Gene Information

Name : TherJR_0899 (TherJR_0899)
Accession : YP_003639667.1
Strain : Thermincola potens JR
Genome accession: NC_014152
Putative virulence/resistance : Unknown
Product : adenine-specific DNA-methyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 909801 - 911357 bp
Length : 1557 bp
Strand : +
Note : KEGG: dol:Dole_2236 N-6 DNA methylase; PFAM: N-6 DNA methylase

DNA sequence :
ATGCCGTCGATCAACAATGAAATAGAGAAAAAGCTCTGGAATGCCGCCGACCAACTGAGGGCCAATTCCAAGCTCAAAGC
TTCCGAGTATTCGGTGCCCGTCCTCGGGCTTATCTTCCTCAGATTTGCCGACCAAAGATTCAGTGCGGCTGAAAAGGAGC
TTGTCGAGAAAGCAAAGGTATCAGGTTCCAGGCGCGCCATCGGCAAGGCCGATTACCAGGCCAGAGGGGTCATGTACTTG
CCGGAACAGGCAAAGTATTCTTATCTTCTAAAGCTGCCGGAAGGGGAGAATATCGGCAAGGCCGTCAACGAGGCCATGAA
AGCCATCGAAGCCGAAAACGAAGACCTGAAGGATGTCCTTCCCAAAACCTATACACGCCTAGACAATGATACACTGATTG
CGCTGCTTAAAATATTCTCTGAAATCCCCATGGATGTGGAAGGGGATGTCTTCGGCAATGTATATGAATACTTTCTCGGC
GAGTTTGCCCGTTCGGAAGGGCAGCGCGGCGGCGAGTTCTATACGCCTACCTCGCTGGTTAAGCTTATCGTCGAGGTGAT
CGAGCCGTACAAGGGCCGTATCCTGGACCCAGCCTGCGGGTCGGGCGGCATGTTTGTCCAGTCCGCCCGGTTTGTCCAGA
ACCACAAGAAAAACCCCAGCAGCGAGATATCCATCTACGGCCAGGAGAAGGTAGCCGAAACGGTCCGGCTCTGCAAAATG
AACCTGGCGGTGCACGGCCTCTCAGGCGACATCCGGCAGGCCAACACCTACTACGAAAATGTGCATAACTGCATAAACCG
CTTTGACTTTGTCATGGCCAATCCGCCCTTCAATGTGGACGGTGTGGACAAGGAAAAGATCAAGGATGATCCACGGTATC
CCTTCGGGTTGCCTTCCAACGATAACGCCAATTACATATGGATTCAGGAGTTTTACAGTGCTTTAAATGATAAGGGTCGG
GCCGGTTTTGTCATGGCCAACTCCGCCAGCGACGCCAGGGGCTCGGAACTGGAAATAAGAAAAAAGCTCATCCAGGACAA
GGTTGTCGATGTGATGATCGCCATCGGTCCAAACTTCTTTTACACCGTTACCCTGCCCTGCACCCTCTGGTTCTTTGACA
AGGGCAAACGCCAGACTGAACGGGGAGATAAAGTACTGTTCATCGACGCGCGGAACATCTACCGCCAGGTGGACCGGGCC
CATCGGGAGTTTACGCCGGAGCAGATTGAATTTATCGCCAACATAGTGCGGTTGTACCGAGGCGAGCCGGTGGAAACCGC
GAGCGGCAGTGAGGATATGCTCAAGGAACATTTTCCTGAAGGTAAATATGTAGATATTCCCGGCCTGTGCAAGGTAACAA
CCATCGCGGAAATCGAGGCCCAGGGCTGGAGCCTCAACCCCGGGAGGTATGTGGGGGTAGCCCAGAAGGACGAGGAAGAC
TTCGACTTTATGGAAAGGCTGCAGGAACTGAATGAGGAATTGGAGCGGCTTAACGCCGAGGCAGCGGAGCTGGAGGAGAG
GATAAGAGAGAATGTGGATCGGATATTGAGTGTTTGA

Protein sequence :
MPSINNEIEKKLWNAADQLRANSKLKASEYSVPVLGLIFLRFADQRFSAAEKELVEKAKVSGSRRAIGKADYQARGVMYL
PEQAKYSYLLKLPEGENIGKAVNEAMKAIEAENEDLKDVLPKTYTRLDNDTLIALLKIFSEIPMDVEGDVFGNVYEYFLG
EFARSEGQRGGEFYTPTSLVKLIVEVIEPYKGRILDPACGSGGMFVQSARFVQNHKKNPSSEISIYGQEKVAETVRLCKM
NLAVHGLSGDIRQANTYYENVHNCINRFDFVMANPPFNVDGVDKEKIKDDPRYPFGLPSNDNANYIWIQEFYSALNDKGR
AGFVMANSASDARGSELEIRKKLIQDKVVDVMIAIGPNFFYTVTLPCTLWFFDKGKRQTERGDKVLFIDARNIYRQVDRA
HREFTPEQIEFIANIVRLYRGEPVETASGSEDMLKEHFPEGKYVDIPGLCKVTTIAEIEAQGWSLNPGRYVGVAQKDEED
FDFMERLQELNEELERLNAEAAELEERIRENVDRILSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 2e-86 42
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 9e-86 41
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 4e-87 41