Gene Information

Name : hemC (THI_2268)
Accession : YP_003624725.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Unknown
Product : Porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase)
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.61
Position : 2219790 - 2220743 bp
Length : 954 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1522882, 1747120, 2025226, 2122889, 2510713, 3052434, 90056403, 93170293; Product type e : enzyme

DNA sequence :
ATGACTTCCACTTTCACTCCCCCACCGTCCCTCGTCATTGCCACCCGCGAAAGCCGTCTGGCGCTTTGGCAGGCCGAGCA
TGTGCGCGATCTGCTCAAGGGGCTGTATCCGCAGTGCGATGTGCGGATTTTCGGCATGACCACGCAGGGCGACCAGATTC
TCGACAAATCGCTGGCCAAGATCGGCGGCAAGGGGCTGTTCGTCAAGGAACTCGAAGTGGCCATGGAGCAGGGCCATGCC
GACCTCGCGGTGCATTCGCTCAAGGATGTGCCCATGGTGCTGCCGACCGGATTCGCGCTCACCGCGGTGATGGAGCGTGA
AGACCCGCGAGACGCCTGGGTCAGCCCGCATTACGCCAATCTGGCCGATCTGCCCGCGGGCGCGGTGGTCGGCACCTCCA
GTTTGCGGCGCGAATCGCAACTGCGCGCGCGCTATCCGCATCTGAAAGTGCAGGCGCTGCGCGGCAACCTCGACACCCGG
CTGCGCAAGCTCGACGAAGGGCAGTATGCCGGCATCCTGCTGGCGGCAGCGGGGCTCAAGCGGCTGGGTCTAGGCGAGCG
GGTGCGCGCTGTCATCGAACCTGAAGACATGCTCCCGGCTGTCGGGCAGGCGGCGCTGGGTATCGAAATTCGCGCCGACC
GGCCCGATCTGGCGCAGGCGCTGGCTGCGCTCAACCATCCGCCCACGGCCTTGTGCACCCATGCTGAGCGCGCGGTGTCG
CGGGGGCTGGGCGGTAGTTGCACCACGCCGATGGGCGCCTATGCCACATTGGAGGGCGAGGCAATGCATCTGCGCGCCGT
GTTGGGGCTGCCCGATGGCAGCCAGGCGCTGCACGCGCAGCAGCGTGGGCGCGTCACCGATCTGGCGCAGGCCGAGGCGC
TGGGGCAGCAGGTGGCGCGGCAGTTGCGCGAACAGGGCGCCGACGCGCTGCTGGCGCAACTCGGTTCGCATTGA

Protein sequence :
MTSTFTPPPSLVIATRESRLALWQAEHVRDLLKGLYPQCDVRIFGMTTQGDQILDKSLAKIGGKGLFVKELEVAMEQGHA
DLAVHSLKDVPMVLPTGFALTAVMEREDPRDAWVSPHYANLADLPAGAVVGTSSLRRESQLRARYPHLKVQALRGNLDTR
LRKLDEGQYAGILLAAAGLKRLGLGERVRAVIEPEDMLPAVGQAALGIEIRADRPDLAQALAALNHPPTALCTHAERAVS
RGLGGSCTTPMGAYATLEGEAMHLRAVLGLPDGSQALHAQQRGRVTDLAQAEALGQQVARQLREQGADALLAQLGSH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-61 54
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-61 54