Gene Information

Name : Tbis_0243 (Tbis_0243)
Accession : YP_003650868.1
Strain : Thermobispora bispora DSM 43833
Genome accession: NC_014165
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 285741 - 288326 bp
Length : 2586 bp
Strand : -
Note : KEGG: ade:Adeh_0385 AAA ATPase, ClpA/B; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase

DNA sequence :
ATGGAATACAAGCTCACCCAGAAAAGCCAAGAGGCACTCTCCGCGGCCGTGCGGCGGGCCACCGCCGACGGTAACCCCGA
GGTGATGCCCGCCCACCTGCTGGCGGCGCTGCTCGCCCAGACGGGTGGCATCGCGGTGCCGCTGCTGGAGGCGGTGGGCG
CGGACTGGAGGCGGCTGCGCGCCCGCAACGAGGAGCTCCTCGGCCGGCTGCCCAAGGCGCGCGGGGCCACGGTGAGCGCT
CCGTCGACCTCCCGCCAGCTCATCTCCGTGCTCAACACCGCGGCCGAGCGGGCCAAGCGGCTCGAGGACGAGTACGTCTC
GACCGAGCACCTCATGGTCGGGCTCGCCTCGGACGGCGGCCAGGTGGCCGAGCTCCTCCGGCAGGAGGGCGCCACGGCCG
ACGCGCTGCTCGAGGCGTTCGAGAAGGTGCGCGGGCACGCCCGGGTCACCAGCGAGACCCCGGAGGACACCTACCAGGCG
CTGGAGAAGTACGGCGTCGACCTCACCGAGCGGGCGCGGGCCGGCAAGCTCGACCCGGTCATCGGGCGGGACGCCGAGAT
CCGCCGGGTGATCCAGGTGCTCTCCCGCCGCACCAAGAACAACCCGGTGCTGATCGGGGAGCCGGGCGTCGGCAAGACGG
CCGTGGTCGAGGGCCTCGCCCAGCGGATCGTCGCCGGGGACGTGCCGGAGACCCTGAAGAACAAGCGCCTGGTCGCGCTC
GACCTCGGCGCGATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGGCTCAAGGCCGTGCTCAACGAGATCAA
GGCGAGCGACGGCCAGATCATCACGTTCATCGACGAGCTGCACACGGTGGTCGGCGCCGGCGCGGCCGAGGGCGCGATGG
ACGCCGGCAACATGCTCAAGCCCATGCTCGCCCGCGGTGAGCTGCGGATGATCGGCGCCACCACGCTCGACGAGTACCGG
GAGCGCATCGAGAAGGACCCGGCCCTGGAGCGCAGGTTCCAGCAGATCTACGTCGGCGAGCCGTCCGTCGAGGACACCAT
CGCGATCCTGCGCGGGCTCAAGGGCCGCTACGAGGCGCACCACCAGGTCCAGATCTCCGACAGCGCCCTCGTGGCCGCGG
CCACGCTCTCCGACCGGTACATCACGGCGCGGTTCCTGCCCGACAAGGCGATCGACCTCGTCGACGAGGCGATGTCCCGG
CTGCGCATGGAGATCGACTCCCGGCCGGTGGAGATCGACCAGCTCCAGCGGAGCGTGGACCGGCTCAAGATGGAGGAGCT
CGCGCTCGCCAAGGAGACCGACGCGGCGAGCCGGGAGCGGCTCGAGAAGCTCCGCGAGGAGCTCGCCAACAAGCAGGAGG
AGCTCAACGCGCTGATCAGCCGGTGGGAGCGGGAGAAGGCCGGGCTGAACAAGGTCGGCGAGCTGAAGAAGCAGCTCGAC
GAGGCCAGGAGCGCGGCCGAGCGCGCCCAGCGCGACGGCGACTTCGAGACCGCCTCCCGCCTCATGTACGGCGAGATCCC
GCGGCTGGAGAAGGAGCTCAGCGAGGCCTCCAAGATCGCCGAGGCGGCGGAGACCGCGCCGATGGTGAAGGAGGAGGTCG
GCCCGGACGAGATCGCCGAGGTGGTCTCGGCGTGGACCGGCATCCCGGCCGGCCGGCTGCTGGAGGGCGAGAGCGCCAAG
CTGCTCCGGATGGAGGACGAGCTGGGCAAGCGCCTGATCGGCCAGCACCGGGCCGTCCAGGCCGTCTCGGACGCGGTACG
GCGGGCCCGGGCCGGCATCTCCGACCCCGATCGGCCGACCGGTTCGTTCATGTTCCTCGGCCCGACCGGCGTCGGCAAGA
CCGAGCTGGCCAAGGCGCTCGCGGAGTTCCTCTTCGACGACGAGCGCGCCATGACGCGCATCGACATGAGCGAGTACAGC
GAGAAGCACACCGTGGCCCGGCTGGTCGGTGCGCCGCCCGGCTACGTCGGGTACGAGGAGGGCGGTCAGCTCACCGAGGC
CGTCCGCCGCCGGCCGTACACGGTGGTGCTGCTCGACGAGATCGAGAAGGCCCACCCGGAGGTCTTCGACATCCTGCTCC
AGGTCCTCGACGACGGCCGGCTCACCGACGGTCAGGGCCGCACGGTCGACTTCCGGAACACGATCCTGATCCTGACCTCG
AACCTCGGCTCGCAGTACCTCGTCGATCCGCAGCTGGATCAGGCGGCCAAGCACGAGGCCGTGATGAACGCCGTGCGGGC
GGCGTTCAAGCCGGAGTTCCTCAACCGGCTCGACGACATCATCATCTTCGACCCGCTCGGCACCGAGGAACTGACCAAGA
TCGTGGACCTGCAGGTCGCGCGGCTCGCCCGCCGGCTCTCCGAGCGGCGGCTCACGCTCACCGTGACGCCCGCCGCCCGG
GAGTGGCTCGCGCTGACCGGGTATGACCCGATGTACGGCGCCCGCCCGCTGCGCCGGCTGATCCAGACGGCGATCGGGGA
CCAGCTCGCCAAGGAGCTGCTCGCGGGCAACATCCGGGACGGCGATGAGGTGATCGTTGATCTGGATTCGGCAAGGGATG
CGCTGACCATCCGGCCCGCTCGGTAA

