Gene Information

Name : arsB2 (THI_3150)
Accession : YP_003625531.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Resistance
Product : Arsenical pump membrane protein (Arsenic efflux pump protein)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3067145 - 3068431 bp
Length : 1287 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15004242, 1535622, 7721697, 95355341; Product type t : transporter

DNA sequence :
ATGCCGACCGCGCTGCTGATTTTCATTGCCACCCTGGTACTGGTCATCTGGCAGCCGAAAGGTTTGGGCATCGGCTGGAG
CGCGACTTTCGGTGCCATTGCCGCCCTTCTGTCCGGCGTGATTCATCTCGCCGATATTCCGGCGGTTTGGCACATCGTTT
GGAACGCCACCATTACTTTCGTTGCCACCATCATCATCAGCCTGTTGCTCGATGAAGCCGGTTTTTTCGAGTGGGCGGCG
CTACGCGTGGCACGTTGGGGTCGCGGCAACGGACGCGGACTCTTCGCCTTCCTGGTCCTGCTGGGCGCAACCGTGGCGGC
CTTGTTCGCCAATGACGGCGCAGCGCTGATTTTGACGCCGATCGTGATGGCGATGCTGCTGGCGCTCGGGTTCAGTCCGG
CGGCGACACTGGCTTTCGTCATGGCCGCCGGCTTCATCGCCGATACGTCGAGCCTGCCATTGATGGTGTCCAATCTGGTC
AATATCGTCTCGGCCAATTTCTTCAACATCGGCTTCAACGCATACGCCGCGATCATGGTCCCGGTGGATATCGCCGCGAT
CGCCGCCAGCTTGGCAGCGCTCTTGCTCTATTTTCGCCCCAGTATCCCGATACGCTACGACATGGCTTTGCTCAAACATC
CCAACGCAGCAATCCTCGACCCTGCCACGTTCCGCATCGGGTGGGTGGTGCTGGCGCTCCTGCTGCTCGGGTACTTTGGT
CTTGAACCGCTGGGTGTGCCGGTCAGCGCCGTCGCGGTCTTCGGTGCGCTGCTGCTCCTCGGCGTGGCTGCGCGCGGCCA
TGTCATCAGCACCCGGAAGGTGTTGCGCGAAGCACCCTGGCAGATCGTCATTTTCTCGCTGGGGATGTATCTGGTGGTGT
ATGGCCTGCGCAACGCCGGAATCACTGGGTATCTGGCGGACCTGCTGAATGTTTTCGCCAACTATGGTGTCTGGGGCGCG
GCGTTTGGCACGGGCGTGCTGACGGCATTCCTCTCCTCGGTGATGAACAACATGCCAACGGTCCTTGTGGGTGCGCTCTC
CGTTGCTGCGACGAACGCCACCGGCCCGGTGCGCGAGGCCATGATCTATGCCAATGTCATCGGCTGTGATCTCGGCCCCA
AGTTCACACCCATCGGCAGTCTGGCCACCTTGCTCTGGCTGCACGTGCTCGCGCGCAAGGGCATGACCATCGGTTGGGGG
TATTACTTCAAGGTGGGTGTCCTGCTGACCGTGCCCGTCCTACTGATCACGCTGACCGCGCTCGCACTGCGTCTGAGTCT
GGCTTGA

Protein sequence :
MPTALLIFIATLVLVIWQPKGLGIGWSATFGAIAALLSGVIHLADIPAVWHIVWNATITFVATIIISLLLDEAGFFEWAA
LRVARWGRGNGRGLFAFLVLLGATVAALFANDGAALILTPIVMAMLLALGFSPAATLAFVMAAGFIADTSSLPLMVSNLV
NIVSANFFNIGFNAYAAIMVPVDIAAIAASLAALLLYFRPSIPIRYDMALLKHPNAAILDPATFRIGWVVLALLLLGYFG
LEPLGVPVSAVAVFGALLLLGVAARGHVISTRKVLREAPWQIVIFSLGMYLVVYGLRNAGITGYLADLLNVFANYGVWGA
AFGTGVLTAFLSSVMNNMPTVLVGALSVAATNATGPVREAMIYANVIGCDLGPKFTPIGSLATLLWLHVLARKGMTIGWG
YYFKVGVLLTVPVLLITLTALALRLSLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 6e-124 75
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-92 55
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 6e-92 55
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-93 55

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB2 YP_003625531.1 Arsenical pump membrane protein (Arsenic efflux pump protein) BAC0578 Protein 9e-122 75
arsB2 YP_003625531.1 Arsenical pump membrane protein (Arsenic efflux pump protein) BAC0576 Protein 2e-123 75
arsB2 YP_003625531.1 Arsenical pump membrane protein (Arsenic efflux pump protein) BAC0031 Protein 2e-122 74
arsB2 YP_003625531.1 Arsenical pump membrane protein (Arsenic efflux pump protein) BAC0577 Protein 3e-119 73
arsB2 YP_003625531.1 Arsenical pump membrane protein (Arsenic efflux pump protein) BAC0574 Protein 2e-93 56
arsB2 YP_003625531.1 Arsenical pump membrane protein (Arsenic efflux pump protein) BAC0575 Protein 2e-93 55