Gene Information

Name : Bmur_2315 (Bmur_2315)
Accession : YP_003634587.1
Strain : Brachyspira murdochii DSM 12563
Genome accession: NC_014150
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2619047 - 2620591 bp
Length : 1545 bp
Strand : +
Note : KEGG: bhy:BHWA1_02581 bifunctional GMP synthase/glutamine amidotransferase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; tRNA methyl transferase-like; glutamine amidotransferase class-I

DNA sequence :
ATGCAAAACAATATAGATAAGGTTTTAATACTAGATTTCGGCTCACAATTTACTCAGCTTATTACAAGAAGAATAAGGGA
ATTAAATGTTTATTCAGAGATACACCCTTTTCATGTTTCAATAGATTTTATAAAAGAATTCAATCCTAAAGCAATAATAC
TTTCAGGAGGTCCTTCAAGCGTGTATGAAGAAGATGCTCCTAAAGTAGATAAAGCATTATTTGAATTAGGTATTCCTATA
CTTGGTATATGTTATGGTATGCAGATAATAGTATATTCTATGGGCGGAAAAGTTGAAAGTGCTTCAAAAAGAGAATATGG
AAAAGCAGAAATAGAAATAACTAATCATGAGAGCATATTCAAATCATTTGATAAAAAAAATATAGTATGGATGAGCCATG
GAGACAGTATTAAATCTATACCAGAAGGTTTTGAGCTTATAGCAAAAACCCCTAATACGGAACTTGCTGCTATAGAAAAT
AAACAAAAAAATATTTATGCTATACAGTTTCACCCTGAGGTTGTTCACACTGAAAATGGTATAAAAATTATAGAGAATTT
CCTTTTTAATATTTGTAAATGCGAGAAAAATTGGAATATGGGTTCCTTTATAGAATATGAGGTTAATAGAATAAAAGAGA
GAGTAGGGGATAAAAACGTAATACTTGGGCTTTCTGGAGGAGTTGATTCTTCAGTGGCTGCTGTATTAATAGAAAAAGCT
ATAGGAAAACAACTTAAATGCATATTTGTAAATAATGGACTTTTAAGAAAAGATGAAGATAAAAAAGTAGTAGAAGTATT
CAGAGATAATTTTAATATTGATTTGATATATGTTGATGCTTCAAAGAGGTTTTTAGACAAATTGGCAGGTGTTACAGACC
CAGAGCAAAAAAGAAAAATAATAGGTCATGAATTTGTAAGTGTATTTAATGATGAAGCTAAAAAGATAGAGAATGTAGGA
TTTTTAGCACAGGGTACTCTTTATCCAGATGTAATAGAGAGTGTATCATTAAGGGGAAGTTCTGCTGTTATAAAAAGCCA
TCATAATGTAGGCGGACTTCCGAAAGATATGAAATTTGAACTTTTAGAGCCTTTCAGAGAATTATTCAAAGATGAGGTTA
GAGAAATTGGGCTTGAATTAAAATTACCAGAAGATATTGTATACAGACAGCCTTTTCCCGGACCTGGTCTTGCCGTTAGA
ATACTTGGAGATATCACAGAAGAGAGAGTAAAAATACTTCAGGAGGCTGATGATATAGTTGTAGCTGAAATAAAACATGC
AGGACTTTACAGAAAATTATGGCAGTCATTTGCTGTACTTCTTCCGGTAAAAAGTGTTGGCGTTATGGGAGACGGCAGAA
CTTATGAACAGGTTTGTGCTGTAAGAGCAGTTGAGAGTGTTGATGCTATGACTGCAGATTGGGCTAAAATCGATTATAAT
GTATTAGGTATAATATCAAACAGAATAATAAATGAAGTAAAAGGTATTAACCGTGTTGTTTATGATATATCTTCAAAACC
GCCTGCTACAATAGAATGGGAATAA

Protein sequence :
MQNNIDKVLILDFGSQFTQLITRRIRELNVYSEIHPFHVSIDFIKEFNPKAIILSGGPSSVYEEDAPKVDKALFELGIPI
LGICYGMQIIVYSMGGKVESASKREYGKAEIEITNHESIFKSFDKKNIVWMSHGDSIKSIPEGFELIAKTPNTELAAIEN
KQKNIYAIQFHPEVVHTENGIKIIENFLFNICKCEKNWNMGSFIEYEVNRIKERVGDKNVILGLSGGVDSSVAAVLIEKA
IGKQLKCIFVNNGLLRKDEDKKVVEVFRDNFNIDLIYVDASKRFLDKLAGVTDPEQKRKIIGHEFVSVFNDEAKKIENVG
FLAQGTLYPDVIESVSLRGSSAVIKSHHNVGGLPKDMKFELLEPFRELFKDEVREIGLELKLPEDIVYRQPFPGPGLAVR
ILGDITEERVKILQEADDIVVAEIKHAGLYRKLWQSFAVLLPVKSVGVMGDGRTYEQVCAVRAVESVDAMTADWAKIDYN
VLGIISNRIINEVKGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-151 58
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-151 58
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-152 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-126 50