Gene Information

Name : Srot_1979 (Srot_1979)
Accession : YP_003659267.1
Strain : Segniliparus rotundus DSM 44985
Genome accession: NC_014168
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1998504 - 1999664 bp
Length : 1161 bp
Strand : -
Note : KEGG: mav:MAV_1203 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein

DNA sequence :
GTGAGCGCACAGGATTTCTCCCAACAAGGTTTCTCCACTCGGGTCATCCATCCCGACCACGAATTGGACCCCGCATTCGG
CGCGGTGAACGCGCCGATCTACGCGACTTCCACCTTCGCCCAGGACGGTGTGGGCGGCCTCAAAGGAGGGTACGAGTACT
CGCGCAGCGCCAACCCGACTCGCACCGCGCTCGAGAAGACGCTCGCGGCGAGCGAGACGGCGCAGCACGCCAGGGCGTTC
AGCTCGGGCTTGGCCGCCACGGACGCGGTGCTGCGCGCGCTTGTGAAGCCTGGCGAGCACCTTGTCATCCCGCACGACGC
GTACGGGGGGACCTTCCGGCTCGTGGACAAGATCCTGCGCCCGTGGGGCGTCGCGTACTCCATTGCCAAATCCCATGAAC
CGCAGGCCTTCGTGGACCAGATCACCCCGCAGACCAAGGCGATCTGGGTGGAGACGCCGAGCAATCCGCTGCTCTCGGTC
ACTGACATCGCCGCGCTGGCCGAAGCCGCGCGCTCGGCGCAGGTCGCGCTGCTTGTGGACAACACGTTCGCATCGCCCTA
TTTGCAGCGCCCATTGGAGCTCGGGGCGCATGCGGTGGTCCACTCCGCCACGAAATACCTTGGTGGGCACTCCGACGTCA
TCGGCGGGGCGGTGGTCACGAATGATTCGGAGCTCGACGCCGCCGTGGGATTTTTGCAGAACGGCTCCGGCGCGGTGCCG
AGCCCGTTCGACGCGTTCCTGATTCGCCGGGGCATGCTCACGCTCGGCGTCCGGGTCCAGCGTCAGAGCGAGAGCGCGCT
CAGGATCGCCGAGCACCTTGCCGATCATCCGAAAGTCGTCAAAGTGCTCTATCCGGGCCTTGCGGGCGACCCCGGCCACC
ATATCGCCGCCGCGCAGATGCGCGGCGGATTCGGCGGGATGCTCTCAGTCCGCTTGCGCGGCGGGGAACAGGCCGCGCTC
GACCTGTGCGCCCGCGTCAAGGTCTTCACCCTCGGCGAGTCGTTGGGCGGCGTTGAATCGCTCATCGAGCACCCCGCGCG
GATGACCCATGCCTCCGTGGTGGGGTCGGATCTGGAGGTGCCGACTGACCTGGTGCGGCTCTCTGTCGGCCTTGAGGACG
TCGGGGACCTGATCGCCGATCTCGACGAGGCATTGGGTTAG

Protein sequence :
MSAQDFSQQGFSTRVIHPDHELDPAFGAVNAPIYATSTFAQDGVGGLKGGYEYSRSANPTRTALEKTLAASETAQHARAF
SSGLAATDAVLRALVKPGEHLVIPHDAYGGTFRLVDKILRPWGVAYSIAKSHEPQAFVDQITPQTKAIWVETPSNPLLSV
TDIAALAEAARSAQVALLVDNTFASPYLQRPLELGAHAVVHSATKYLGGHSDVIGGAVVTNDSELDAAVGFLQNGSGAVP
SPFDAFLIRRGMLTLGVRVQRQSESALRIAEHLADHPKVVKVLYPGLAGDPGHHIAAAQMRGGFGGMLSVRLRGGEQAAL
DLCARVKVFTLGESLGGVESLIEHPARMTHASVVGSDLEVPTDLVRLSVGLEDVGDLIADLDEALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-69 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-70 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Srot_1979 YP_003659267.1 cystathionine gamma-synthase BAC0207 Protein 5e-55 41