Gene Information

Name : Tpau_0573 (Tpau_0573)
Accession : YP_003645552.1
Strain : Tsukamurella paurometabola DSM 20162
Genome accession: NC_014158
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 600786 - 603353 bp
Length : 2568 bp
Strand : +
Note : KEGG: nfa:nfa4150 Clp protease; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; ATPase AAA; UvrB/UvrC protein; ATPase AAA; Clp domain protein; SMART: ATPase AAA

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCTCGTCGCGTCGTCGTCCTGGCGCAAGAAGAAGCCAGGATGCTCAATCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGCCTCATCCACGAGGGTGAGGGCGTGGCCGCGAAGGCTCTCGAGTCGCTGGGCA
TCTCCCTGGAGGGTGTGCGCAGCCAGGTCGAGGAGATCGTCGGGCAGGGGCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACGCCGCGTGCCAAGAAGGTCCTTGAGCTCTCGCTCCGCGAGGCGCTGCAGCTGGGCCACAACTACATCGGTACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTGGCCGCCCAGGTCCTGGTGAAGCTGGGCGCCGATCTCAACCGCG
TGCGCCAGCAGGTCATCCAGCTGCTGTCGGGCTATCAGGGCAAGGAGGGCGGCGAGCCCGCCGGCGCCGGTGCCCGCGCC
TCCAGCGGTGGCGAGGCCGGCACCCCGTCGACCTCTCTGGTCCTCGACCAGTTCGGCCGGAACCTGACCGCCGCGGCGGC
CCAGGGCAAGCTGGACCCGGTGATCGGCCGGTCCAAAGAGATCGAGCGCATCATGCAGGTGCTCTCCCGGCGCACCAAGA
ACAACCCGGTGCTGATCGGTGAGCCCGGCGTCGGTAAGACCGCCGTGGTCGAGGGCCTCGCGCAGGCCATCGTCAACGGC
AACGTTCCGGAGACGCTCAAGGACAAGCAGCTCTACACCCTGGACCTCGGGTCCCTGGTGGCAGGCTCGCGCTACCGCGG
TGACTTCGAGGAGCGCCTGCGCAAGGTGCTCAAGGAGATCGACACGCGCGGCGACATCATCCTGTTCATCGACGAGCTGC
ACACGCTCGTGGGAGCCGGAGCCGCGGAAGGCGCCATTGACGCCGCGTCGATCCTCAAGCCCAAGCTCGCCCGTGGTGAA
CTGCAGACCATCGGCGCCACCACGCTCGACGAGTACCGCAAGTACATCGAGAAGGATGCCGCCCTGGAGCGTCGGTTCCA
GCCCGTCCAGGTGGGCGAGCCGAGCGTCGAGCACGCCATCGAGATCCTCAAGGGCCTGCGCGACCGGTACGAGGCGCACC
ACCGCATCTCGATCACCGACAGCGCGCTGGTGGCCGCCGCCACCCTGGCGGACCGGTACATCAACGACCGGTTCCTGCCG
GACAAGGCGATCGACCTCATCGACGAGGCGGGCGCGCGCATGCGCATCCGCCGGATGACCGCTCCGCCGGACCTGCGGCA
GTTCGACGACAAGATCGCCGACGCCCGCCGCGAGAAGGAATCGGCGATCGACGAGCAGGACTTCGAGAAGGCCGCGTCGC
TGCGCGATAAGGAGAAGCAGCTCATCGGTGAGCGCGCCGAGCGCGAGAAGCAGTGGCGCGCCGGTGATCTCGACGTGGTT
GCCGAGGTCGACGAGGAACAGATCGCGGAGGTCCTGGGCAACTGGACCGGTATCCCGGTGTTCAAGCTCACCGAGGAGGA
GACCACCCGTCTGCTCCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCGGTGTCCA
AGGCGATCCGTCGCACTCGCGCCGGCCTGAAGGATCCGAAGCGCCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGT
GTGGGTAAGACGGAGCTGTCGAAGGCGCTGGCGAACTTCCTGTTCGGCGAGGACGATGCGCTCATCCAGATCGACATGGG
CGAGTTCCACGACCGGTTCACCGCCTCGCGCCTGTTCGGCGCCCCTCCCGGGTACGTGGGCTACGAGGAGGGCGGCCAGC
TCACCGAGAAGGTGCGCCGCAAGCCGTTCTCCGTGGTGTTGTTCGACGAGATCGAGAAGGCGCACAGCGAGATCTACAAC
ACGCTGCTGCAGGTGCTGGAGGACGGTCGTCTCACCGACGGCCAGGGCCGCACCGTGGACTTCAAGAACACGGTCCTGAT
CTTCACGTCGAACCTCGGTACGGGCGATATCTCGAAGGCCGTCGGCCTGGGCTTCACCCAGGGCGATTCCGACGGGGCGA
ACTACGACCGGATGAAGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACGAC
ATCGTCGTCTTCCACCAGCTGACCCAGCCGCAGATCATCGAGATGGTCGATCTGATGCTCAGCCGTGTGGCCGTGGCCCT
GAAGAACAAGGACATGGAGATCGAGGTCACCGATCAGGCCAAGTCGCTGCTCGCCAAGCGCGGCTTCGACCCGGTGCTCG
GTGCCCGTCCGCTGCGTCGCACCATCCAGCGGGAGATCGAGGACAACCTGTCCGAGAAGATCCTGTTCGGCGAGCTCGGC
CCCGGCCAGATCGTCGTGGTCGACGTCGAGGGCTGGGACGGCGAGGGCAAGGGGGAGGACGCCAAGTTCGTCTTCTCCGG
TAAGCCCAAGCCGGCGCCGGTCGAGTCCGAATCCTCCGACGATGCCGTGCCCGCGCTGGCCGGCGAGTCGCCGAGCGAGT
CGGCGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEGVRSQVEEIVGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGKEGGEPAGAGARA
SSGGEAGTPSTSLVLDQFGRNLTAAAAQGKLDPVIGRSKEIERIMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVNG
NVPETLKDKQLYTLDLGSLVAGSRYRGDFEERLRKVLKEIDTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGE
LQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPSVEHAIEILKGLRDRYEAHHRISITDSALVAAATLADRYINDRFLP
DKAIDLIDEAGARMRIRRMTAPPDLRQFDDKIADARREKESAIDEQDFEKAASLRDKEKQLIGERAEREKQWRAGDLDVV
AEVDEEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSG
VGKTELSKALANFLFGEDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHSEIYN
TLLQVLEDGRLTDGQGRTVDFKNTVLIFTSNLGTGDISKAVGLGFTQGDSDGANYDRMKQKVNDELKKHFRPEFLNRIDD
IVVFHQLTQPQIIEMVDLMLSRVAVALKNKDMEIEVTDQAKSLLAKRGFDPVLGARPLRRTIQREIEDNLSEKILFGELG
PGQIVVVDVEGWDGEGKGEDAKFVFSGKPKPAPVESESSDDAVPALAGESPSESA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 80

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tpau_0573 YP_003645552.1 ATPase AAA VFG0079 Protein 0.0 60
Tpau_0573 YP_003645552.1 ATPase AAA VFG0080 Protein 1e-144 50