Gene Information

Name : Cfla_0937 (Cfla_0937)
Accession : YP_003636044.1
Strain : Cellulomonas flavigena DSM 20109
Genome accession: NC_014151
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1024619 - 1025854 bp
Length : 1236 bp
Strand : +
Note : KEGG: cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein

DNA sequence : 
GTGACCCACGACCCGCTCGCGCAGCCTCACGACTGGACCGACTCCGGCTTCTCGACCCGCGCCATCCATGCAGGTCAGGA
CCCCGATCCCCGCACCGGGGCCGTCGTCCCGCCCATCTTCCAGGTCTCGACGTACAAGCAGGACGGCGTCGGCGGGCTGC
GGGACGGCTACGAGTACTCCCGTTCCGGCAACCCCACGCGCGACGCGCTGCAGCAGGCGCTGGCCGCCGTCGAGGGCGGC
GACGCCGCGTTCGCGTTCGCGTCGGGCCTTGCGGCGGAGGACACGCTGCTGCGCGCCGTGCTGCGTCCCGGCGACCACGC
GATCGTCCCGAACGACGCCTACGGCGGCACGTACCGCCTCGTCGCACGGGTCCTGGGCCCGTGGGGGATCGAGCACACGC
CCGTCGACCTGTCGGACCCCGACGCGGTGCTCGCGGCGATCCAGCCGGGTCGCACCAAGGTGATCTGGGTCGAGACGCCG
ACGAACCCGCTGCTCGGCATCGCCGACATCGCGGCGATCGCGACGCACGCGCAGGCCGCAGGCATCGTGCTCGCCGTCGA
CAACACGTTCGCCACGCCGTACCTGCAGCAGCCGCTCGCGCTCGGGGCCGACGTGGTCGTGCACTCCACCACCAAGTACA
TCGGCGGGCACTCCGACGTGGTCGGCGGGGCCGTGGTCGTGGCCGACGGCGCGCAGCTCCCGGCCGGCACCGAGGGGCCC
ACGGGCACCACGTCCCTGCGTGACGCGGTCGGGTTCCTGCAGAACGCGTCCGGCGCGGTCGCCGGCCCGTTCGACGCGTG
GCTCACGCTACGCGGGCTGCGCACGCTCGCGGTGCGCATGGACCGGCACGTCGCCAACGCCGAGGCCGTCGCGCGGTTCC
TCGTCGAGCACCCCGGCGTGAACGAGGTGCTGTGGCCCGGGCTGCCCGAGCACCCGGGCCACGAGGTCGCGGCGCGGCAG
ATGACGGGCTTCGGCGGCATGGTCGCGTTCCGCACGGGCTCCGCGGAGTCCGCCGTCGCGGTCTGCGCGGCGACGCGTGT
GTTCACGCTGGCGGAGTCGCTCGGCGGCGTCGAGTCGCTCATCGAGCACCCGGGGCGCATGACGCACGGCTCCGTCGCCG
GCACCGCGCTCGAGGTCCCCGACGACCTGGTCCGCCTGTCGGTGGGCATCGAGGACTCCGCCGACCAGCTCGCCGACCTC
GAGCAGGCGCTGACGGCCGCGGGTATCCACCGGTGA

Protein sequence : 
MTHDPLAQPHDWTDSGFSTRAIHAGQDPDPRTGAVVPPIFQVSTYKQDGVGGLRDGYEYSRSGNPTRDALQQALAAVEGG
DAAFAFASGLAAEDTLLRAVLRPGDHAIVPNDAYGGTYRLVARVLGPWGIEHTPVDLSDPDAVLAAIQPGRTKVIWVETP
TNPLLGIADIAAIATHAQAAGIVLAVDNTFATPYLQQPLALGADVVVHSTTKYIGGHSDVVGGAVVVADGAQLPAGTEGP
TGTTSLRDAVGFLQNASGAVAGPFDAWLTLRGLRTLAVRMDRHVANAEAVARFLVEHPGVNEVLWPGLPEHPGHEVAARQ
MTGFGGMVAFRTGSAESAVAVCAATRVFTLAESLGGVESLIEHPGRMTHGSVAGTALEVPDDLVRLSVGIEDSADQLADL
EQALTAAGIHR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-63 44
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-62 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cfla_0937 YP_003636044.1 cystathionine gamma-synthase BAC0207 Protein 3e-51 42