Gene Information

Name : TherJR_2114 (TherJR_2114)
Accession : YP_003640860.1
Strain : Thermincola potens JR
Genome accession: NC_014152
Putative virulence/resistance : Unknown
Product : Homoserine dehydrogenase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0460
EC number : 1.1.1.3
Position : 2184965 - 2186278 bp
Length : 1314 bp
Strand : -
Note : KEGG: pth:PTH_1601 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein

DNA sequence :
ATGGAGAGAGAAATAAAAGTAGGGTTGCTGGGCTGTGGTACAGTAGGTGGCGGCGTATGGAAGGTTTTGGCTAAGAACAG
GGATAACATTCAGAAAAAAGTAGGAGCAGATATTACCGTTAAACGTGTTTTGGAAAGGGATAAGGAAAAGGCTGTGGCAG
CCGGTGTTCCGGCTGAGATCATAACTACTGACATAAACGATATTATTGATGACCCTGAAATTAAAATAGTTGTTGAGGTA
GTCGGCGGCATTGAGGTTGCCGGAGAATTCATACATAAAGCTTTAAAAGCGGGAAAAAGTGTGGTAACCGCAAATAAGGA
CCTACTGGCTGTTCAGGGGCGGGAACTCTATGAACTGGCTGAGGCCAATAACTGTGACCTGCTTTTTGAAGCCAGCGTTG
GCGGTGGCATACCAATCATCAGACCGCTAAAAGAATGCCTTGCCGGGAATAAAATTGAAGCAATTTACGGAATTGTAAAC
GGAACCACGAATTATATGCTTACAAAAATGACCAACGAGGGTTCCAGTTATAAAGAGGTCTTGGCAGAAGCCCAGGCCAA
AGGATATGCAGAAGCAGACCCCACTTCTGATGTGGAAGGACTGGATGCCGCCAGAAAATTAGCCATTCTTGCCTCAATTG
CGTTTAATGCCAGGGTATCTTTTGACGATGTTTATGTTGAGGGCATTAGTAAGATTACTGCCCGGGATATAGAATATGCC
AAAGAATTGAATTTTGTGGTCAAGTTATTGGCTATAGGGAAAGAAACTGATGGAAAAATTGAAGTCAGGGTACATCCCAC
AATGATTCCGGTTAACCATCCCCTAGCGTCTGTCAATGACGTATTCAACGCAATTTTTGTCAAAGGGGACGCTTTGGGCG
AAGCTATGTTTTATGGGCGGGGAGCCGGTGAACTGCCCACGGCCAGTGCAGTGGTTGGAGATATTATTGATGCAGCCCGC
AACATAATTAAAGGTGTTCCGGGCAGAATAGGCTGTACCTGTTTCGACCGGGCCGGTTGTAGTTGTTTTGAGAAAAAGCA
AATTAAAGATATGGGCGAGACGCAGGCCAAATATTATATACGGCTCAAAGTTTTAGACCGTCCAGGGGTTTTGGCCGCTA
TTGCCAGTGTATTCGGTAACCAAGAAGTTAGTGTGGCTTCCGTTATTCAGAAACGCAATATAGGGAAAATTGCTGAAATA
GTCTGGGTAACGCATGAAGTTATGGAAAAAAACATTCAGGATGCCTTGAAAATAATTGCAGGGTTATCTATAGTAGAAGA
AGTAAGCAATGTAATTAGAGTAGAAGGAGAATAA

Protein sequence :
MEREIKVGLLGCGTVGGGVWKVLAKNRDNIQKKVGADITVKRVLERDKEKAVAAGVPAEIITTDINDIIDDPEIKIVVEV
VGGIEVAGEFIHKALKAGKSVVTANKDLLAVQGRELYELAEANNCDLLFEASVGGGIPIIRPLKECLAGNKIEAIYGIVN
GTTNYMLTKMTNEGSSYKEVLAEAQAKGYAEADPTSDVEGLDAARKLAILASIAFNARVSFDDVYVEGISKITARDIEYA
KELNFVVKLLAIGKETDGKIEVRVHPTMIPVNHPLASVNDVFNAIFVKGDALGEAMFYGRGAGELPTASAVVGDIIDAAR
NIIKGVPGRIGCTCFDRAGCSCFEKKQIKDMGETQAKYYIRLKVLDRPGVLAAIASVFGNQEVSVASVIQKRNIGKIAEI
VWVTHEVMEKNIQDALKIIAGLSIVEEVSNVIRVEGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00305 YP_008207770.1 Homoserine dehydrogenase Not tested AbaR25 Protein 4e-63 46
BJAB0868_00309 YP_008211635.1 Homoserine dehydrogenase Not tested AbaR26 Protein 4e-63 46