Gene Information

Name : aldB (THI_0486)
Accession : YP_003623089.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.-
Position : 494053 - 495573 bp
Length : 1521 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15659684, 7768815; Product type e : enzyme

DNA sequence : 
ATGGATATGCTTGAACCCGGTAAGTTTGGTACCGCTGTTGCCTTCAAAAAGCGTTACGGCAACTACATTGGCGGCGAATG
GGTTGCCCCTGCCGGTGGCCAATATTTCGAAAACATTTCGCCCGTTACTGGCAGGCCGTTCTGCGAGATCCCGCGTTCGA
CCGCACCCGATATCGAACATGCGCTCGATGCGGCGCACAAGGCTAAAGGAGCCTGGGGCCGCACATCGCCCACGGACCGG
GCAAATATCCTGAACAAGATTGCCGACCGTATGGAAGCCAATCTCCCCATGCTGGCTGCCGCCGAGACCTGGGACAACGG
AAAACCCATCCGCGAAACAACGCTGGCGGATCTGCCCCTCGCTGTCGATCACTTCCGCTATTTCGCGTCGTGCGTGCGTT
CCCAGGAAGGTGGCATCAGCGAGATTGACCATGACACCTACGCCTACCACTACCACGAGCCGATCGGCGTGGTTGGGCAG
ATCATTCCCTGGAACTTTCCGATTCTGATGGCAGTCTGGAAACTGGCGCCCGCGTTGGCTGCGGGAAACTGCGTTGTGCT
CAAGCCCGCCGAGCAAACGCCGGTGTCCATCCTGGTGCTCGTGGAATTGGTCGGGGACCTCCTGCCTCCGGGCGTCCTCA
ACGTGGTCAACGGCTTCGGCCTGGAAGCGGGCAAGCCATTGGCATCGAGCAGCCGCATCGGCAAGATCGCCTTCACGGGC
GAGACGACCACCGGCCGCCTGATTTCGCAGTATGCGAGCCAGAACCTGATTCCCGTGACACTGGAACTGGGTGGCAAATC
GCCGAACATCTTCTTTGCCGATGTGATGGACAAGGACGATGGCTACTTCGACAAGGCGCTTGAAGGCTTCGCGATGTTCG
CGCTCAACCAGGGTGAAGTCTGCACCTGCCCGTCGCGCGCGTTGATCCAGGAGTCGATCTATGACCGATTCATGGAGCGC
GCAATCAAGCGCGTAGCAGCAATCAAGCAGGGAAATCCGCTGGATATGGACACCATGATCGGCGCGCAGGCGTCAAGCGA
GCAACTGGAGAAGATCGTTTCATATCTCGACATTGGCAAACAGGAGGGTGCCCAGGTGCTGATTGGCGGTGAGCGCAACA
AACTCCCGGGAGACCTCGAAGGCGGCTATTACGTCAAGCCCACGGTCTTCAAAGGGAACAACAAAATGCGCATTTTCCAG
GAGGAGATCTTCGGCCCTGTCCTGTCCGTTACCACCTTCAAGGACGAGGAAGAAGCACTGGAAATCGCTAATGACACGCT
GTATGGACTGGGCTCGGGGGTCTGGACGCGCGACATGAATCGGGCGTTCCGCATGGGCCGCGGCATCCAGGCTGGCCGCG
TCTGGACGAATTGCTACCACCTTTACCCTGCCCATGCGGCATTCGGTGGTTACAAGCAATCGGGTATCGGACGCGAAAAC
CACAAGATGATGCTCGACCATTATCAGCAGACCAAGAACCTGCTAGTGAGCTACAGCGAAAGCAAACTGGGCTTCTTTTG
A

Protein sequence : 
MDMLEPGKFGTAVAFKKRYGNYIGGEWVAPAGGQYFENISPVTGRPFCEIPRSTAPDIEHALDAAHKAKGAWGRTSPTDR
ANILNKIADRMEANLPMLAAAETWDNGKPIRETTLADLPLAVDHFRYFASCVRSQEGGISEIDHDTYAYHYHEPIGVVGQ
IIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTPVSILVLVELVGDLLPPGVLNVVNGFGLEAGKPLASSSRIGKIAFTG
ETTTGRLISQYASQNLIPVTLELGGKSPNIFFADVMDKDDGYFDKALEGFAMFALNQGEVCTCPSRALIQESIYDRFMER
AIKRVAAIKQGNPLDMDTMIGAQASSEQLEKIVSYLDIGKQEGAQVLIGGERNKLPGDLEGGYYVKPTVFKGNNKMRIFQ
EEIFGPVLSVTTFKDEEEALEIANDTLYGLGSGVWTRDMNRAFRMGRGIQAGRVWTNCYHLYPAHAAFGGYKQSGIGREN
HKMMLDHYQQTKNLLVSYSESKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-154 65
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-160 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-160 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-160 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-160 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_003623089.1 aldehyde dehydrogenase B VFG0082 Protein 3e-154 65