Gene Information

Name : hsdM1 (THI_0612)
Accession : YP_003623198.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Unknown
Product : type I restriction-modification (R-M) system HsdM
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 614395 - 615960 bp
Length : 1566 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8921897, 8939428; Product type e : enzyme

DNA sequence :
ATGAACCAAGACCTCAAGAAAACGCTCTGGGCCGCCGCCGACAAGCTGCGCTCCAGCATGGACGCCGCCGAGTACAAGCA
CATCGTGCTTGGGCTCATCTTCATCAAATACATCTCTGACGCATTCGACGAGCGCCGCGAGCAACTCAAAACCCAGTTCA
ACGACCCCGCGTCCGACCTGTACCTGCCCGATGCGGCCGACCAGGCCGCCGCGCTGGAGGAGCGCGATTACTACACCATG
GCTAATGTGTTCTGGGTGCCCGAGGTCGCGCGCTGGGAGACCCTGCGCGCCCAGGCCAAGCTCTGGGACATCGGCATCCG
CATCGACCAGGCACTCGACGCCATCGAGGCCGACAACCCGCGCCTCAAGGGCATCCTGGACAAGCGCTACGGCCGCGCCC
AACTGGAGCCGGGCAAGATGGGCGAGCTGGTGGACTTGGTCTCCACCATCGGCTTCGGCACGGGCACCCAGGCCAAAGAC
GTCCTGGGCGAGGTGTACGAGTATTTCCTCGGCCAGTTCGCCAGCGCCGAGGGCAAGAAGGGCGGGCAGTTCTACACCCC
GGCCTCGGTGGTCAAGGTGCTGGTCGAAGTGCTCGCACCGCACCAAGGCAAGGTCTACGACCCCTGCTGCGGGTCGGGTG
GCATGTTCGTGCAGTCCGAGAAGTTCATCGAGAGCCACGGCGGGCGCTTTGGCGACATCTCCATCTACGGCCAGGAGGCC
AACCCCACGACCTGGCGCCTAGTGGCGATGAACTTGGCCATCCGGGGCATGGACTTCAACCTCGGCAAGGAACCCGCCGA
CACCTTCCACCGCGACCAGCACCCCGACCTCAAGGCCGACTACGTGCTGGCCAATCCGCCGTTCAACATCTCCGACTGGG
GCGGCGACCGCCTGCTGGACGACAAGCGCTGGCTCTACGGCACGCCCAACCCGAGCAATGCGAACTACGCCTGGCTGCAG
CACATCCTCTGGCACCTGAACGCCAACGGGCAGGCCGGCGTGGTGCTGGCCAACGGCAGCATGTCGTCCAACCAGAACAA
CGAAGGCACCATCCGCAAGGCCATGGTCGAGGCCGACGTGGTGGAAGTCATGGTGGCGCTGCCGCCGCAACTCTTCTTCA
ACACCCAGATTCCCGCCTGCCTGTGGTTCCTGACCAAGAGCAAGACCGCCCATGGCCGCGACCGCAGGGGCGAGGTGCTG
TTCATCGATGCCCGCAAGCTCGGGCGCATGGAGACCCGTGTCAACCGCGTGTTCGATGACGAGGACGTGGCCAGGATTGC
CGGCACGGTGCATCGCTGGCGACAGGATGGGGAGGCTGGTGCGCAAGAGCCCTATGCCGATGTGCCGGGATTCTGCCGCG
CGGTGAAGCTGGCCGAGATTGCCGAACACGGCCATGTGCTCACGCCGGGGCGGTATGTGGGCGCGGAGGCGGTGGATGAT
GACGATGAGGCGTTCAACGAGAAGATGGAGCGGCTGACCACCTTGCTTGCCGAGCAGATGGCGAAAGGCGCGGAGCTCGA
TGCGGTGATTCGGGAGAAGCTGGGGAGGATTGGGTATGCGGTTTGA

Protein sequence :
MNQDLKKTLWAAADKLRSSMDAAEYKHIVLGLIFIKYISDAFDERREQLKTQFNDPASDLYLPDAADQAAALEERDYYTM
ANVFWVPEVARWETLRAQAKLWDIGIRIDQALDAIEADNPRLKGILDKRYGRAQLEPGKMGELVDLVSTIGFGTGTQAKD
VLGEVYEYFLGQFASAEGKKGGQFYTPASVVKVLVEVLAPHQGKVYDPCCGSGGMFVQSEKFIESHGGRFGDISIYGQEA
NPTTWRLVAMNLAIRGMDFNLGKEPADTFHRDQHPDLKADYVLANPPFNISDWGGDRLLDDKRWLYGTPNPSNANYAWLQ
HILWHLNANGQAGVVLANGSMSSNQNNEGTIRKAMVEADVVEVMVALPPQLFFNTQIPACLWFLTKSKTAHGRDRRGEVL
FIDARKLGRMETRVNRVFDDEDVARIAGTVHRWRQDGEAGAQEPYADVPGFCRAVKLAEIAEHGHVLTPGRYVGAEAVDD
DDEAFNEKMERLTTLLAEQMAKGAELDAVIREKLGRIGYAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 4e-135 53
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 3e-133 53
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-133 52
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-121 52