Gene Information

Name : Srot_0739 (Srot_0739)
Accession : YP_003658050.1
Strain : Segniliparus rotundus DSM 44985
Genome accession: NC_014168
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 725718 - 727235 bp
Length : 1518 bp
Strand : -
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: rop:ROP_23290 2,3-dihydroxybenzoate-AMP ligase

DNA sequence :
ATGGGAGGCGATGTGAACACGAGCGCGCTCGGAGCGCTCCTCTCCCGGGCCGTCGAGCGCTGGCCGGATCGTGTCGCAGT
GGCGCAAGGCGAGCGGACGCTCACCTACCAAGAACTCGAAGACGAGACACAGGCTTTCGCCAGAGGCCTCGCCGCGTTCG
GTTTGGAGCCTGGCGAGAAAGCGCTCCTCCAAGTTCCGAATTCGCCTGAATTCCTGATCGCGCTGTTCGGCTCCCTCGCC
GCAGGCGTGGTGCCCGTCATGTGCTTGCCCGGACACCGCGACGCCGAGCTCAACCATTTCACCCAGATCTGCGGGGCAGT
CGCGCACCTGACCACACCGCAGATCGCCAAGCTGGTCTCGCCCCCGGTGCGCGCCCTCACCATCGACGTGGTGCTCGCGG
CAGGCCAGGCGTACGCCGAATCGAACAGCGCGCCGGCGATCGACCCGGCGGCGCCTGCGCTCCTCCTGGTGTCGGGAGGC
ACCACGGGGCTGCCGAAACTCATCCCGCGCACCCATCGGGACTACTGGTACAACCTGACTGCGGCAGCGCAGGCCTGCGA
GCTGTCCGAGTCGGACGTGTATCTCGCGGCGCTGCCCGTCGCGCACAATTTCCCGCTCGCCTGCCCTGGGGTCCTCGGCG
CCATCAGCCTCGGCGGCACGACGGTTTTCGCCTCCGACCCCAGCCCCGAGGCGGCGTTCGCCGCAATCGAGCAGCACGGC
GTCACGGTCACCGCCCTGACCCCGCCGCTCGCCCAGCTGTGGGCGGCGGCAGCCGAATGGGAGTCCTCCGACTTGAGTTC
GCTGCGACTTTTGCAGGTGGGCGGCGCGAAACTCGAATCCGAACAGGCCAGGGAGATCCAAAACGCCCTCGGAGCCACGC
TGCAGCAGGTGTTCGGCATGGCCGAAGGCCTGATCTGCTGCACCCGGTCGGACGACCCCGAGGAACTCGTTTTCACCACG
CAGGGGCGCCCTATGTCCGACGAGGACGAGGTGCGCTTGGTGGATGAAGAAGGGGCGCAGGTTCCTGAGGGCGAGATCGG
CGAGCTCGAAGTGCGCGGCCCGTACACGATCACTGGCTACTACAACGCGCCGGAAGCGAACGCGCGCTCGTTCACGCCGG
ACGGCTTCTATCGCAGCGGCGACCTCGCCAAGCGGCTTCCGTCCGGGCATCTTGTCGTGGTCGGGCGGGTCAAAGATGTG
ATTAACCGGGGCGGCGAGACGATTTCCGCCGAAGAGATCGAAGGGCATCTGCTCGCGCACCCCCAGATCAGCGCCGCGGC
GGCGGTCCCGTGCCCGGACAAGTACTTGGGCGAGAAGGTCTGCGCGGCAGTCGTGCTGCGCCCGGAAGACGCCGGCGCGG
GCCAGCTGGAACTCCCGCAGTTGCGGGCCTTCCTCGCCGAACGAGGCTTGTCCGTCGAGAAACAACCCGATGTTCTGTTG
CGACTGCCTTCGCTGCCCATGACAGCGGTCGGCAAAGTGGACAAGCGCGCCATAGCGGCCCAGCTCGCGCACGCCTGA

Protein sequence :
MGGDVNTSALGALLSRAVERWPDRVAVAQGERTLTYQELEDETQAFARGLAAFGLEPGEKALLQVPNSPEFLIALFGSLA
AGVVPVMCLPGHRDAELNHFTQICGAVAHLTTPQIAKLVSPPVRALTIDVVLAAGQAYAESNSAPAIDPAAPALLLVSGG
TTGLPKLIPRTHRDYWYNLTAAAQACELSESDVYLAALPVAHNFPLACPGVLGAISLGGTTVFASDPSPEAAFAAIEQHG
VTVTALTPPLAQLWAAAAEWESSDLSSLRLLQVGGAKLESEQAREIQNALGATLQQVFGMAEGLICCTRSDDPEELVFTT
QGRPMSDEDEVRLVDEEGAQVPEGEIGELEVRGPYTITGYYNAPEANARSFTPDGFYRSGDLAKRLPSGHLVVVGRVKDV
INRGGETISAEEIEGHLLAHPQISAAAAVPCPDKYLGEKVCAAVVLRPEDAGAGQLELPQLRAFLAERGLSVEKQPDVLL
RLPSLPMTAVGKVDKRAIAAQLAHA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-78 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 8e-79 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-78 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-78 43
ybtE CAA21394.1 - Virulence HPI Protein 4e-78 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 3e-78 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 4e-78 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-78 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 4e-78 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Srot_0739 YP_003658050.1 AMP-dependent synthetase and ligase VFG1817 Protein 1e-107 52
Srot_0739 YP_003658050.1 AMP-dependent synthetase and ligase VFG0168 Protein 3e-82 45
Srot_0739 YP_003658050.1 AMP-dependent synthetase and ligase VFG0932 Protein 8e-73 42