Gene Information

Name : GC56T3_2058 (GC56T3_2058)
Accession : YP_003671617.1
Strain : Geobacillus sp. C56-T3
Genome accession: NC_014206
Putative virulence/resistance : Virulence
Product : 2-hydroxymuconic semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2160247 - 2161722 bp
Length : 1476 bp
Strand : -
Note : KEGG: gyc:GYMC61_2295 2-hydroxymuconic semialdehyde dehydrogenase; TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase

DNA sequence : 
ATGAAAACAGAAGTGGTAGCCAGCGAGAAAGTGAAGGCATTTGACTGCCAACATTTCATCAACGGGCGGTTTTTGCCTTC
ACAAAGCGGCAAGATGTTTCAAAACATTAATCCCGCTACGGGGGAAGTGATCGGCACCGTCTGTGAAGGGGGGAAAGAAG
AGATTGATTTGGCGGTGGCCGCTGCAAAAAGGGCGCTTAGCGGACCGTGGAAGCGGATGACGACTGGGGAGCGGATCGCA
GTTTTGCGCCGTATCGGCGATCTCATTTTAGAGCGCAAAGAGGAACTGGCTCGCCTCGAGTCGCTCGATACGGGGAAGCC
ATACTCTCTCTCCCTCACGTTGGATATTCCGCGGGCAGCGTATAACTTCCACTTTTTCGCCGACTACTTGCGATCGGTCG
GCACGGAAGCGTATCAGACCGATGAGGTGGCCATCAACTATTCGATCCGCCGACCGGTCGGGGTCGTCGGACTGATCAAT
CCGTGGAATTTGCCGTTGCTGTTGTTGACGTGGAAGCTCGCCCCGTGTTTGGCAGCCGGGAACACGGCCGTCATCAAGCC
GGCGGAATGGACGCCGCTCACCGCAACTGTATTGGCCGAAATTTGCAAAGAAGCCGGGGTGCCGGATGGCGTTGTGAATG
TTGTTCATGGCTTTGGTCCGGATTCGGCAGGGGCGGCGTTGACTGAGCACTCGGATGTTGACGCCATTACGTTCACTGGA
GAGACAACAACTGGAAAAGTCATTATGGCGGCGGCGGCGAAATCATTGAAAAAGCTGTCTTACGAGTTGGGAGGGAAAAA
TCCGAACATCATTTTCGCCGATGCGGATTTGGACGAAGCGATCGAGACGACGTTGAAATCGAGTTTTATGAACCAAGGGG
AAGTGTGTCTGTGCGGGTCAAGAATTTATGTAGAGCGGCCGCTTTATGAACAATTTTTGCAAAAGTTTGTGGCCAAAACG
AAAGAACTCGTTGTCGGCGATCCGTTTGATCCGAGAACAAATGTCGGCGCGCTCATCAGCGAAGAGCATTACGAACGGGT
GATGAGCTACATCGAGCTGGCGAAGGAGGAAGGCGGTCGTATTTTAACCGGTGGAAAGCGGCCGGACGGCTTGGATCAAG
GATATTATCTTGAACCGACGATTATTGTCGGTGTCAACCGAAATTGCCGCATCGTCCGCGAAGAAGTGTTCGGACCGGTC
GTGACGGTCATGCCGTTTGACGAAGAAGAGGAAGTGATCGCCCAAGCGAACGACACCCACTACGGATTGAGCGCGACGAT
TTGGACGAACGATTTGCGTCGGGCGCACCGGGTGGCGGCGCGCATTGAAGCCGGAATCGTTTGGGTCAATACGTGGTTTT
TACGTGATTTGCGCACACCGTTTGGCGGTATGAAACAAAGCGGCATCGGGCGCGAAGGCGGCATGCATAGCTTTGAGTTT
TATACAGAATTGACGAACATTTGCATTAAGCTTTAG

Protein sequence : 
MKTEVVASEKVKAFDCQHFINGRFLPSQSGKMFQNINPATGEVIGTVCEGGKEEIDLAVAAAKRALSGPWKRMTTGERIA
VLRRIGDLILERKEELARLESLDTGKPYSLSLTLDIPRAAYNFHFFADYLRSVGTEAYQTDEVAINYSIRRPVGVVGLIN
PWNLPLLLLTWKLAPCLAAGNTAVIKPAEWTPLTATVLAEICKEAGVPDGVVNVVHGFGPDSAGAALTEHSDVDAITFTG
ETTTGKVIMAAAAKSLKKLSYELGGKNPNIIFADADLDEAIETTLKSSFMNQGEVCLCGSRIYVERPLYEQFLQKFVAKT
KELVVGDPFDPRTNVGALISEEHYERVMSYIELAKEEGGRILTGGKRPDGLDQGYYLEPTIIVGVNRNCRIVREEVFGPV
VTVMPFDEEEEVIAQANDTHYGLSATIWTNDLRRAHRVAARIEAGIVWVNTWFLRDLRTPFGGMKQSGIGREGGMHSFEF
YTELTNICIKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-85 47
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-65 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-66 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 9e-68 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 9e-68 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 9e-68 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GC56T3_2058 YP_003671617.1 2-hydroxymuconic semialdehyde dehydrogenase VFG0082 Protein 2e-66 42