Gene Information

Name : Tpau_4058 (Tpau_4058)
Accession : YP_003648967.1
Strain : Tsukamurella paurometabola DSM 20162
Genome accession: NC_014158
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 4189589 - 4191112 bp
Length : 1524 bp
Strand : +
Note : KEGG: rop:ROP_61390 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase

DNA sequence :
ATGACCGTTTACGCACGTCCCGGGGCCCCCGGCTCCCTCATGAGCTACCAGTCCCGGTACGACAACCTGATCGGCGGCCA
GTGGGTGGCGCCGGTGCAGGGCCGGTACTTCGAGAACCCGTCGCCCGTGACCGGGCAGGTGTTCTGCGAGGTGGCCCGGT
CGACCGCCGAGGACATCGAGCTGGCACTCGACGCCGCGCACGCGGCCGCCCCCGGCTGGGGCAAGACGGCGGCCACGGCC
CGCGCGAACATCCTGCTGCAGATCGCCGACCGGATGGAGGCGAACCTGGAGGCGATCGCCGTCGCCGAATCGTGGGAGAA
CGGCAAGCCGGTCCGCGAGACGCTCAACGCCGACATCCCGCTCGCGATCGATCACTTCCGGTACTTCGCGTCGGTGCTGC
GGGCCCAGGAGGGCAGCATCTCCGAGATCGACGAGAACACTGTGGCCTACCACTTCCATGAGCCGCTCGGCGTTGTGGGA
CAGATCATTCCGTGGAACTTCCCGATCCTCATGGCGGTGTGGAAGCTGGCCCCGGCGCTCGCCGCGGGCAACGCGATCGT
GCTCAAGCCCGCCGAGCAGACGCCGGTCTCCGTGCTGTACCTGTTCTCGCTGATCGGCGATCTGCTGCCGCCGGGTGTGG
TGAACATCGTCAACGGTTTCGGCCTGGAGGCGGGTAAGCCGCTGGCGTCGAGCAAGCGGATTCGCAAGATCGCCTTCACC
GGTGAGACCACCACGGGCAAGCTGATCGCCGGTTACGCCGCCGACAACCTGATTCCGGTCACGCTGGAGTTGGGAGGCAA
GAGCCCGAACGTCTTCTTCAAGGACGTCATGGCCGCGAACGACGATTACCAGGACAAGGCGCTCGAGGGCTTCACGATGT
TCGCGCTGAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGCGCGCTGCTGGAGAAGCCGATCTTCGACGAGTTCCTCGAA
CTCGGTTCGATCCGCACCAAGTCGATCATCCAGGGCGATCCGCTCGATACCGACACCATGATCGGCGCACAGGCGTCGAA
GGAGCAGCACGAGAAGATCCTGTCGTACATCGACATCGGGCGCAGCGAGGGTGCCACCCTGGTCACCGGTGGTGAGGCGG
CCGATCTCGGCGGCGACCTGTCGGGCGGCTACTACATCCAGCCGACCATCTTCTCGGGCTCGAACGACATGCGGATCTTC
CAGGAGGAGATCTTCGGCCCCGTGCTCGCGGTGACCTCGTTCGACGGTTACGACAACGCGATGGAGATCGCCAACGACAC
CCGCTACGGCCTCGGCGCCGGCGTATGGTCGCGCAACGGCGACATCGCCTATCGCGCGGGCCGCGATATCCAGGCCGGGC
GCGTGTGGACGAACACCTACCACCAGTACCCTGCGCATGCGGCGTTCGGCGGCTACAAGGATTCGGGTATCGGCCGGGAG
AACCACAAGATGATGCTCGATCATTACCAGCAGACGAAGAACCTGCTGGTCTCGTACGCGCCCACCGCGCAGGGCTTCTT
CTGA

Protein sequence :
MTVYARPGAPGSLMSYQSRYDNLIGGQWVAPVQGRYFENPSPVTGQVFCEVARSTAEDIELALDAAHAAAPGWGKTAATA
RANILLQIADRMEANLEAIAVAESWENGKPVRETLNADIPLAIDHFRYFASVLRAQEGSISEIDENTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAIVLKPAEQTPVSVLYLFSLIGDLLPPGVVNIVNGFGLEAGKPLASSKRIRKIAFT
GETTTGKLIAGYAADNLIPVTLELGGKSPNVFFKDVMAANDDYQDKALEGFTMFALNQGEVCTCPSRALLEKPIFDEFLE
LGSIRTKSIIQGDPLDTDTMIGAQASKEQHEKILSYIDIGRSEGATLVTGGEAADLGGDLSGGYYIQPTIFSGSNDMRIF
QEEIFGPVLAVTSFDGYDNAMEIANDTRYGLGAGVWSRNGDIAYRAGRDIQAGRVWTNTYHQYPAHAAFGGYKDSGIGRE
NHKMMLDHYQQTKNLLVSYAPTAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-139 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-146 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-146 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-146 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-145 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tpau_4058 YP_003648967.1 aldehyde dehydrogenase VFG0082 Protein 7e-140 62