Gene Information

Name : Cfla_3663 (Cfla_3663)
Accession : YP_003638733.1
Strain : Cellulomonas flavigena DSM 20109
Genome accession: NC_014151
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 4047764 - 4049140 bp
Length : 1377 bp
Strand : +
Note : KEGG: ace:Acel_0690 mercuric reductase; TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region

DNA sequence :
ATGGACGAGAACACCTGGGACCTGGTCGTGGTCGGCACCGGGGCAGCGGCGATGGCCGCCGGTATCGAAGCCCGCTCGCG
CGGCAAGCGCGTCCTGCTCGTCGAGCACGGCCCGCTCGGCGGGACGTGCCTGAACATCGGGTGCATCCCGAGCAAGAACC
TGCTCGCCGCCGCCGGGCAGCGCCACCGCGCCCTGGCCAACCCCTTCCCGATGGTCCCCACCACCGCCGGCGAGGTCGAC
GTGCCCGCGCTGATGGGGCGCAAGCAGGACCTGATCGACGGGCTGCGGCAAGCCAAGTACGAGGACGTCGCCGCCGCGCA
CGGCTTCCCGATCCGGCACGGGCACGCACGGTTCGTCGACGAGGCGACGCTGCACGTCGAGGACGAGCCGGTCCGGGCGG
CGGCCTACGTCATCGCCACGGGCGCCGCGCCGCACCTGCCGGACCTGCCCGGACTGCACGACGTCGCCTACCTCACCTCG
ACCACCGCGATGGAGCAGCAGCAGCTGCCCGCGTCGATGGTCGTCATCGGCGGCGGCTACGTCGGGCTCGAGCAGGCGCA
GCTGTGGTCCCACCTCGGAGTGCACGTGACCCTGATCGGCCGAGTCGCACCGCACACCGAACCCGAGGTCGCCGACGTGC
TGCGCGCCGCGTTCCTCACCGACGGCATCCAGCTCCTCGAGGAGCACGCCGTCGCCGTCGAGCGCGGGGCCGACGACACA
GTCCTCGTGCACACCGCCAGCGGCCGAACGGCGAACGGCGAACGGCTGCTGGTCGCGACCGGCCGGGCGGCCGACACCAC
CGGCCTCGGCCTCGACGACGCCGGCGTCGCGACGGACGCCCGCGGCTTCATCGTCGTCGACACCCACCAGCGCACCACCA
ACCCGCGCATCTACGCCGCCGGCGACGTCACCGGAGCACCTCAGTACGTCTACGTCGCCGCGCGGACCGGACACGCGGCG
GCCGCTGGCGCCCTCGGCGACCCCACCGCGGTCGACTACCGCGGCCTTCCCGGCGTCGTCTTCACCACCCCGCAGCTCGC
CTCGGCCGGACTCACTGAACAGCGCGCCCTCGAACTCGGGCACACCTGCGACTGCCGGGTCCTCACAGCTCAGGACATCC
CCCGCGCCCTGGTCAACCAAGACCCACGAGGCGTCCTGAAGCTCGTCACCGACGCCCACACCCGCCAGATCCTCGGCGTC
CACGCCGCACTCGACGGCGCCGGGGAACTCATGCTCGCCGCCACCTACGCCATCAAGTTCGGCCTCACCATCGACGACAT
CGCCGACACCTGGGCGCCCTACCTCACGATGAGCGAAGCGCTGCGCCTTGCCGCCGGACTCTTCCGCACCAACATCCCAA
CCAGCTGCTGCGCCTAA

Protein sequence :
MDENTWDLVVVGTGAAAMAAGIEARSRGKRVLLVEHGPLGGTCLNIGCIPSKNLLAAAGQRHRALANPFPMVPTTAGEVD
VPALMGRKQDLIDGLRQAKYEDVAAAHGFPIRHGHARFVDEATLHVEDEPVRAAAYVIATGAAPHLPDLPGLHDVAYLTS
TTAMEQQQLPASMVVIGGGYVGLEQAQLWSHLGVHVTLIGRVAPHTEPEVADVLRAAFLTDGIQLLEEHAVAVERGADDT
VLVHTASGRTANGERLLVATGRAADTTGLGLDDAGVATDARGFIVVDTHQRTTNPRIYAAGDVTGAPQYVYVAARTGHAA
AAGALGDPTAVDYRGLPGVVFTTPQLASAGLTEQRALELGHTCDCRVLTAQDIPRALVNQDPRGVLKLVTDAHTRQILGV
HAALDGAGELMLAATYAIKFGLTIDDIADTWAPYLTMSEALRLAAGLFRTNIPTSCCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 8e-66 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 6e-66 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 6e-66 41
merA AGK07021.1 MerA Not tested SGI1 Protein 7e-70 41
merA AGK07079.1 MerA Not tested SGI1 Protein 7e-70 41
merA ABQ57371.1 MerA Not tested SGI1 Protein 7e-70 41
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-66 41
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-66 41
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 2e-66 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cfla_3663 YP_003638733.1 mercuric reductase BAC0224 Protein 2e-83 44
Cfla_3663 YP_003638733.1 mercuric reductase BAC0652 Protein 2e-68 41