Gene Information

Name : Tpau_0494 (Tpau_0494)
Accession : YP_003645474.1
Strain : Tsukamurella paurometabola DSM 20162
Genome accession: NC_014158
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 522331 - 524871 bp
Length : 2541 bp
Strand : +
Note : TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; ATPase AAA; Torsin; ATPase AAA; Clp domain protein; KEGG: rha:RHA1_ro05514 ATP-binding subunit of heat shock protein ClpB; SMART: ATPase AAA

DNA sequence :
GTGGATTCGTTCAACCCCACTACCAAGACGCAGGCCGCGCTCACGTCGGCGCTGCAGGCGGCGTCCGCCGCGGGCAACCC
GGAGATTTCTCCGGCGCACCTGCTGGTGGCGCTGCTGGACCAGACCGACGGTATCGCCGCGCCGCTGCTCAAGGCAGTGG
GCGTCGATCCCGTCACGGTGCGCAACCGTGCACAGGAGCTCGTGGACCGCAAGCCCAAGGCCAGCGGTTCCACCACCCAG
CCGCAGCTGAGCCGCGAATCACTCGCGTCGATCACGGCCGCACAGAAGCTCGCCACCGAGATGGGCGACCAGTACGTCTC
CACCGAGCACGTGCTCTACGGTCTGTCCGAGGCCGCCCAGGTTCTCGGCAACGCCGGCGCCACCCCGCAGGCGATCCAGG
AGGCCTTCACCGCCGTCCGCGGCAGCGCGAAGGTCACCTCGCAGGATCCCGAGGGTCAGTACCAGGCGCTGGAGAAGTAC
TCGACCGATCTCACCGCGCGGGCCCGCGAGGGCAAGCTCGACCCGGTGATCGGGCGCGACAATGAGATTCGGCGCGTGGT
GCAGGTGCTCAGCCGGCGCACCAAGAACAATCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGACCGCCATCGTCGAGG
GCCTGGCCCAGCGCGTGGTCACGGGCGATGTGCCCGAGTCGTTGCGGGGTAAGACCGTGATCTCACTGGACCTCGGCTCG
ATGGTCGCGGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGGCTCAAGGCCGTGCTCGATGAGATCAAGGCCAGCTCCGG
ACAGATCATCACCTTCATCGATGAGCTGCACACCATCGTCGGCGCCGGTGCCACCGGCGATTCCGCGATGGACGCCGGCA
ACATGATCAAGCCGATGCTGGCCCGCGGTGAGCTGCGCCTCGTGGGCGCCACCACGCTCGATGAGTACCGGCAGTACATC
GAGAAGGACGCCGCGCTCGAACGCCGCTTCCAGCAGGTGCTGGTGGGCGAGCCGAGCGTGGAGGACACCATCGGCATCCT
GCGCGGGCTCAAGGAGCGCTACGAGGTGCACCACGGCGTACGCATCACCGACTCCGCGCTGGTCTCGGCCGCGTCGCTGT
CGGACCGCTACATCACGTCACGGTTCCTGCCCGACAAGGCGATCGACCTCGTCGACGAGGCCGCCTCGCGCCTGCGCATG
GAGATCGACTCCCGCCCGGAGGAGATCGATGCGGAGGAGCGCATCGTGCGCCGCCTCGAGATCGAGGAGATGGCGCTGTC
CAAGGAAACCGATGCGGCCTCCGTCGATCGGCTGGAGAAGCTGCGCGGCGAGCTCGCCGATCACAAGGAGAAGCTGGCCC
AGCTCACCTCCCGCTGGCAGAACGAGAAGGGCGCCATCGATTCGGTGCGCACCCTCAAGGAGCAGTTGGAGAACCTCAAG
GGCGAATCCGATCGCGCCGAGCGCGACGGTGACCTCGGCCGCGCCGCGGAGCTGCGCTACGGCCAGATCCCCGCGCTGGA
GAAGGAACTCGACGAGGCCGTGGCCGCATCGGGTGCCGCCTCCGACGGCGAGGTGATGCTCAAGGAGGAGGTCGGTCCCG
ACGATGTGGCCGATGTGGTCTCCTCCTGGACCGGTATTCCCGCGGGCCGCATGCTCGAAGGTGAGACCGCCAAGCTGTTG
CGCATGGAATCCGAGATCGGTAAGCGCGTGATCGGCCAGGAGGCCGCTGTGGAGGCGGTCTCGGATGCGGTGCGCCGCAC
CCGCGCCGGTGTCGCCGACCCGAACCGGCCCACCGGGTCCTTCCTGTTCCTCGGTCCCACGGGTGTGGGTAAGACGGAGC
TCGCGAAGGGCTTGGCGGAGTTCCTGTTCGACGACGAGCGGGCCATGGTGCGCATCGATATGTCCGAGTACGGCGAGAAG
CACTCCGTCGCTCGGCTGGTCGGCGCGCCTCCCGGCTACGTCGGCTACGAGGCCGGCGGTCAGCTGACCGAGGCGGTGCG
GCGCCGCCCCTACACGGTGGTGCTGTTCGACGAGGTCGAGAAGGCGCACCCGGATGTCTTCGACGTGCTGCTGCAGGTGC
TCGACGAGGGTCGGCTCACCGATGGTCAGGGTCGCACCGTGGACTTCCGCAACACGATCCTGATCCTCACGTCGAACCTC
GGTGCGGGCGGCGACAAGGACCACGTGATGAACGCGGTGCGGGCCAAGTTCAAGCCGGAGTTCATCAACCGGCTCGACGA
TGTGCTCATCTTCGACTCGCTCGACTCCGGACAGCTCACCGGCATCGTCGACATCCAGCTCGATCAGCTGCGCAAGCGGC
TCTCGCAGCGCCGACTCGACCTCCAGGTCTCCGATGAGGCGAAGGGGTGGCTCGCGGAGCGCGGTTTCGACCCGCTCTAC
GGTGCCCGTCCACTGCGCCGCCTGGTGCAGCAGTCGATCGGCGACCAGCTCGCCAAAGCGCTGCTCGCGGGCGACGTCCG
CGACGGTGACCCGGTGAAGGTCACCGTCAGCGAGGACGGCGACCGGTTGATCATCAACTGA

