Gene Information

Name : afeA (MCR_1867)
Accession : YP_003628016.1
Strain : Moraxella catarrhalis RH4
Genome accession: NC_014147
Putative virulence/resistance : Virulence
Product : chelated iron ABC transporter substrate binding protein AfeA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 1830309 - 1831235 bp
Length : 927 bp
Strand : +
Note : -

DNA sequence :
ATGAAATCAATCAAAACTTTTACCGCCTGTCTTACGATGTGCTTAGCCTTGGTTGGGTGCGGTCAGCAGACCAAAGAAGA
CATCAACGCACAGGATACTCATTCTCCAAAAAAACTGTCTGTTGTCACAACTTTTACTGTCATTGCTGACATTGCCCAGA
ATGTTGCTGGAGAGGCTGCCGATGTTCAATCCATTACCAAGGCAGGTGCTGAAATTCATGAATATGAACCCACGCCTCAA
GATGTGGTTAAAGCCCAAAAAGCAGATTTGATTTTATGGAATGGACTTAATCTAGAGCTTTGGTTTGAAAAATTTTATCA
TGATACCAGCAATGTGCCTGCCGTTGTTGTGACACAGGGTATCACACCGATTAACATCACTGAAGGTGCTTATAAAGACA
TGCCAAACCCACATGCTTGGATGTCGCCAAGTAATGCCTTGATTTATGTTGAGAATATCAAAAATGCACTCATTAAGCAA
GACCCAGCCAATCAGGAAGTTTATACCAAAAATGCTGAGCAGTACAGTGCAAAAATTAAAGCTATGGACGCTCCACTGCG
TGCCAAATTATCACAAATCCCTGAAAATCAGCGTTGGTTGGTAACCAGTGAAGGTGCGTTTAGCTACTTGGCCAACGATT
ACGGTCTTAAAGAAGCTTATTTGTGGCCAATTAATGCCGAACAGCAAGGCTCGCCTCAACAAGTCAAATCATTGATTGAT
ACGGTACGCAGCAATAACATTCCTGTGGTATTTAGTGAAAGTACAATTTCAGACAAACCAGCAAAACAAGTTGCCAAAGA
AACAGGTGCCAAATATGGCGGTGTACTTTATGTTGATTCACTGTCTGAAGCTGGCGGTCCTGTACCAACTTATCTTGACT
TATTACAAACCACCGTCTCAACCATCGCCAGCGGTTTTGAAAAGTGA

Protein sequence :
MKSIKTFTACLTMCLALVGCGQQTKEDINAQDTHSPKKLSVVTTFTVIADIAQNVAGEAADVQSITKAGAEIHEYEPTPQ
DVVKAQKADLILWNGLNLELWFEKFYHDTSNVPAVVVTQGITPINITEGAYKDMPNPHAWMSPSNALIYVENIKNALIKQ
DPANQEVYTKNAEQYSAKIKAMDAPLRAKLSQIPENQRWLVTSEGAFSYLANDYGLKEAYLWPINAEQQGSPQQVKSLID
TVRSNNIPVVFSESTISDKPAKQVAKETGAKYGGVLYVDSLSEAGGPVPTYLDLLQTTVSTIASGFEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitA NP_806464.1 iron transporter periplasmic-binding protein Virulence SPI-1 Protein 1e-90 66
sitA NP_461782.1 periplasmic binding protein Virulence SPI-1 Protein 1e-90 66
sitA AAD41065.1 SitA Virulence centisome 63 pathogenicity island Protein 1e-90 66
sitA YP_217781.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-90 66
sitA NP_457255.1 Iron transport protein, periplasmic-binding protein Virulence SPI-1 Protein 1e-90 66

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeA YP_003628016.1 chelated iron ABC transporter substrate binding protein AfeA BAC0439 Protein 4e-99 69
afeA YP_003628016.1 chelated iron ABC transporter substrate binding protein AfeA BAC0349 Protein 6e-91 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
afeA YP_003628016.1 chelated iron ABC transporter substrate binding protein AfeA VFG0525 Protein 5e-91 66