Gene Information

Name : Cfla_0697 (Cfla_0697)
Accession : YP_003635808.1
Strain : Cellulomonas flavigena DSM 20109
Genome accession: NC_014151
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 753371 - 755074 bp
Length : 1704 bp
Strand : -
Note : TIGRFAM: urease, alpha subunit; KEGG: nml:Namu_0270 urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
GTGGTCGAGATCTCCCGTGCCCGCTACGCGGCGCTGTACGGCCCGACGACGGGTGACCAGGTGCGCCTCGGTGACACCGA
CCTGTGGATCGAGGTCGAGGACGACCTCACGGTCGGCGGCGAGGAGGCCGTGTTCGGCGGCGGCAAGTCGATCCGGGAGT
CCATGGCGCAGGGGTCGACGACGCGCGCGCAGGGCGCCCCCGACACCGTGATCACGAACGCGCTGGTGCTCGACTGGTGG
GGCGTGGTCAAGGCCGACGTCGGCATCCGCGACGGCCGGATCGTCGCGCTCGGCCGCGCCGGCAACCCGGACGTCGCCGA
CGGCGTGCACCCCGACCTGCGCATCGGCCCGTCGACCGACGTCATCAGCGGCGAGGGGCGCGTCCTGACGGCGGGCGGCA
TCGACGTGCACGTGCACTTCCTGTCGCCGTCGCAGGTGCACGAGGCGCTCGCGACGGGCCTGACGACGCTCGCGGGTGGC
GGGACGGGCCCGTCGGAGGGCTCGAAGGCGACCACCGTGACGCCGGGCGCGTGGCACCTGCGCGCGCTGCACCGCGCCCT
GGACACCGCGCCCGTCAACCTGCTCCTGCTCGGCAAGGGCAACACCGTCAGCGCGCAGGGCCTGGCCGAGCAGGCCCTGG
CCGGCGCCGGCGGCTACAAGGTCCACGAGGACTGGGGGTCCACGCCCGCCGCGATCGACGCCGCGCTGCGGGCCGCCGAC
GACTGGGGCCTGCAGGTCGCGCTGCACTCGGACTCGCTCAACGAGGCCGGGTTCGTCGAGTCGACGATCGGCGCGATCGC
CGGCCGGTCCATCCACGCGTTCCACGCCGAGGGCGCCGGCGGCGGGCACGCGCCCGACATCCTCACGGTCGCGTCGCTCC
CCCACGTCATCCCGGGCTCGACCAACCCGACGCTCCCCCACACCGTCAACACCGTGGCCGAGCACCTCGACATGCTCATG
GTCTGCCACCACCTCAACCCCGCCGTGCCGGAGGACCTCGCGTTCGCCGAGTCCCGCATCCGCGCCACGACGATCGCGGC
GGAGGACGTGCTGCACGACATGGGCGCGCTGTCGATCACGTCGTCCGACGCGCAGGCCATGGGCCGCATCGGTGAGGTCA
TCACGCGCACGTGGCAGGTCGCGCACGTCATGAAGCACCGGCGCGGCCCACTGTCGTCCGCGCTGCCCGCCGACAACGAG
CGCGCCCGCCGCTACGTGGCCAAGTACACGATCAACCCGGCCGTCGCGCACGGCATCGACCACGTCGTCGGGTCGGTCGA
GGTCGGCAAGCTGGCGGACCTCGTGCTGTGGGACCCCCGGTTCTTCGGCGTCCGGCCGGACGTGGTCGTCAAGGGCGGCG
CCATCGCGTGGGCCGCGCTCGGCGACCCGAACGCGTCGATCCCGACGCCGCAGCCGGTGCTCATGCGTCCGTCGTTCGCG
GACGCGACGGGCGCAGACGTGTCGGTGTCGTTCGTCGCGCCGGCCGCGCTCGACGACGGCCTCGCCGACCGCCTCGGCCT
GCGCCGCCAACTCGTCGGCATCCGCCCGACGCGTGACGTCGGCAAGGCGCAGATGGTCAACAACGACGCCCTGCCCTGCA
TCGAGGTCGACCCGGAGACGTTCACCATCCGCGTCGACGGCGACGTGATCGAGCCGGCCCCGGCGGAGCACCTCCCCCTC
ACCCAGCTCTACTCCCTCTTCTGA

Protein sequence :
MVEISRARYAALYGPTTGDQVRLGDTDLWIEVEDDLTVGGEEAVFGGGKSIRESMAQGSTTRAQGAPDTVITNALVLDWW
GVVKADVGIRDGRIVALGRAGNPDVADGVHPDLRIGPSTDVISGEGRVLTAGGIDVHVHFLSPSQVHEALATGLTTLAGG
GTGPSEGSKATTVTPGAWHLRALHRALDTAPVNLLLLGKGNTVSAQGLAEQALAGAGGYKVHEDWGSTPAAIDAALRAAD
DWGLQVALHSDSLNEAGFVESTIGAIAGRSIHAFHAEGAGGGHAPDILTVASLPHVIPGSTNPTLPHTVNTVAEHLDMLM
VCHHLNPAVPEDLAFAESRIRATTIAAEDVLHDMGALSITSSDAQAMGRIGEVITRTWQVAHVMKHRRGPLSSALPADNE
RARRYVAKYTINPAVAHGIDHVVGSVEVGKLADLVLWDPRFFGVRPDVVVKGGAIAWAALGDPNASIPTPQPVLMRPSFA
DATGADVSVSFVAPAALDDGLADRLGLRRQLVGIRPTRDVGKAQMVNNDALPCIEVDPETFTIRVDGDVIEPAPAEHLPL
TQLYSLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-137 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-137 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-128 56
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-129 56
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-129 56
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-129 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cfla_0697 YP_003635808.1 urease subunit alpha VFG0270 Protein 2e-124 56