Gene Information

Name : cadA1 (THI_1995)
Accession : YP_003624480.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Resistance
Product : Cadmium-transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.3
Position : 1958122 - 1960437 bp
Length : 2316 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 10660539, 10858330, 11282588, 9339465; Product type t : transporter

DNA sequence :
ATGAGCCAGTACGACCCCACCAGCACAGCGTTACGCCTGCCTGTCCAGGCGCAAGACCATGAACCCGCCTGTGACCACGA
TCATGGTCACGACCGCGGCCCTGATGCACATACCCACGCCCACGCGGCGGCCGATGCCTGCTGCGCCCCAACGACACAGA
CCGACTGCCTCACGGGGGTGTGCAACACCAATCCGGCACCCGAAGGGACCAGCCGGGTGCGCTACCGCATCGACAAGATG
GACTGCCCGACCGAGGAGCGCCTGATCCGCAACAAGCTGGAGGCCATGCCCGGGGTTGTGCAGCTCGACTTCAACCTCGT
GAATCGGGAGCTCACGGTGTATCACCGCTTGGATCAGCCCCAGGAGATTGCCGTGGCGCTGGACAAGCTGGGCATGGCAC
CCAATTTGCTGGAAGCCAATGCGCCGGTGTCCGTGCTTCCCCCCGCCCTGAGCCGAAGGCAAAAAGGTCTGCTCGCCGTG
GCTGGCGCCGCCGCCGTCGCGGCCGAGGTCATCGCCTGGTCGAGCGGGCAAGAAGCCTCGTGGATGGTGATGGCGCTTGC
CGCCGTGTCCATCCTCAGCGCCGGTCTGCCGACCCTCAAGAAGGGCTGGATCGCGCTCAGAAACCTGACCCTCAATATCA
ACTTCCTGATGTCCATCGCCGTGGCCGGGGCCGTGGCGCTCGGCAAGTGGCCGGAAGCGGCGATGGTGGTGTTCCTGTTC
GCCGTGGCCGAGGCGATCGAGGCGCTGTCGCTGGAGCGTGCCCGCAACGCGATCAAGGCGCTCACGGCCATCGCGCCGGA
AACCGCCGAGGTCAAGGCCGGCGAGGCCTGGCAGACCAAGCCGGTGGCCGGGGTGGCGGTCGGCAGCCGCATCCGGGTGC
GCACCGGCGCGCGGGTGCCGCTGGACGCACGCGTCGACTCCGGCCGCGCGGCGCTGAACCAGGCGCCGATCACCGGGGAA
AGCCTGCCCGTGGACAAGCAAGCGGGTGACCTGCTGTATGCCGGCAGCATCGTGGCCGATGGCGTGGTGGAAGCCACCGT
CACGGCCTCGGCTGGTGACAGCACCTTGGCCCGCATCGCCCTGGCCATCCAGAGCGCGCAGTCACAGCGCGCGCCGACCC
AGCGTTTCGTCGATCAATTCGCGCGCTACTACACCCCCGCGGTGGTGGTCTTCGCCATCGCCGTGGCCATCCTCGGCCCG
CTGCTGAGCGGCGGCGGCTGGAGTTCCTGGCTGTACGAGGCCCTGGTCATGCTGGTCATCGCCTGCCCCTGCGCCTTGGT
GGTGTCGACCCCGGTCACGGTGGTCAGCGGCCTCGCGGCGGCGGCCCGGAGGGGCATCCTCATCAAGGGCGGGGTGCATC
TCGAAGGCGGCCGGCTGCTCAAAGCCGTGGCGCTCGACAAGACCGGCACGCTGACCCTCGGCAAGCCCGCGCTGACCGAT
GCGATCCCGCTTGGCGATATGCCGATCGCGCAAGCCCTGCGGATCGCCGCCAGCCTCGATGACCACAGCACCCATCCGGT
CGCCCAGGCGCTGGTCGCCGGTTGGCGCGCGCAGCAGCCGGGCGCCGCAGTCATGCCTGTCGATGATTTCGGCGTGCTCC
AGGGGCGCGGCGTCACAGGCCGTATTGCCGGTCAGGATTGGCATCTGGGCAATCACCGTCTGGTCGAAGAGATCGGGGGG
TGTTCGGCGGCACTGGAGGCGCGGCTTGCTGTCCTGGAAAATGCCGGCAAAACCGCCATCGTTCTGTGTGACGCGGCCGA
TCCGGTGGCCGTGTTTGGCGTTGCCGACACCCTGAGGCCGGAGAGCGCGCGGGCCGTTGCATCCCTCAAGTCGCTGCATG
TCGAACCGGTCATGTTGACCGGCGACAACCCGGCCACGGCACGGGCGATTGCCGTTCAGCTCGGCATCAAGGATGCTCGC
GGCAATCTGCTGCCGCAGGACAAGCAAGCCGCTGTCGCGGAGCTTCTTGGGCGCTACGGGTCGGTCGGCATGGTCGGCGA
CGGAGTGAACGATGCGCCGGCGCTGGCGCGTGCGACGATCGGCTTCGCCATGGGGGCGGCCGGCACCGCCACGGCGCTGG
AGACCGCCGATGTGGCCATCATGGACGACGACCCGCGCAAGATCGCCGATTTCATCCGCTTGAGCCGGCGCACCGCCGCG
ATCCTCAAGCAGAACATCACCCTCGCGCTGGGCATCAAGGCGGTGTTCTTCGCCTTGGCCCTGAGCGGAGTGGCGACCCT
GTGGATGGCGGTGTTCGCCGACATGGGGGCCAGCCTTCTGGTGGTGTTCAACGGGATGCGACTGCTGCGCCGGTGA

Protein sequence :
MSQYDPTSTALRLPVQAQDHEPACDHDHGHDRGPDAHTHAHAAADACCAPTTQTDCLTGVCNTNPAPEGTSRVRYRIDKM
DCPTEERLIRNKLEAMPGVVQLDFNLVNRELTVYHRLDQPQEIAVALDKLGMAPNLLEANAPVSVLPPALSRRQKGLLAV
AGAAAVAAEVIAWSSGQEASWMVMALAAVSILSAGLPTLKKGWIALRNLTLNINFLMSIAVAGAVALGKWPEAAMVVFLF
AVAEAIEALSLERARNAIKALTAIAPETAEVKAGEAWQTKPVAGVAVGSRIRVRTGARVPLDARVDSGRAALNQAPITGE
SLPVDKQAGDLLYAGSIVADGVVEATVTASAGDSTLARIALAIQSAQSQRAPTQRFVDQFARYYTPAVVVFAIAVAILGP
LLSGGGWSSWLYEALVMLVIACPCALVVSTPVTVVSGLAAAARRGILIKGGVHLEGGRLLKAVALDKTGTLTLGKPALTD
AIPLGDMPIAQALRIAASLDDHSTHPVAQALVAGWRAQQPGAAVMPVDDFGVLQGRGVTGRIAGQDWHLGNHRLVEEIGG
CSAALEARLAVLENAGKTAIVLCDAADPVAVFGVADTLRPESARAVASLKSLHVEPVMLTGDNPATARAIAVQLGIKDAR
GNLLPQDKQAAVAELLGRYGSVGMVGDGVNDAPALARATIGFAMGAAGTATALETADVAIMDDDPRKIADFIRLSRRTAA
ILKQNITLALGIKAVFFALALSGVATLWMAVFADMGASLLVVFNGMRLLRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 4e-160 61
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-97 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA1 YP_003624480.1 Cadmium-transporting ATPase BAC0298 Protein 1e-153 59