Gene Information

Name : bacE (BMB171_C2075)
Accession : YP_003664608.1
Strain : Bacillus thuringiensis BMB171
Genome accession: NC_014171
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 2206349 - 2207965 bp
Length : 1617 bp
Strand : +
Note : -

DNA sequence : 
ATGCTAGTAGGTTATACAGAATGGCCAAAAGAATTTGCCGATCGTTACCGAGAAGAAGGATGTTGGCTTGGTGAAACATT
TGGAGGAGTGTTAAGAGAGCGGGCTGAGAAATATGGAGATCAAATCGCGGTTGTAAGTGGTAAGAAGCATATAACATATA
GTGAACTTAATAAAAAGGTAGATCGTTTAGCAGCAGGTTTACTGAATTTAGGAATAAAGAAAGAGGACAGAGTTGTAATC
CAGTTACCTAACATTATCGAGTTTTTCGAAATATGTTTTGCACTATTTCGAATTGGAGCGCTTCCTGTCTTTGCACTGCC
GTCACATCGAAGCAGTGAAATTAGTTATTTTTGTGATTTTGGCGAGGCGAGCGCTTACGTTATTTCAGATAAGGCTCTCG
GTTTTGATTATCGAAAACTAGCAAGAGAAGTGAAAGAGAAAGTGCCAAATTTACAACATGTAATTGTAGTGGGAGAAGAA
GAAGAGTTTGTGAACATAAATGATCTGTATATGGATCCCGTCTCATTACCAGAAGTTCAGCCAAGTGATGTTGCGTTTCT
CCAATTATCAGGAGGCACAACAGGTCTTTCTAAATTAATTCCTAGAACACATGATGACTATATTTATAGTTTGCGTGTTA
GCGCTAAAATTTGTAATTTGAATGCAGAAAGCGTCTATATGGCAGTTCTTCCAGTAGCACACAATTACCCAATGAGTTCT
CCAGGGACATTTGGAACTTTCTATGCGGGTGGAAAAGTGGTATTGGCAACTGGTGGTAGTCCAGATGAGGCATTTGCTCT
TATCGAAAAAGAAAAAGTTACAATTACAGCGCTCGTTCCGCCATTAGCAATGATTTGGCTTGATGCTGCATCTTCTCGTA
ATACCGATTTATCGAGCCTAGAGGTTATTCAAGTAGGTGGTGCTAAGTTTAGTGCTGAGGTAGCAAGACGTATACGCCCT
ACATTTGGATGTACGTTACAGCAAGTATTCGGTATGGCGGAAGGATTAGTGAACTATACAAGATTAGACGATCCGGAAGA
AATTATTATTCATACACAAGGTAGACCAATGTCTGCACTCGATGAAGTACGAGTTGTTGATGAAAATGACAACGATGTAC
AACCGGGCGAAGTAGGTAGTTTATTAACACGAGGTCCATATACAATTCGTGGTTACTATAAAGCCGAAGAGCATAATGCA
CGATCATTTACAAAGGATGGATTTTATCGCACAGGTGATCTTGTAAAAGTAAATGAACAAGGATACATCATTGTAGAAGG
AAGAGATAAAGATCAAATTAACCGTGGTGGTGAGAAAGTTGCTGCAGAAGAAGTTGAAAATCATCTATTAGCACACGATG
CGGTCCATGACGTAGCAATTGTATCTATGCCTGACGATTATTTAGGTGAACGCACCTGTGCTTTTGTTATAGCTCGCGGA
CAAGTTCCGGCAGTAAGTGAATTAAAAATGTTTTTAAGAGAACGTGGTATAGCGGCTTATAAAATTCCAGATCGAATTGA
ATTTATTGAATCATTTCCGCAAACAGGAGTCGGAAAAGTCAGCAAAAAAGAACTACGTAAAGTCATTGCTGAAAAACTTA
TTACAGTAAAACAATAA

Protein sequence : 
MLVGYTEWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVSGKKHITYSELNKKVDRLAAGLLNLGIKKEDRVVI
QLPNIIEFFEICFALFRIGALPVFALPSHRSSEISYFCDFGEASAYVISDKALGFDYRKLAREVKEKVPNLQHVIVVGEE
EEFVNINDLYMDPVSLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAKICNLNAESVYMAVLPVAHNYPMSS
PGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSRNTDLSSLEVIQVGGAKFSAEVARRIRP
TFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQGRPMSALDEVRVVDENDNDVQPGEVGSLLTRGPYTIRGYYKAEEHNA
RSFTKDGFYRTGDLVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTCAFVIARG
QVPAVSELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKELRKVIAEKLITVKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-119 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 9e-119 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-119 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 9e-119 50
ybtE CAA21394.1 - Virulence HPI Protein 9e-119 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 7e-119 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-118 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-119 50
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-119 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
bacE YP_003664608.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 2e-136 52
bacE YP_003664608.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 1e-112 47
bacE YP_003664608.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 7e-111 45