Gene Information

Name : TherJR_0607 (TherJR_0607)
Accession : YP_003639381.1
Strain : Thermincola potens JR
Genome accession: NC_014152
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 603108 - 604826 bp
Length : 1719 bp
Strand : +
Note : KEGG: pjd:Pjdr2_4326 urease, alpha subunit; TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
ATGAGTTTGAAAATGACGCGCCGGGAGTATGCCGATATGTTTGGACCTACGGTGGGAGACAGGGTGCGCCTGGCCGATAC
TGATATTATCATTGAAGTTGAACGCGATTTTACGGTTTACGGAGACGAGTGCAAATTCGGCGGGGGTAAGGTACTGCGGG
ACGGGATGGGTCAGTCCCCGAACGCTACCAGGGAAGAGGGGGTTTTGGACCTGGTCATCACTAATGCACTGATCCTCGAC
CACTGGGGTATTGTTAAGGCCGATATCGGTATCCGTGACGGAAGAATTGTCGGTATAGGCAAGGCTGGGAACCCTAACCT
GATGGACGGGGTTGACCCCGGTATGGTTGTGGGGGCTGCTACGGAAGTTATTGCCGGGGAAGGGATGATTGTAACACCCG
GTGGGATAGATACCCACATTCACTTTATTTCCCCGCAGCAGGTAGAAACGGCCATTGCCTCCGGAATCACAACCATGATT
GGCGGGGGCACAGGTCCGGCAACAGGGACCAATGCCACTACCTGCACCCCGGGAGCCTGGAATATTCATAAGATGCTGGA
AGCCGCGGAAGAGTTTCCGGTGAACATGGGTTTTCTGGGCAAAGGCAACTGTTCTTTTGCAGCCCCTTTGATCGAACAGG
TTATGTCCGGGGCTATGGGCTTAAAACTTCATGAAGACTGGGGGTCCACACCTGCAGCCATTGACAAGTGCCTGCGTGTT
GCCGATGAATACGATGTACAGGTAGCCATTCATACCGACACCCTGAACGAAGCCGGGTTTGTGGAAGATACAATTGCCGC
TATCAACGGGCGGACCATTCACACTTACCATACTGAAGGCGCGGGTGGCGGCCACGCCCCCGATATCATCAGGATTGCCG
CCGAACCCAACGTGTTGCCTTCATCCACAAACCCTACGCGCCCTTTTACAATTAACACTGTCGACGAGCACCTGGATATG
CTGATGGTCTGCCATCACCTGGACAGCAAAGTACCTGAGGATGTTGCCTTTGCAGATTCACGGATAAGGGCCGAAACCAT
TGCCGCCGAAGACATTCTTCATGACCTGGGTGTTTTCAGTATGTTCAGCTCTGATTCTCAGGCTATGGGCCGGGTAGGTG
AGGTTATTATCCGGACCTGGCAGACAGCGGACAAGATGAAAAAACAGCGCGGGCCTTTACCTGAAGATAGCAGCAGGAAT
GATAATTTCCGGGCCAAGCGCTATATTGCCAAATACACCATCAATCCGGCCGTTACTCACGGGATCAGCAGGTATGTGGG
TTCTATTGAAACCGGGAAACTGGCTGACATTGTCCTGTGGCAGCCCAGGTTTTTCGGCGTAAAGCCGGAAATAGTGATCA
AGGGTGGTATGATAGCCTACAGCCAGATGGGCGATGCCAACGCCTCTATCCCTACGCCGCAGCCCGTCTTTTCCAGGCCT
ATGTTCGGTGCCCTGGGCAAAGCAAAGTTCCGGACCTGTTTGACCTTTGTATCGGAATACGCTTTTGTCCATGGTATTAA
ATCTCTGCTGGGCTTGGAAAAAGAGGTTGTGCCGGTGAAGAACTGCCGGAGCATATCTAAAAAGCAGATGCTCCACAACG
ATGCGCTGCCGGATATTACCGTTGACCCGGAAACCTATGAAGTAAGGGTCAACGGGGAGCTTTTAACCTGCGAGCCGGCG
AAGGAACTGCCGCTTGCCCAGAGATACTTTCTGTTTTAA

Protein sequence :
MSLKMTRREYADMFGPTVGDRVRLADTDIIIEVERDFTVYGDECKFGGGKVLRDGMGQSPNATREEGVLDLVITNALILD
HWGIVKADIGIRDGRIVGIGKAGNPNLMDGVDPGMVVGAATEVIAGEGMIVTPGGIDTHIHFISPQQVETAIASGITTMI
GGGTGPATGTNATTCTPGAWNIHKMLEAAEEFPVNMGFLGKGNCSFAAPLIEQVMSGAMGLKLHEDWGSTPAAIDKCLRV
ADEYDVQVAIHTDTLNEAGFVEDTIAAINGRTIHTYHTEGAGGGHAPDIIRIAAEPNVLPSSTNPTRPFTINTVDEHLDM
LMVCHHLDSKVPEDVAFADSRIRAETIAAEDILHDLGVFSMFSSDSQAMGRVGEVIIRTWQTADKMKKQRGPLPEDSSRN
DNFRAKRYIAKYTINPAVTHGISRYVGSIETGKLADIVLWQPRFFGVKPEIVIKGGMIAYSQMGDANASIPTPQPVFSRP
MFGALGKAKFRTCLTFVSEYAFVHGIKSLLGLEKEVVPVKNCRSISKKQMLHNDALPDITVDPETYEVRVNGELLTCEPA
KELPLAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-167 68
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-167 68
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-158 64
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-157 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-158 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 8e-158 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TherJR_0607 YP_003639381.1 urease subunit alpha VFG0270 Protein 2e-165 68