Gene Information

Name : guaA (THI_2183)
Accession : YP_003624649.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Unknown
Product : GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase) (GMPS)
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 2137302 - 2138900 bp
Length : 1599 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2982857, 3894345, 85261223, 8548458; Product type e : enzyme

DNA sequence :
ATGCACGACAAAATTCTCATCCTCGACTTCGGCTCCCAGGTCACGCAACTCATCGCCCGCCGCGTGCGCGAGGCGCAGGT
GTACTGCGAAATTCACCCTTGCGATGTGAGCGATGCTTTCGTGCGCGAGTTCGCGCCCAAGGGCATCATTCTCTCGGGCA
GCCACGGCAGCACTTACGAAGACCACGAACTGCGCGCGCCGCAAGCCGTGTGGGATTTGGGCGTGCCCGTGCTGGGCATT
TGCTATGGCATGCAAACCATGGCGGCGCAACTGGGCGGCAAGGTGGAATGGAGCGACCACCGCGAGTTTGGTTATGCCGA
AGTGCGCGCCCGCGGTCACACCCGGCTGTTCGACGGCATCCAAGATTTCAGTACGGCCGAAGGCCACGGCATGCTCAAAG
TGTGGATGAGCCACGGCGACAAGGTGACCGATATGCCCCCGGGGTTCAAGCTCATGGCGTCCACGCCGAGTTGCGCCATC
GCGGGCATGGCCGACGAGGCGCGCGGTTACTACGCCGTGCAGTTTCACCCCGAAGTCACTCACACCGTGCAGGGCAGGGC
CATGCTCACACGTTTTGTGCGAGAGATCTGCGGCTGCCGTGGCGACTGGGTCATGGGCGATTACATCGCTGAAGCGGTGC
AGAGCATTCGCGCGCAGGTCGGTGATGAGGAGGTCATCCTCGGTCTGTCGGGCGGAGTCGATTCTTCGGTGGCGGCAGCG
CTGATTCACCGCGCCATCGGCGACCACCTCACCTGCGTGTTCGTCGATCACGGCTTGCTGCGCCTGAACGAGGGCGACCT
GGTGATGGACATGTTCGCGGGCAAGCTGCACGCCAAGGTGATTCGTGTGGACGCCAGCGAGCTGTTCCTGGGCCAGTTGG
CGGGCGTGACCGATCCCGAGAAAAAACGAAAGATCATCGGCGGGCTGTTCGTCGATGTGTTCAAGGCTGAGGCGGCCAAG
CTCAAAGGCGACGGCGCCAAGGGCGCGAAGTGGCTGGCGCAGGGCACCATCTACCCCGACGTGATCGAGTCGGGCGGCGC
CAAGAGCAAAAAGGCCGTCACCATCAAGAGCCATCACAACGTCGGTGGCCTGCCCGAGCAACTCGGCCTGAAACTGCTGG
AGCCCCTGCGCGAACTGTTCAAGGACGAAGTGCGCGAGTTGGGCGTGGCGCTGGGCCTGCCGCCCGACATGGTCTACCGC
CATCCCTTCCCCGGCCCGGGGCTGGGCGTGCGCATTCTGGGCGAGGTGAAGAAGGAGTACGCCGACCTGCTGCGCCGGGC
CGACGCCATCTTCATCGAAGAGTTGCGTTCGACCCTTGATCCAGATTCCGGCAAGAGCTGGTACGAGCTGACCAGCCAGG
CCTTCACCGTGTTCCTGCCGGTCAAGAGCGTGGGTGTGATGGGTGATGGCCGCACCTACGACTATGTGGTCGCGCTGCGC
GCGGTGCAGACCAGCGACTTCATGACCGCCGACTGGGCCGAGCTGCCCTATGCGCTGCTCAAAAAAGTGTCCAGCCGCAT
CATCAACGAGGTGCGCGGCATCAACCGCGTGACCTACGACGTGAGTTCCAAGCCGCCAGCGACCATCGAGTGGGAGTGA

Protein sequence :
MHDKILILDFGSQVTQLIARRVREAQVYCEIHPCDVSDAFVREFAPKGIILSGSHGSTYEDHELRAPQAVWDLGVPVLGI
CYGMQTMAAQLGGKVEWSDHREFGYAEVRARGHTRLFDGIQDFSTAEGHGMLKVWMSHGDKVTDMPPGFKLMASTPSCAI
AGMADEARGYYAVQFHPEVTHTVQGRAMLTRFVREICGCRGDWVMGDYIAEAVQSIRAQVGDEEVILGLSGGVDSSVAAA
LIHRAIGDHLTCVFVDHGLLRLNEGDLVMDMFAGKLHAKVIRVDASELFLGQLAGVTDPEKKRKIIGGLFVDVFKAEAAK
LKGDGAKGAKWLAQGTIYPDVIESGGAKSKKAVTIKSHHNVGGLPEQLGLKLLEPLRELFKDEVRELGVALGLPPDMVYR
HPFPGPGLGVRILGEVKKEYADLLRRADAIFIEELRSTLDPDSGKSWYELTSQAFTVFLPVKSVGVMGDGRTYDYVVALR
AVQTSDFMTADWAELPYALLKKVSSRIINEVRGINRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-116 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-116 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-116 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-100 48