Gene Information

Name : hsdR2 (THI_0955)
Accession : YP_003623498.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Unknown
Product : Type I site-specific deoxyribonuclease HsdR
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.21.3
Position : 952021 - 955122 bp
Length : 3102 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8921897; Product type e : enzyme

DNA sequence :
ATGAGCATCCTCAACGAAGACCACCTCGAACAAGCCACACTCCAGTGGCTCTCTGCCCTTGGCTGGCAAACCGCCCACGG
CCCCGACATCTCTCCACCTGACGCCAAGACCCACGGGACCGAACGCGACACTTACCGCCAAGTCTGCCTGTCGCATCGGA
TTGAGGCCGCCATTCAACGCCTCAATCCTGGCATCCCCTCCACGGCGCAAGTCGAGGCCCTCCGCCAAGTCCTGAGCCCG
AACACTCCCGGCCTCATCGCCGCCAACCGCCAGTTCCACCGCTGGCTCGTCGAAGGTGTCCCAGTCGAATATCAGAAGGA
CGGAGAAACCCGTGGCGACCGTGTACGGCTCATCGACTTCAGCGACGTTGGGCGAAACGACTGGCTTGCAGTCAACCAGT
TTTCCATCCAGGGTCCAAAACACACCCGCCGTCCCGACGTCATCCTGTTCATCAACGGCCTGCCCCTAGTCACGCTGGAG
CTCAAGAACCCCGGCGACGAGAACGCCGACATCTGGGGCGCATTCAACCAGCTCCAAGCCTACAAAGAGGATATCCCTGA
CCTGTTTGTCTACAACGAGTTGCTGGTCATCACCGACGGCATTTCCGCTCGTCTGGGTTCGCTCACCGCGAACCGCGAGC
GATTCATGGCCTGGCGCACGATTGATGGTCACGCCACCGACCCGCTTGGGCCCATGCGTGAGCTGGAAACCTTGGTCCAC
GGGGCCTTCGACCGTAAGACGCTGCTCGATTACCTGCAGCACTTCATCCTGTTCGAGGACGATGGCGGCCTGGTCAAGAA
GGTTGCCGGCTACCACCAATTCCACGCCGTGCGCGCGGTGGTCGAGAGCGTGCTGAAAGCCAGCGCCCCCGGTGGCTCAC
GCAAGGGCGGGGTGGTCTGGCACACCCAGGGGGCGGGCAAAAGCATCGAGATGACCTGTCTGGGGGGCATGCTGATGCAG
AACCCGCAGATGGGCAACCCAACCCTGCTGGTCGTCACCGACCGCAATGACCTGGACAACCAGTTGTTCGGCGTGTTCGC
CGGCGCTACCGAGCTCCTCCATGAAACCCCGGTGCAGGCCGACACCCGCCCCCGCCTGCGAGAACTGCTGGGCAACCGCC
CCAGCGGTGGCATCGTGTTCACCACCATCCAAAAGTTCGCACCAGGGGAGGACGAAGACACGTTCCCGGTGCTGTCTGAG
CGCAGCAATATCGTCGTCGTTTGCGACGAAGCCCACCGCAGCCAGTACGGATTCAGCGCCGATATCAAAAAAGACGGCAA
AGTCACCTATGGCTACGCGCAATATCTGCGCGATGCCTTGCCCCAGGCTACCTTTGTCGCCTTTACCGGCACGCCGGTCT
CGCTCGAAGACCGCGACACCCGTGCGGTGTTCGGCGACTACGTCCACATCTATGACGTCGAGCAGGCGGTCAAGGATGGC
GCCACTGTGCCCATTTACTATGAATCCCGCCTTGCCAAGCTGGAACTCAGCGAGGAGAGCTCCACGCTCCTGGACGGCGA
CATCGACGAGTTGACCGAGGACGAAGAGGACGATGCCAGCAAGGCGGCCAAGCTGCGCCGCTGGGCTGCGCTGGAAAAAC
TCGTTGGCGCACCGCCCCGGATTCAGAAGGTGGCCGCCGATATCGTGGAGCACTTCGAAAACCGCCTTGCCGCCCTGGAC
GGTAAGGCCATGGTGGTCGGCATGAGCCGCGAGATTTGCGTCCATCTCTACGATGCCCTCGTCGCCCTGCGGCCGGAATG
GCACGACCCCGACCCTGACAAGGGCGCCATCAAAATCATCATGACGGGTTCGGCCTCGGATAAACCGATGCTCAAGCCGC
ACATCTACACCAAAGAGGTCAAGAAACGTCTGGAGCGGCGGTACAAAGACCCCGCCGACCCGTTCAAGTTGGTCATCGTG
CGCGATATGTGGCTCACCGGCTTTGACGCGCCATGTATGCACACGATGTACATCGACAAGCCCATGCGCGGCCACAGCCT
GATGCAGGCCATCGCCCGGGTGAACCGTGTGTTCAAGGACAAGCCCGGCGGCCTGGTGGTCGACTACATCGGCATTGCCA
ACGAACTCAAGGCCGCCCTGAAGGACTACACCTTGGCCCATGGCAAAGGCCGGCCGACCATCGACACGCACGAGGCCCTG
CGCTTGCTGCTGGAGAAGATGGAGGTCCTTCACGGCATCCTGCACGGCTGCGACTATGCGGACTTCCGCGCCCAGGCTTG
GCAGTTGCTGCCCAAGGTAGCCAACCATATCCTGGGCCAGGATGATGGCAAGAAGCGCTTTGCCGATGCCGTGCTCTCCG
CAAGCAAAGCCTTTGCCTTGTGCTGCACGCTCGACGAAGCTCTGGAGCATCGCGACGAGCTTGCCTTCCTGCAGGCAGTC
AAGGCGGCCCTGACCAAGCACACCACCCAGGACAAGAAACTCAGCGACGAGCAGAAGGAACACGCACTCCGGCAAATTCT
CAGCAAGGCCGTGGTCAGCGCCGAGGTCGTCGACATCTTCCAGGCCGCAGGGCTGAACAAGCCAGACATCGGCATTCTGT
CGGACGAGTTTCTGGACGATGTGCGGCACATGAAGGAGCGCAACCTGGCGGTCGAGCTGCTTGAGCGTCTGCTCAAGGAT
GACATCAAAACTCGCTTCAAGACCAATGTCGTCAAGGCGGCCAAGTACTCCGAGCTGTTGCAGGAAAGCCTCAAGCGCTA
CCAAAACCGCGCGATTGAAACCGCGCAGGTCATCGAAGAACTCATCGCCATGGCCAAGCAATTCCACGAGGAGGCCATTA
AAGGCGCTGCGTTGGGGCTAAGCCCTGACGAGAGGGCGTTCTACGACGCTTTGGCTGCCAATGAGTCGGCGGTGCGGGAA
CTGGGCGACGAGACTCTGAAGAAGATTGCGGTCGAGTTGACGCTGAAACTGCGTAACTCGGTAACCGTGGACTGGTCGGT
GAGAGATTCGGTGCGCGCCAGCCTGCGGGTGATGGTCAAGACGTTGTTACGGCGTTACAAGTATCCGCCGGATAAACAGG
AAGAGGCGACTGAGACGGTGCTCCGGCAGGCAGAGATGCTGTCGGCGGAGTGGGTGGCATGA

