCAGAACATGGAGCGAGAATTGACAATATAAAAAAAATAA
GGCAAGAGTTGGGGTTGCCTGTTGCTATTTTATTAGACACAAAAGGTCCTGAGATAAGAACAGGAAAGTTTAAAAATGGC
GAAGTACAATTAAAAGAAGGACAAACTTTTGTCATTACGACAAGAGATGTATTAGGAGACGAAACTATATGCAGTGTATC
CTACAAAGGGTTGCCTCAAGATGTGGAAAGAGGCAGCCGCATATTAGTTGACGATGGGTTAATTTCTCTGAAGGTTACAG
ATGTTAAAGGAGAAGATATAGTTTGTATTGTAGAAAATTCTGGTCCTGTAAAAGATCATAAAGGAGTAAATGTTCCAGGG
GTAAAACTCAATCTTCCTGCATTAACTCAAAAAGACATAGACGATATAGAATTTGGAATTCAAAAAGGCATTGATATGAT
TGCTGCTTCTTTTGTTAGAAAGGCTTCTGATGTTTTGGCAATAAGAAGACTTTTAGAAGAGAATAAGGCAGAGCATATTT
TAATTATTGCCAAAATAGAGAATCGTGAAGGAGTAGAAAATATAGACGAAATTATTAAGGTTTCAGATGGAATAATGGTA
GCTAGAGGAGACTTAGGGGTTGAGATTCCTCTTGAAGAAATACCAATCGTTCAAAAGATGATTATACAAAAATGCAATAA
AGCTGGGAAACCGGTAATTACTGCAACTCAAATGTTGGACTCTATGATGAGAAATCCAAGGCCTACAAGAGCAGAAGTTA
CAGATGTAGCAAATGCTATTCTTGATGGAACAGATGCTATAATGTTATCAGGGGAGACAGCCCAAGGTAAATACCCAATA
GAGGCCTTTGAGACAATGGCTAAGATTGCAGAAAAGACAGAAGCTTACGTGGGATACAAAGATATAATCGATAGAAATAT
TGATACAAATGTTTCCATTACAAACGCTATAAGCCATGCAACTTGTACTACAGCGAGAGATATAGGTGCAGCTGCTATAA
TAACTTGTACTAAATCTGGCTATACAGCAAGAATGGTGTCAAGGTACAGACCTCAAGCTCCGATTATTGCTACTACTCCA
AGCGAAAATGTTGCAAGGAAACTCTCTATAGTGTGGGGCGTATATCCTTTAGTTACAGAAGAGGTTTCTACTACAGATGA
AATGATAGATGTGGCAATACAAAGTGCATTAACTGCAGGATTTATAAGGAATGGCGATATCGTAGTAATTTCCGCAGGAA
TTCCTGTAGCTATGGCAGGTACCACCAACATGTTGAAAGTACATATAGTAGGGGATGTTTTATTAAGAGGAATAGGTATA
GGTTCTAAAGCTACTACAGGTGCTGTATGTGTTATTAATGATATAAGTAAAGATAAAGATAAGTTCCGAGAAGGAGATAT
AATAGTTGCTGCAAAGACTGAAAGAGATTTTATGCCTCTTATAGAAAAAGCTTCGGCTATAATCACAGAAGAAGGAGGGC
TTACTTCTCACGCTGCTATTGTGGGGCTAAACCTAGGAATCCCTGTAATTGTAGGGTGCGAAGGAGCAACTTCTAAACTC
AAAGATGGCATGACTGTAACGGTTGACACCGTTAGAGGATTTGTGTATAAAGGAACTGTAAATATTAAATAA

Protein sequence :
MRRTKIVCTIGPASEDYNILRKLIEKGMNVARLNFSHGDFAEHGARIDNIKKIRQELGLPVAILLDTKGPEIRTGKFKNG
EVQLKEGQTFVITTRDVLGDETICSVSYKGLPQDVERGSRILVDDGLISLKVTDVKGEDIVCIVENSGPVKDHKGVNVPG
VKLNLPALTQKDIDDIEFGIQKGIDMIAASFVRKASDVLAIRRLLEENKAEHILIIAKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPLEEIPIVQKMIIQKCNKAGKPVITATQMLDSMMRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPI
EAFETMAKIAEKTEAYVGYKDIIDRNIDTNVSITNAISHATCTTARDIGAAAIITCTKSGYTARMVSRYRPQAPIIATTP
SENVARKLSIVWGVYPLVTEEVSTTDEMIDVAIQSALTAGFIRNGDIVVISAGIPVAMAGTTNMLKVHIVGDVLLRGIGI
GSKATTGAVCVINDISKDKDKFREGDIIVAAKTERDFMPLIEKASAIITEEGGLTSHAAIVGLNLGIPVIVGCEGATSKL
KDGMTVTVDTVRGFVYKGTVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-106 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-106 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-105 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tmath_1619 YP_003677337.1 pyruvate kinase VFG0479 Protein 1e-106 52