Protein sequence :
MDSFNPTTKTQAALTSALQAASAAGNPEISPAHLLVALLDQTDGIAAPLLKAVGVDPVTVRNRAQELVDRKPKASGSTTQ
PQLSRESLASITAAQKLATEMGDQYVSTEHVLYGLSEAAQVLGNAGATPQAIQEAFTAVRGSAKVTSQDPEGQYQALEKY
STDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRVVTGDVPESLRGKTVISLDLGS
MVAGAKYRGEFEERLKAVLDEIKASSGQIITFIDELHTIVGAGATGDSAMDAGNMIKPMLARGELRLVGATTLDEYRQYI
EKDAALERRFQQVLVGEPSVEDTIGILRGLKERYEVHHGVRITDSALVSAASLSDRYITSRFLPDKAIDLVDEAASRLRM
EIDSRPEEIDAEERIVRRLEIEEMALSKETDAASVDRLEKLRGELADHKEKLAQLTSRWQNEKGAIDSVRTLKEQLENLK
GESDRAERDGDLGRAAELRYGQIPALEKELDEAVAASGAASDGEVMLKEEVGPDDVADVVSSWTGIPAGRMLEGETAKLL
RMESEIGKRVIGQEAAVEAVSDAVRRTRAGVADPNRPTGSFLFLGPTGVGKTELAKGLAEFLFDDERAMVRIDMSEYGEK
HSVARLVGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILILTSNL
GAGGDKDHVMNAVRAKFKPEFINRLDDVLIFDSLDSGQLTGIVDIQLDQLRKRLSQRRLDLQVSDEAKGWLAERGFDPLY
GARPLRRLVQQSIGDQLAKALLAGDVRDGDPVKVTVSEDGDRLIIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-101 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tpau_0494 YP_003645474.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-110 43