Gene Information

Name : hsdM2 (THI_0952)
Accession : YP_003623495.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Unknown
Product : type I restriction-modification (R-M) system HsdM
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 948635 - 950200 bp
Length : 1566 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8921897, 8939428; Product type e : enzyme

DNA sequence :
ATGAACCAAGACCTAAAAAAAACCCTCTGGGCCACGGCAGACAAATTGCGTTCCAGCATGGACGCGGCCGAATACAAGCA
CATCGTTCTCGGCCTCATCTTCATCAAATACATCTCCGACGCATTCGATGAGCGCCGCGAGCAGCTCAAAGCCCAGTTCA
ACGACCCGGCTTCTGACCTCTACCTGCCCGATGCGGCAGACCAAGAGGCAGCGTTGGAGGAGCGCGATTACTACACGATG
GCCAACGTCTTCTGGGTGCCCGAAGCCGCCCGGTGGGAGACACTGCGTGGTCAGGCCAAGTTCTGGGACATCGGCATCCG
CATAGACCAGGCACTGGACGCCATCGAGGCCGATAACCCGCGCCTCAAGGGCATTCTGGACAAGCGCTTTGGTCGCGCCC
AACTGGAACCCGGCAAGATGGGAGAGTTGGTGGACCTCGTTTCCACCATCGGCTTCGGCTCGGGCACCCATGCCAAAGAT
GTGCTGGGGGAGGTCTACGAGTATTTCCTTGGACAGTTCGCCAGCGCTGAAGGCAAGAAGGGCGGGCAGTTCTACACCCC
AGCCTCTGTCGTCAAGGTCTTGGTCGAAGTACTCGCGCCGCACAAGGGCAAAGTCTACGACCCCTGCTGCGGTTCGGGCG
GCATGTTCGTACAGAGTGAGAAATTCATCGAGAGCCACGGCGGACGCTTTGGCGACATCTCTATCTATGGTCAGGAGGCC
AACCCCACGACCTGGCGCCTAGTCGCCATGAACTTGGCCATCCGGGGGATGGACTTCAACCTCGGCAAGGAACCCGCCGA
CACCTTCCACCGCGACCAGCACCCCGACCTCAAGGCCGACTATGTGTTGGCCAATCCCCCATTCAACATCTCCGATTGGG
GCGGGGACCGGCTACTGGATGACAAGCGCTGGCTCTATGGCACGCCCAACCCGAGCAATGCGAACTACGCCTGGCTGCAG
CACATCCTCTGGCACCTGAACGCCAGCGGGCAAGCCGGCGTGGTGCTGGCCAATGGCAGCATGTCGTCCAACCAAAATAA
TGAAGGCGTCATCCGCAAGGCCATGGTCGAAGCCGACGTCGTGGAGGTAATGGTGGCGCTGCCGCCACAGCTCTTTTTCA
ACACCCAGATTCCAGCCTGCCTGTGGTTTCTCACCAAGAGCAAAACCGCCCATGGCCGTGACCGCAGGGGAGAGGTGTTG
TTCATCGATGCCCGCAAGCTGGGGCGCATGGAAGGCCGGGTGTTTCGAGTGTTCGACGATGAGGATGTGGCCAAGATTGC
CGACACGGTGCATCGCTGGCGGCAGGATGGTCAGCTCGAGGGCCAGGAGCCCTATGCCGATGTGCCAGGCTTCTGCCGCG
CGGTGAAACTGACCGAGATTGCCGAACACGGCCATGTCCTCACGCCGGGGCGTTATGTCGGTGCCGAGGCTGTGGACGAT
GACGATGAGGCGTTCAGCGAGAAGATGGAACGGCTGACGGCACAACTCTCTGAGCAGATGGCGAAAGGCGCGAAGCTGGA
TGCGGTGATTCGCGAGAAGCTGGGGGGGCTGGGGTATGCGGTCTGA

Protein sequence :
MNQDLKKTLWATADKLRSSMDAAEYKHIVLGLIFIKYISDAFDERREQLKAQFNDPASDLYLPDAADQEAALEERDYYTM
ANVFWVPEAARWETLRGQAKFWDIGIRIDQALDAIEADNPRLKGILDKRFGRAQLEPGKMGELVDLVSTIGFGSGTHAKD
VLGEVYEYFLGQFASAEGKKGGQFYTPASVVKVLVEVLAPHKGKVYDPCCGSGGMFVQSEKFIESHGGRFGDISIYGQEA
NPTTWRLVAMNLAIRGMDFNLGKEPADTFHRDQHPDLKADYVLANPPFNISDWGGDRLLDDKRWLYGTPNPSNANYAWLQ
HILWHLNASGQAGVVLANGSMSSNQNNEGVIRKAMVEADVVEVMVALPPQLFFNTQIPACLWFLTKSKTAHGRDRRGEVL
FIDARKLGRMEGRVFRVFDDEDVAKIADTVHRWRQDGQLEGQEPYADVPGFCRAVKLTEIAEHGHVLTPGRYVGAEAVDD
DDEAFSEKMERLTAQLSEQMAKGAKLDAVIREKLGGLGYAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 3e-134 53
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 4e-136 53
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-123 53
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-135 52