Gene Information

Name : TherJR_2325 (TherJR_2325)
Accession : YP_003641067.1
Strain : Thermincola potens JR
Genome accession: NC_014152
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2399644 - 2401395 bp
Length : 1752 bp
Strand : -
Note : KEGG: pth:PTH_2214 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region

DNA sequence :
GTGAGGAAAACTAAAATAGTTTGTACTATCGGCCCAGCCAGTGAATCTGTGGAGAAACTTGTCCAGCTGATAGAAAAAGG
CATGAATGTGGCCCGGCTGAATTTCTCCCACGGTACCCATGCAGAGCATCTGGCGAGGGTAAAAAACATAAGGGAAGCAG
CGGCCAAAACAGGGACTGTTGTTGCGATTATGCTTGATACCAAGGGGCCTGAGATCCGGACCGGTGTTTTGAAGACAGAA
AAGATACGCCTGGTTAACGGCCGTAAGATAAAACTAACCCCTAAAGAAGTGGAAGGAACAGAGGAACTCCTGTCTTTAAG
CTATCCTGATTTAACAAAGGATGTGGCACCCGGCGACCGGATCCTGATAGCTGACGGCCTGGTGGAATTGCGAGTGGAAA
AAGTAGTAGATGATTATGTAGAATGCCTGATTGTAAACGGAGGCGAAATTGGCAGCCGGAAAAATGTGAACATCCCGGGG
GTGAAGGTTAAACTGCCTTCCATTACGGAAAAAGATGTGGAAGACATCAACTTTGCCGTGGAACACGGTTTCGACTTTAT
CGCTGCATCTTTTGTGCGGACGGCAGGTGACGTGCTGGCCATCAGGAGGATCCTGGAAGAGAAGGATGCCGACATATCCA
TTATTGCTAAAATTGAAAGCCGCCAGGGCATGGAGAACATAGACGAAATACTGAAAGTGGCCGACGGCATAATGGTGGCG
CGGGGCGACCTGGGGGTAGAGATCCCCACCGAAGAAGTCCCCCTGGTGCAGAAGATGATTATAGAAAAATGTAACCGGGC
CGGCAAACCGGTTATTACTGCCACTCAGATGCTTGAATCCATGGTGCATAACCCCCGGCCTACCAGGGCTGAAGCTACGG
ATATCGCCAACGCCATTTTTGACGGGACCGATGCCATCATGCTGTCGGGCGAAACGGCGGCAGGCGAGTTCCCGGTGGAG
GCCGTGGAAATAATGGCCAGGATAGCCCAACGTACAGAAGTCGCGCTGCGGTACAAAGAGCTTTCAATAAAACGGGAAGC
ATCCCCGCTGCGCACTGTTACCGATGCCATCAGCCACGCCACCTGTACTACGGCTTTTGACTTAGGAGCTGCGGCCATCA
TAACTTCCACCAAATCAGGGTACACAGCCCGGATGGTTTCCAAATACCGGCCCCATGCTCCGATCATTGCTGTGACGCCA
AAGATGAGCGTGGTGCGCAAGTTGAACCTGGTCTGGGGCGTGTATCCATTACTGGTCGCGGAAACGACAGGTACTGACGA
AATGATCGCCGAGGCTATCCAAACATCGCTGGCAGCCAATTTGATTAAATGCGGCGACCTGGTAGTCATCACCGCCGGTG
TGCCGGTGGGGGTTCCGGGGACAACCAACCTGCTCAAGGTGCATATCGTGGGCGATGTGGTGCTCAGGGGAGCCGGTATC
GGCGCCCGGGCCGTAACGGGGAAAGTGAAAATAGTGAAAAACGCCAGAGAAGCCCTGCAACGCATTGAGCCGGGTGACAT
TATGGTTACTAACAGTACAGAAAAGGAATTTGTACCGGCTATCGAAAAATGTGCCGCCATAATAACGGAAGTAGGAGGTC
TGACCTCTCACGCCGCCATAGTGGGCCTGAACCTGGGTATCCCGGTGGTGGTGGGGGCCGACGGCGCTACATCTATTCTG
GAGGACGGCCAAACCGTCACTGTGGACGGTATGCGCGGTTTAGTTTACCGTGGCGCTGCCCGGGTTCTTTAA

Protein sequence :
MRKTKIVCTIGPASESVEKLVQLIEKGMNVARLNFSHGTHAEHLARVKNIREAAAKTGTVVAIMLDTKGPEIRTGVLKTE
KIRLVNGRKIKLTPKEVEGTEELLSLSYPDLTKDVAPGDRILIADGLVELRVEKVVDDYVECLIVNGGEIGSRKNVNIPG
VKVKLPSITEKDVEDINFAVEHGFDFIAASFVRTAGDVLAIRRILEEKDADISIIAKIESRQGMENIDEILKVADGIMVA
RGDLGVEIPTEEVPLVQKMIIEKCNRAGKPVITATQMLESMVHNPRPTRAEATDIANAIFDGTDAIMLSGETAAGEFPVE
AVEIMARIAQRTEVALRYKELSIKREASPLRTVTDAISHATCTTAFDLGAAAIITSTKSGYTARMVSKYRPHAPIIAVTP
KMSVVRKLNLVWGVYPLLVAETTGTDEMIAEAIQTSLAANLIKCGDLVVITAGVPVGVPGTTNLLKVHIVGDVVLRGAGI
GARAVTGKVKIVKNAREALQRIEPGDIMVTNSTEKEFVPAIEKCAAIITEVGGLTSHAAIVGLNLGIPVVVGADGATSIL
EDGQTVTVDGMRGLVYRGAARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-98 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-98 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-98 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-97 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TherJR_2325 YP_003641067.1 pyruvate kinase VFG0479 Protein 2e-98 49