Gene Information

Name : TherJR_0928 (TherJR_0928)
Accession : YP_003639695.1
Strain : Thermincola potens JR
Genome accession: NC_014152
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 939346 - 941952 bp
Length : 2607 bp
Strand : +
Note : TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA; ATPase AAA; Clp domain protein; Clp ATPase-like; KEGG: dae:Dtox_2007 ATP-dependent chaperone ClpB; SMART: ATPase AAA

DNA sequence :
ATGGATTTGCATCGCTACACGCAAAAATCGAGAGAAGCTTTAGCGGGAGCCCAGCAATTGGCGGCTCAAAGGCATCACCA
GGAAGTAACGGGCAAGCACCTGCTGGCTGTCCTGCTTACCCAGGAAGGAGGTATGGCGCCCAGGTTCCTCGAACATGCAG
GAGTAAACGTAGGGGCGCTGGCTGCCGGTGTTGAGGGACTGCTAAAAAAAATACCGGTGGTTACAGGCTATGAAGGTTCT
TTATATGCCGGATCCGGTTTCACCCGCACCCTTGCCCGGGCTGAGCAGGAAGCACGGGATATGAAAGACGATTATGTCAG
TGTTGAACACCTTTTGCTGGCCCTGTTGGAAGACGGTGAACCTGAGCTTAAAGAAGTGCTGCGGCGGAATGGATTAACGA
GGGAAAACCTATTGCATTCTCTGCGCTCCATACGGGGTAATCAGCGAGTGACGGGAGAAAATCCCGAAGAAACCTACGAA
GCCCTGGAAAAATACGGCCGGGATTTGACCAAACTGGCGCGGCAGGGCAAATTGGACCCTGTCATAGGTAGAGATGAAGA
GATCCGCCGGGTTATTGAAATTCTCTCGCGGCGGACGAAAAACAATCCTGTCCTGATAGGGGAACCGGGCGTTGGTAAAA
CGGCCATCGTCGAGGGGCTGGCCCGCCGTATAGTGGCCGGGGACGTACCCGAAGGTTTAAAGGATAAAGTTTTGATTGGC
CTGGATATGGGCGCCCTGATTGCCGGGGCCAAGTACCGAGGAGAATTTGAAGAGCGTTTAAAGGCAGTGCTTAAGGAAGT
ACAGGAATCCAACGGTAAAATCATCTTATTTATAGACGAATTACATACCGTTGTAGGGGCCGGGGCAGCCGAAGGAGCCG
TTGATGCCGGGAACCTCTTAAAACCCATGCTGGCCCGCGGTGAACTGCGGACCATTGGCGCCACTACTCTGGACGAATAC
AGGAAACATGTAGAAAAAGACGCAGCCCTGGAAAGGCGTTTTCAGCCGGTACTGGTCAACCCGCCTTCCGTGGAAGATAC
CATTTCCATTTTGCGGGGCCTTAAGGAGCGCTATGAAGTACACCACGGGGTACGCATCAAAGACAGCGCCATTGTAGCGG
CGGCAGTCCTGTCTGACCGGTATATTTCAGACCGGTTCCTGCCTGACAAAGCCATAGACTTAATGGATGAGGCGGCAGCC
CGGATCAGAACGGAAATCGACAGTTTGCCCACTGAACTGGATGAAATAACCCGCCGTATCATGCAGATGGAAATCGAAGA
AGCGGCTCTGAGCAAGGAAAAAGACGAAGCGTCCCAGGAAAGATTGGAAAAGTTAAGAAGCCAGCTGGCCGAACTGCGCA
GTGAGGCCGATGCCATGAAGGCCCAGTGGGAGGTGGAAAAACAGGCCATCAGCCGGTTGCGGGAGATTAAGAAAGAAATT
GAGGAAACCAGACAGGAAATTGAGCGGGCAGAAAGAGAATACGACCTGAACCGGCTGGCTGAATTAAGATACGGCAAATT
GGCCAACCTGGAACGCCAGTTAAAAGAAGAAGAGGAAACCCTGGCCGGTAAGCAGAAACATGGTATGCTGTTGAAGGAAG
AGGTGGACGAGGAAGATATTGCCCGTGTGGTCAGCCGTTGGACCGGTATACCGGTAAGCAGGCTGATGGCCGGGGAAAAA
GAAAAACTCATTCACCTTGACGAGGAACTGCACAAACGGGTTGTCGGACAGGATGAAGCTGTCCGGGCCGTGGCAGATGC
TGTCTTACGTGCCCGGGCCGGTATTAAGGACCCTAACCGACCGATCGGCAGTTTCATTTTCCTCGGCCCGACGGGAGTGG
GCAAGACGGAATTGGCACGGGCCCTGGCCCAGGCCCTTTTCGATGATGAACGCAACATGATCCGGCTTGATATGTCTGAG
TACATGGAGAAACACACGGTGGCCAGGTTAATCGGCGCCCCGCCCGGTTATGTCGGTTACGAAGAAGGCGGGCAGCTTAC
TGAGGCTGTCCGGCGCAAGCCTTATTCTGTCGTTTTACTTGACGAAATTGAAAAGGCTCATAACGATGTTTTCAACGTGT
TGCTACAATTACTGGACGACGGGCGCCTGACCGACGGCCAGGGGCGGACGGTAAATTTCCAGAACACCGTGGTAATCATG
ACCTCTAACCTGGGCAGCCAGGAGATTCTCGCGCAACGGGAGCGTGGCGGCGATTACGAACAGATGAAGGAAAGTGTGCT
GGGTATATTGCGACAGTACTTCCGCCCCGAATTCCTGAACCGGGTTGATGAAATCGTTGTCTTCCATGCTTTAAAACAGG
AGCAGGTGAAAGAGATTGCCCGCCTGCTGATGGAAAAGTTAGCGGCGCGTGTCTATGCAGGCGCCGGCGTTAAACTGGAA
TGGACGGAAAATGCCCTTACTTACCTGGCAGATAAGGGTTATGAACCTTCTTACGGAGCCAGGCCGTTAAAACGCCTAAT
TCAGCAGGAAGTGGAAACGCCATTGAGCCGTATGCTGGTAAAAGGGGAAATTTCTGATAAAGAGACCGTTGTCCTGCAGG
CCGAAAACGGCGTTTTGACCTTTACCAAAAAAACTGAATCGAAGTAA