Protein sequence :
MEYKLTQKSQEALSAAVRRATADGNPEVMPAHLLAALLAQTGGIAVPLLEAVGADWRRLRARNEELLGRLPKARGATVSA
PSTSRQLISVLNTAAERAKRLEDEYVSTEHLMVGLASDGGQVAELLRQEGATADALLEAFEKVRGHARVTSETPEDTYQA
LEKYGVDLTERARAGKLDPVIGRDAEIRRVIQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVAGDVPETLKNKRLVAL
DLGAMVAGAKYRGEFEERLKAVLNEIKASDGQIITFIDELHTVVGAGAAEGAMDAGNMLKPMLARGELRMIGATTLDEYR
ERIEKDPALERRFQQIYVGEPSVEDTIAILRGLKGRYEAHHQVQISDSALVAAATLSDRYITARFLPDKAIDLVDEAMSR
LRMEIDSRPVEIDQLQRSVDRLKMEELALAKETDAASRERLEKLREELANKQEELNALISRWEREKAGLNKVGELKKQLD
EARSAAERAQRDGDFETASRLMYGEIPRLEKELSEASKIAEAAETAPMVKEEVGPDEIAEVVSAWTGIPAGRLLEGESAK
LLRMEDELGKRLIGQHRAVQAVSDAVRRARAGISDPDRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMTRIDMSEYS
EKHTVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLLDEIEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILILTS
NLGSQYLVDPQLDQAAKHEAVMNAVRAAFKPEFLNRLDDIIIFDPLGTEELTKIVDLQVARLARRLSERRLTLTVTPAAR
EWLALTGYDPMYGARPLRRLIQTAIGDQLAKELLAGNIRDGDEVIVDLDSARDALTIRPAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-101 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tbis_0243 YP_003650868.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-118 47
Tbis_0243 YP_003650868.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-106 44