Gene Information

Name : M301_1070 (M301_1070)
Accession : YP_003674031.1
Strain : Methylotenera versatilis 301
Genome accession: NC_014207
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 1201233 - 1202726 bp
Length : 1494 bp
Strand : +
Note : KEGG: hna:Hneap_2372 betaine-aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase

DNA sequence :
ATGGCAGAGATTAAAATTGATTGGCATGAAAGAGCGAAAGATTTAAGAATCGATGGACGTGCTTTCATTGATGGCGAACG
TGTAGATGCACTTGATGGCAGTACCTTTGAATGCTTTTCACCGATTGACGGTCGTAAATTAGCCGATGTGGTTAATAGTA
AAGCTGCGGATGTGGACCGCGCGGTAGTTGCGGCACGTTCTGCTTTTAAAGATAGACGTTGGGCTGGTTTATCGCCTCGC
GAACGCAAGCAAACGATGATACGTTTTGCAGATTTGGTGTTAGCGCACAAAGCAGAGTTGGCATTGTTAGAAACGCTGGA
TATGGGCAAGCCTATTTCTGCAAGCTTGAGTGTAGATGTCAACTCCGCAGCAAATAGTTTGCGCTGGTTTGGTGAATCGA
TTGATAAAGTCTACGATGAGATTGCGCCAACGGCAGACCATACACTTGCAATGATTACACGCGAGCCTATCGGCGTAGTT
GGCGCTATCGTGCCATGGAATTACCCGATTTTAATGGCTTGTTGGAAGATCGCACCTGCCTTAGCTACCGGTAATAGCAT
CGTACTGAAACCTTCTGAAAAATCGCCATTAACAGCCTTAAGGCTTGGAGATTTGGCGATAGAAGCGGGTATACCAAAAG
GTGTGCTAAATGTAGTACCAGGCTTTGGCCCAGAGGCAGGTACGCCGCTTGCGATGCATCTGGATGTGGATTGCATCGCC
TTTACAGGCTCAACAGGTGTGGGTAAAAAAATCCAAATCATGGCAGGGCAAAGTAACCTCAAGCGCGCATGGTGCGAGCT
AGGTGGCAAGTCACCTAATATCGTATTTGCAGATTGCAAGGATTTGGATAAAGCAGCAGCGGCTTCTATTGGCTCAATTT
TTTATAATCAAGGAGAAAGCTGCAATGCGCCTTCGCGCTTACTGGTTGAGCGCTCAATCAAAGATGAGTTCGTCAAAAAA
CTACTAACTCATTTACCTGATTATCAGCCTGGTGATCCGTTAGATGCGAATACCACCATGGGCGCAATCGTGGATTGCGG
GCAGATGGAAAATGTACTGAAATACATTGAAAGCGGTAAATCGCAAGGTGCAAAATTGCGCGCTGGTGGTGAGCGCGTAT
TAACTGAAACAGGTGGTTTTTACATTAGCCCAACTGTATTTGATGACGTGACCAATGATATGAAAATTGCCGCTGAAGAG
ATTTTTGGCCCAGTACTTTCTATCATTGCTTTTGATACAGAACAAGAAGCAATAGCGATTGCCAATGACACAGAGTATGG
TCTTGCCGCAGCAGTTTGGACGCAAGACCTGACGCGCGCGCACATGGTGTCACGCGCCTTGCGTGCAGGTACGGTACATG
TGAATAGCTATGATGAAGACGATATCACCGTGCCTTTTGGTGGTTATAAACAATCAGGTAATGGTCGCGATAAATCCCTA
CATGCTTTGGAAAAATATACTGAGCTTAAAACGACTTGGATACGATTAATTTAA

Protein sequence :
MAEIKIDWHERAKDLRIDGRAFIDGERVDALDGSTFECFSPIDGRKLADVVNSKAADVDRAVVAARSAFKDRRWAGLSPR
ERKQTMIRFADLVLAHKAELALLETLDMGKPISASLSVDVNSAANSLRWFGESIDKVYDEIAPTADHTLAMITREPIGVV
GAIVPWNYPILMACWKIAPALATGNSIVLKPSEKSPLTALRLGDLAIEAGIPKGVLNVVPGFGPEAGTPLAMHLDVDCIA
FTGSTGVGKKIQIMAGQSNLKRAWCELGGKSPNIVFADCKDLDKAAAASIGSIFYNQGESCNAPSRLLVERSIKDEFVKK
LLTHLPDYQPGDPLDANTTMGAIVDCGQMENVLKYIESGKSQGAKLRAGGERVLTETGGFYISPTVFDDVTNDMKIAAEE
IFGPVLSIIAFDTEQEAIAIANDTEYGLAAAVWTQDLTRAHMVSRALRAGTVHVNSYDEDDITVPFGGYKQSGNGRDKSL
HALEKYTELKTTWIRLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-131 61
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-71 43
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-67 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-71 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-71 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-71 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M301_1070 YP_003674031.1 betaine-aldehyde dehydrogenase VFG0082 Protein 3e-71 43