Protein sequence :
MDLHRYTQKSREALAGAQQLAAQRHHQEVTGKHLLAVLLTQEGGMAPRFLEHAGVNVGALAAGVEGLLKKIPVVTGYEGS
LYAGSGFTRTLARAEQEARDMKDDYVSVEHLLLALLEDGEPELKEVLRRNGLTRENLLHSLRSIRGNQRVTGENPEETYE
ALEKYGRDLTKLARQGKLDPVIGRDEEIRRVIEILSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPEGLKDKVLIG
LDMGALIAGAKYRGEFEERLKAVLKEVQESNGKIILFIDELHTVVGAGAAEGAVDAGNLLKPMLARGELRTIGATTLDEY
RKHVEKDAALERRFQPVLVNPPSVEDTISILRGLKERYEVHHGVRIKDSAIVAAAVLSDRYISDRFLPDKAIDLMDEAAA
RIRTEIDSLPTELDEITRRIMQMEIEEAALSKEKDEASQERLEKLRSQLAELRSEADAMKAQWEVEKQAISRLREIKKEI
EETRQEIERAEREYDLNRLAELRYGKLANLERQLKEEEETLAGKQKHGMLLKEEVDEEDIARVVSRWTGIPVSRLMAGEK
EKLIHLDEELHKRVVGQDEAVRAVADAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELARALAQALFDDERNMIRLDMSE
YMEKHTVARLIGAPPGYVGYEEGGQLTEAVRRKPYSVVLLDEIEKAHNDVFNVLLQLLDDGRLTDGQGRTVNFQNTVVIM
TSNLGSQEILAQRERGGDYEQMKESVLGILRQYFRPEFLNRVDEIVVFHALKQEQVKEIARLLMEKLAARVYAGAGVKLE
WTENALTYLADKGYEPSYGARPLKRLIQQEVETPLSRMLVKGEISDKETVVLQAENGVLTFTKKTESK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 7e-163 49
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-99 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-99 43
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-102 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TherJR_0928 YP_003639695.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-118 45
TherJR_0928 YP_003639695.1 ATP-dependent chaperone ClpB VFG2084 Protein 4e-105 44