Protein sequence :
MSILNEDHLEQATLQWLSALGWQTAHGPDISPPDAKTHGTERDTYRQVCLSHRIEAAIQRLNPGIPSTAQVEALRQVLSP
NTPGLIAANRQFHRWLVEGVPVEYQKDGETRGDRVRLIDFSDVGRNDWLAVNQFSIQGPKHTRRPDVILFINGLPLVTLE
LKNPGDENADIWGAFNQLQAYKEDIPDLFVYNELLVITDGISARLGSLTANRERFMAWRTIDGHATDPLGPMRELETLVH
GAFDRKTLLDYLQHFILFEDDGGLVKKVAGYHQFHAVRAVVESVLKASAPGGSRKGGVVWHTQGAGKSIEMTCLGGMLMQ
NPQMGNPTLLVVTDRNDLDNQLFGVFAGATELLHETPVQADTRPRLRELLGNRPSGGIVFTTIQKFAPGEDEDTFPVLSE
RSNIVVVCDEAHRSQYGFSADIKKDGKVTYGYAQYLRDALPQATFVAFTGTPVSLEDRDTRAVFGDYVHIYDVEQAVKDG
ATVPIYYESRLAKLELSEESSTLLDGDIDELTEDEEDDASKAAKLRRWAALEKLVGAPPRIQKVAADIVEHFENRLAALD
GKAMVVGMSREICVHLYDALVALRPEWHDPDPDKGAIKIIMTGSASDKPMLKPHIYTKEVKKRLERRYKDPADPFKLVIV
RDMWLTGFDAPCMHTMYIDKPMRGHSLMQAIARVNRVFKDKPGGLVVDYIGIANELKAALKDYTLAHGKGRPTIDTHEAL
RLLLEKMEVLHGILHGCDYADFRAQAWQLLPKVANHILGQDDGKKRFADAVLSASKAFALCCTLDEALEHRDELAFLQAV
KAALTKHTTQDKKLSDEQKEHALRQILSKAVVSAEVVDIFQAAGLNKPDIGILSDEFLDDVRHMKERNLAVELLERLLKD
DIKTRFKTNVVKAAKYSELLQESLKRYQNRAIETAQVIEELIAMAKQFHEEAIKGAALGLSPDERAFYDALAANESAVRE
LGDETLKKIAVELTLKLRNSVTVDWSVRDSVRASLRVMVKTLLRRYKYPPDKQEEATETVLRQAEMLSAEWVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 58
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 47
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 46
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 46