Gene Information

Name : lysU (THI_0429)
Accession : YP_003623041.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Virulence
Product : Lysyl-tRNA synthetase, heat inducible (Lysine--tRNA ligase) (LysRS)
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 439144 - 440673 bp
Length : 1530 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10913247, 2183178, 2188953, 7735833; Product type e : enzyme

DNA sequence :
ATGAATACTGACGCCCCCCATCCGCCCGCCGCTGACGACAGCCACCTCATCGCGGAGCGCCGCGCCAAACTCGCCGCGTT
GCGCGAGGTCGGTCCGGCGTTTCCGAATGATTTCAAGCCCACGCACCAGGCAGCCAGCCTGCAGGCGCAACTTGGGGGCG
ACGAGCCCGACGCGCCCGACGCGCTCGAAGCGGCTGGCGTGCGGGTGCGGGTGGCGGGCCGCATGATGCTCAAGCGCGTG
ATGGGCAAGGCCAGTTTTGCCACTTTGCAGGACGGTACGGGGCGCATTCAGATCCACGTTTCCAACGATGTCACTGGTGA
AGAGGCCCATGCCGCCTTCAAACACTACGACCTGGGCGACTGGATCGGTTGCGACGGCGTGCTGTTCAAAACGCGCACCG
GCGAGCTGACCATTCGGGCCGAGCAGGTGCGATTGCTGGTCAAGTCGCTGCGCCCCTTGCCCGACAAGTTTCACGGCCTC
GAAGACGTGGAAACGCGCTACCGCCAGCGTTATGTCGATCTCATCGTCACACCAGAATCGCGCGAACGCTTCGCGCTGCG
CAGCAAGGCCATCGCGGCGCTGCGCAACGAAATGCTGGCAGCGGGTTTCATGGAGGTTGAGACGCCCATGCTGCACCCCA
TTCCCGGAGGTGCTGCGGCCAAACCGTTCATCACGCACCACAACGCGCTCGATCAGCAGATGTATCTGCGCATCGCGCCC
GAGCTTTACCTCAAGCGCCTGCTGGTGGGCGGCTTCGAGCGGGTGTTCGAGATCAACCGCAATTTCCGCAACGAAGGCCT
GAGCCCGCGGCACAACCCCGAGTTCACCATGATGGAGTTCTACGCCGCCTGGTGGACCTACCGCGACCAGATGGATTTCA
CCGAGGCGCTGATTCGCAACACCGCGCAACTCACCTGCGGCACTGCGGTGCTCACCCACCAAGGGCGCACGCTGGACTTG
AGCGCGCCGTTTGCTCGGCTGACCTTGACGCAGGCCATCCAGAAGCACGCCCCCGACTACACCGACGCGCAACTGGCCGA
TGACGGCTTTTTGCGCGGCGAGTTGCGCCGTCTCGACGCCGATCACGCCCCGCACAAACTCAAGGGCATGGGACTGGGCG
CTTTGCAACTCGCGCTGTTTGAGCAAGTCGCCGAGCATATGCTGTGGGAGCCGACCTTCATCGTCGATTATCCGGTGGAA
GTGTCGCCCCTGGCCCGCGCCGCCGATGCCGATGCGAACACGACCGAGCGCTTCGAGCTGTTCATCACCGGCCGCGAAAT
CGCCAACGGCTTCTCCGAGCTGAACGACCCCGAAGACCAGGCCGCCCGCTTTCAGTCGCAAGTGCAGGCCAAGGAAGCCG
GCGACGACGAAGCCATGTATTTCGACGCCGATTATGTACGGGCACTGGAATACGGCATGCCGCCCGCCGGGGGCTGCGGC
ATCGGCATCGACCGGCTGGTCATGCTGCTCACCGACGCGCCCAGCATCCGCGACGTCATTCTCTTCCCCGCCCTGCGCTT
CGAAGGCTAA

Protein sequence :
MNTDAPHPPAADDSHLIAERRAKLAALREVGPAFPNDFKPTHQAASLQAQLGGDEPDAPDALEAAGVRVRVAGRMMLKRV
MGKASFATLQDGTGRIQIHVSNDVTGEEAHAAFKHYDLGDWIGCDGVLFKTRTGELTIRAEQVRLLVKSLRPLPDKFHGL
EDVETRYRQRYVDLIVTPESRERFALRSKAIAALRNEMLAAGFMEVETPMLHPIPGGAAAKPFITHHNALDQQMYLRIAP
ELYLKRLLVGGFERVFEINRNFRNEGLSPRHNPEFTMMEFYAAWWTYRDQMDFTEALIRNTAQLTCGTAVLTHQGRTLDL
SAPFARLTLTQAIQKHAPDYTDAQLADDGFLRGELRRLDADHAPHKLKGMGLGALQLALFEQVAEHMLWEPTFIVDYPVE
VSPLARAADADANTTERFELFITGREIANGFSELNDPEDQAARFQSQVQAKEAGDDEAMYFDADYVRALEYGMPPAGGCG
IGIDRLVMLLTDAPSIRDVILFPALRFEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-119 54
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 2e-75 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysU YP_003623041.1 Lysyl-tRNA synthetase, heat inducible (Lysine--tRNA ligase) (LysRS) VFG1668 Protein 6e-120 54