Gene Information

Name : GC56T3_0754 (GC56T3_0754)
Accession : YP_003670376.1
Strain : Geobacillus sp. C56-T3
Genome accession: NC_014206
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 806041 - 807804 bp
Length : 1764 bp
Strand : +
Note : KEGG: gyc:GYMC61_0778 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
ATGAAGCGGAAAACGAAAATCGTCTGTACGATCGGGCCGGCAAGCGAGAGCGTAGACAAGCTCGTGCAATTGATCGAAGC
GGGGATGAACGTGGCGCGCCTCAACTTTTCGCACGGAGATCATGAGGAACACGGGCGGCGCATCGCCAACATTCGCGAGG
CGGCGAGGCGGACGGGCCAAACGGTCGCCATTTTGCTCGATACGAAAGGTCCGGAAATCCGCACGCACAATATGGAGAAC
GGCGCCATCGAACTGAAGGAAGGGGCAAAGCTCATCATTTCGATGAGCGAAGTGCTCGGCACGCCGGAAAAAATTTCTGT
CACCTATCCGGGGCTGATCGATGATGTGTCCGTTGGTTCGAAAATTTTGCTGGACGACGGGTTGATCGGCCTTGAAGTCA
ACGCGGTCGACAAGCAAGCTGGAGAAATTGTCACGACCGTCTTAAACAGCGGTGTGCTCAAAAACAAAAAAGGGGTCAAT
GTCCCCGGCGTGCGTGTCAATTTGCCGGGCATCACCGAGAAGGACCGAGCCGATATTTTATTTGGCATCCGCCAAGGCAT
CGACTTCATCGCCGCCTCGTTTGTGCGCCGGGCGTCTGATGTGCTCGAAATCCGCGAGCTGCTCGAGGCGAATGACGCCT
TACATATCCAAATTATCGCGAAAATTGAAAATGAAGAAGGCGTCGCCAACATCGATGAAATTTTGGAAGCCGCCGATGGC
CTCATGGTGGCGCGCGGCGACCTTGGCGTTGAGATTCCGGCTGAGGAAGTGCCTCTCATTCAAAAAATGCTCATTAAAAA
GTGCAACATGCTTGGCAAGCCGGTCATCACAGCGACGCAAATGCTCGACTCGATGCAGCGCAATCCGCGGCCGACGCGGG
CTGAGGCGAGCGATGTCGCCAACGCCATTTTTGACGGCACCGACGCCGTCATGCTTTCCGGAGAAACCGCAGCCGGCCAG
TATCCGGTCGAAGCGGTAAGGACGATGCACCAAATCGCGCTCCGCACCGAGCAGGCGTTGGAGCATCGCGACATTTTGTC
CCAGCGCACGAAAGAGAGCCGAACGACGATCACCGATGCCATCGGCCAATCGGTCGCCCACACGGCGCTCAATTTGGATG
TCGCGGCGATCGTGACGCCGACGGTGAGCGGAAAAACGCCGCAGATGGTGGCGAAATACCGCCCGAAAGCCCCGATCATC
GCGGTGACATCAAACGAAGCGGTCTCGCGGCGGCTGGCGCTCATTTGGGGTGTGTATACGAAAGAAGCACCGCATGTCAA
TACAACCGATGAAATGCTCGATGTGGCGGTCGACGCGGCAGTGCGCTCCGGCTTGGTGAAGCACGGCGACTTGGTCGTCA
TCACGGCCGGCGTGCCGGTCGGCGAAACGGGATCGACGAACTTAATGAAAGTGCACGTCATCAGCGACTTGCTTGCCAAA
GGGCAAGGCATCGGCCGCAAGTCGGCATTCGGCAAGGCGGTCGTCGCCAAAACGGCGGAAGAGGCGTGCCGAAAAATGGT
AGAGGGCGGCATTTTAGTCACCATCAGCACCGATGCTGATATGATTCCGGCTCTCGAAAAAGCAGCGGCGATCATTACTG
AGGAAGGCGGGTTGACGAGCCATGCGGCGGTCGTCGGCTTAAGCCTTGGCATTCCGGTCGTCGTCGGGGTGGAAAATGCC
ACAAGCTTGTTTAAAGATGGGCAAGAGATCACGGTCGATGGCGGCTTTGGCGCCGTCTACCGCGGCCATGCGAGCGTGTT
GTAA

Protein sequence :
MKRKTKIVCTIGPASESVDKLVQLIEAGMNVARLNFSHGDHEEHGRRIANIREAARRTGQTVAILLDTKGPEIRTHNMEN
GAIELKEGAKLIISMSEVLGTPEKISVTYPGLIDDVSVGSKILLDDGLIGLEVNAVDKQAGEIVTTVLNSGVLKNKKGVN
VPGVRVNLPGITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEANDALHIQIIAKIENEEGVANIDEILEAADG
LMVARGDLGVEIPAEEVPLIQKMLIKKCNMLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQ
YPVEAVRTMHQIALRTEQALEHRDILSQRTKESRTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPII
AVTSNEAVSRRLALIWGVYTKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISDLLAK
GQGIGRKSAFGKAVVAKTAEEACRKMVEGGILVTISTDADMIPALEKAAAIITEEGGLTSHAAVVGLSLGIPVVVGVENA
TSLFKDGQEITVDGGFGAVYRGHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-108 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-108 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-108 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-108 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GC56T3_0754 YP_003670376.1 pyruvate kinase VFG0479 Protein 1e-108 53