Gene Information

Name : Tbis_0364 (Tbis_0364)
Accession : YP_003650987.1
Strain : Thermobispora bispora DSM 43833
Genome accession: NC_014165
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 412221 - 413657 bp
Length : 1437 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: scl:sce5007 putative aldehyde dehydrogenase (NAD(+))

DNA sequence : 
ATGTTCGAGTACGCGCCCGCGCCCGAATCGCGGGACATCGTCGATATCCAGCCGTCGTACGGCTTGTTCATCAACGGGGA
GTGGGTCGAACCCCACTCCGAGGAGCGGCACCCGACCGTCAACCCGGCCACCGAGGAGCCGTTGTCCGAGATCGCCTGGG
CGGACGAGGCCGACGTGGACCGGGCGGTCGAGACCGCGCGCAAGGCGTTCGTCACCTGGTCGGCGATGCGCGGCGCCGAA
CGGGCGAAGTACCTCTTCCGGATCGCCCGGATCATCCAGGAACGAGCGCGCGAGCTCGCCGTGCTGGAGACCCTCGACAA
CGGCAAGCCGATCCGCGAGTCGCGCGACGTGGACCTGCCGCTGGTCGCAGCCCACTTCTTCTACTACGCGGGCTGGGCGG
ACAAGCTCGCCTACGCCGGGCTCGGCCGGCCCGGGAGGGAGCCCCGGCCCATCGGCGTGGCCGGGCAGGTGATCCCATGG
AACTTCCCGCTGCTCATGCTGGCGTGGAAGGTCGCCCCCGCGCTCGCCTGCGGCAACACGGTCGTGCTCAAGCCCGCCGA
GACCACCCCGCTCACCGCGCTCGCCTTCGCCGACATCTGCCGGCAGGCCGACCTGCCCCCCGGCGTGGTCAACATCGTCA
CCGGTGCCGGGGAGACCGGAGCGGCGCTGGTGCGCCACCCCGGCGTGGACAAGGTCGCGTTCACCGGCTCGACCGAGGTC
GGCAAGCTCATCGCCAAGGCCGTGGCGGGGACGGGCAAGCGGCTCACCCTGGAGCTCGGGGGCAAGGCCGCCAACATCGT
GTTCGACGACGCGCCCATCGACCAGGCGGTCGAGGGGATCGTCAACGGCATCTTCTTCAACCAGGGCCACGTGTGCTGCG
CGGGGTCCCGGCTGCTCGTCCAGGAGTCGATCGCCGATGAGCTGATCGAGGCGCTCAAGCGGCGGATCGCCCTGCTCCGG
GTCGGCGACCCGCTCGACAAGAACACCGACATCGGCGCGATCAACTCGGCCGAGCAGCTCGCCAAGATCCGTGAGCTCGC
CGAGTCCGGGGAGGCGGAGGGCGCCGAGCGGTGGTCGCCGCCGTGCACGCTCCCGGACCGGGGGTACTGGTTCCCGCCGA
CGGTGTTCACCAACGTGGCGCAGTCGCACCGCATCGCGCGGGAGGAGATCTTCGGCCCGGTGCTCTCCGTGCTCACGTTC
CGCACCCCCGCCGAGGCGGTGGAGAAGGCGAACAACACGCCGTACGGCCTCTCCGCTGGGGTGTGGACGGAGAAGGGCTC
GCTCATGCTGTGGATGGCGTCCCGGCTCCGCGCCGGGGTGGTCTGGTCGAACACGTACAACCGGTTCGACCCGGCGTCGC
CGTTCGGCGGGTACAAGGAGTCGGGTTACGGCCGCGAAGGTGGTCGGCACGGTCTGGAGGAGTACCTTGCGTTGTGA

Protein sequence : 
MFEYAPAPESRDIVDIQPSYGLFINGEWVEPHSEERHPTVNPATEEPLSEIAWADEADVDRAVETARKAFVTWSAMRGAE
RAKYLFRIARIIQERARELAVLETLDNGKPIRESRDVDLPLVAAHFFYYAGWADKLAYAGLGRPGREPRPIGVAGQVIPW
NFPLLMLAWKVAPALACGNTVVLKPAETTPLTALAFADICRQADLPPGVVNIVTGAGETGAALVRHPGVDKVAFTGSTEV
GKLIAKAVAGTGKRLTLELGGKAANIVFDDAPIDQAVEGIVNGIFFNQGHVCCAGSRLLVQESIADELIEALKRRIALLR
VGDPLDKNTDIGAINSAEQLAKIRELAESGEAEGAERWSPPCTLPDRGYWFPPTVFTNVAQSHRIAREEIFGPVLSVLTF
RTPAEAVEKANNTPYGLSAGVWTEKGSLMLWMASRLRAGVVWSNTYNRFDPASPFGGYKESGYGREGGRHGLEEYLAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 2e-54 45
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 3e-54 44
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 5e-54 44
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 5e-54 44
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 5e-54 44
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 3e-54 44
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 3e-54 44
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 6e-54 44
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 6e-54 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-69 43
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-63 43
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-74 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-74 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-74 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tbis_0364 YP_003650987.1 betaine-aldehyde dehydrogenase VFG0082 Protein 1e-69 43