Gene Information

Name : ureC (THI_3578)
Accession : YP_003625933.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Virulence
Product : urease alpha subunit (Urea amidohydrolase alpha subunit)
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 3476272 - 3478011 bp
Length : 1740 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2182382, 2211515, 8121412, 9150240, 9524276; Product type e : enzyme

DNA sequence :
ATGGCCACGATCTCCCGCCGCGCCTATGCCGAGATGTACGGCCCCACCACCGGCGACCGCGTGCGCCTGGCCGACACTGA
CCTGCTCATCGAAGTGGAAGACGACTACACCCTGCGCGCCGGAGGCTATGGCGAAGAGGTGAAGTTCGGCGGCGGCAAAA
CCATCCGCGACGGCATGGGTCAGAGCCAGCGCACCCGCGCCGAAGGGGTGATGGATCTGGTCATCACCAATGCGCTCATC
CTCGACCACTGGGGCATCGTCAAGGCGGACGTGGGCATTCGTGGCCAGCGCATCGCCGCCATCGGCAAGGCGGGCAATCC
GGACGTGCAGCCGGGCGTGGACATCATCATCGGCCCGGGCACCGAAATCCTCGCGGGGGAAGGCATGATCCTCACCGCCG
GGGGTATCGACAGCCATATCCACTTCATCTGCCCGCAGCAGATCGAAGAGGCGCTGATGAGCGGCGTCACCACCATGCTG
GGCGGCGGCACCGGCCCGGCCACTGGCACCAACGCCACCACCTGCACCCCGGGGCCGGAAAACATCGCCCGCATGTTGCA
GGCGGCCGATGCCTTCCCGATGAACCTGGGTTTTCTCGGCAAGGGCAACGCCAGCCAGCCCGCGGCGCTGCGCGAGCAGA
TCGAGGCCGGCGCCATCGGCCTGAAGCTGCACGAAGACTGGGGCACCACGCCCGCGGCGATCGACTGCTGCCTCTCGGCG
GCAGAAGAGACCGATGTGCAGGTGGCCATCCACACCGATACGCTCAACGAGAGCGGCTTCGTCGAAGACACCATCGCGGC
ATTCAAGGGCCGCACCATCCATACCTTCCATACCGAAGGCGCGGGCGGTGGCCATGCGCCCGACATCCTGCGCGTGCTGG
GCGAGGCCAATGTGCTGCCGTCCTCCACCAACCCCACGCGGCCCTTTACCGTCAACACCATCGACGAGCACCTCGACATG
CTGATGGTGTGCCACCACCTCGACGCGGGCATCGCCGAAGATCTGGCTTTTGCTGAAAGCCGCATCCGCCGCGAGACCAT
TGCCGCCGAAGACGTGCTGCACGACCTCGGCGCCATCAGCATCATGTCCAGCGACAGCCAGGCCATGGGGCGCGTGGGCG
AAGTGGCGCTGCGCACCTGGCAGACCGCGCACAAGATGAAAGCGCAGCGCGGCTGGCTGGCGCCTCCGGCTTCGGGTGGC
GCCCAGGGCAATGACCGCAACGATAACTTCCGCGCCAAGCGCTACATCGCCAAATACACCCTCAACCCTGCACTGGCGCA
CGGCATCGCGCACGAAGTGGGCTCGGTGGAAGCGGGCAAATGGGCCGATCTGGTGCTGTGGCGCCCGGCGTGGTTCGGCG
TGAAGCCCAGCGTGATTCTCAAAGGCGGCTTCATCGCCGCCGCACTCATGGGCGACGCCAACGCGTCCATTCCCACGCCG
CAGCCTGTGCATACCCGTCCCATGTTCGGCGCCTTCGGCGGCGCGCGCACCGCCACCTCGCTGACCTTCGTGTCCCAGGC
CGCGCTGGCCAACGACATCGGCCAGCGTCTGGGCTTGCACAAGTCGCTCGCCGCCGTGCGCGACTGCCGCAGCGTGAAAA
AGGCCGACATGGTGCACAACGCCTACACCCCGCGCATGGAGGTGGACGCGCAGACCTACGAGGTGCGCGCCGACGGCGTG
CTGCTCACCTGCGAACCCGCGACCGTGCTGCCGATGGCGCAGCGATATTTCTTGTTTTGA

Protein sequence :
MATISRRAYAEMYGPTTGDRVRLADTDLLIEVEDDYTLRAGGYGEEVKFGGGKTIRDGMGQSQRTRAEGVMDLVITNALI
LDHWGIVKADVGIRGQRIAAIGKAGNPDVQPGVDIIIGPGTEILAGEGMILTAGGIDSHIHFICPQQIEEALMSGVTTML
GGGTGPATGTNATTCTPGPENIARMLQAADAFPMNLGFLGKGNASQPAALREQIEAGAIGLKLHEDWGTTPAAIDCCLSA
AEETDVQVAIHTDTLNESGFVEDTIAAFKGRTIHTFHTEGAGGGHAPDILRVLGEANVLPSSTNPTRPFTVNTIDEHLDM
LMVCHHLDAGIAEDLAFAESRIRRETIAAEDVLHDLGAISIMSSDSQAMGRVGEVALRTWQTAHKMKAQRGWLAPPASGG
AQGNDRNDNFRAKRYIAKYTLNPALAHGIAHEVGSVEAGKWADLVLWRPAWFGVKPSVILKGGFIAAALMGDANASIPTP
QPVHTRPMFGAFGGARTATSLTFVSQAALANDIGQRLGLHKSLAAVRDCRSVKKADMVHNAYTPRMEVDAQTYEVRADGV
LLTCEPATVLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 7e-169 70
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 7e-169 70
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-156 62
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-156 62
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-156 62
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-156 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_003625933.1 urease alpha subunit (Urea amidohydrolase alpha subunit) VFG0270 Protein 1e-147 62