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Name : merA1 (THI_1799) Accession : YP_003624297.1 Strain : Thiomonas sp. 3As Genome accession: NC_014145 Putative virulence/resistance : Resistance Product : Mercuric reductase (Hg(II) reductase) Function : - COG functional category : - COG ID : - EC number : 1.16.1.1 Position : 1786551 - 1788221 bp Length : 1671 bp Strand : - Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6530603, 8063107; Product type e : enzyme DNA sequence : ATGGAAATCCTGAGCATCAGCGGCATGACCTGCAACGCCTGCGCTACCCACGTCAAACACGCCCTGGAAAAGCTACCCGG CGTGAAGTCCGCGCAGGTGTCGTACCCGCTGGGGACGGCCGAAGTCGTGGCCGATGACAGCATCTCGTTCGACGCGATGG CTGCGGCCGTGGCCAAGGCGGGCTACGCGGCGAAGCAGGCGGATCGTGCGCCGACGCCGTCGTACGGTTCAACCGACTCG GCCCGTTCTACCCATCCTGCCCGCGGTGACGCCAGCGATCTGCGCATCGCCGTCATCGGCAGCGGCGGCGCGGCCATGGC GGCGGCGATCAAGGCGGCCGACAGCGGCGCGCGCGTCACGCTGATCGAACGCGGGGTGATCGGCGGCACTTGCGTCAACG TCGGCTGTGTGCCGTCCAAGATCATGATCCGCGCCGCGCACATCGCCCAGTTGCGCCGCCGCAGCCCGTTCGACGCGGGC ATCCCACCCACCTCCCCCGCCATCCTGCGCGACAAACTGCTCGCCCAGCAGCAGGCGCGGGTGGACGAGCTGCGCCACGC CAAATATGAAAGCATCATCGAGGGTCAGCCCGCCATCGCCACCCTGCACGGCACCGCCCGGTTCCAGGACGACCGAACGC TGGCCGTGACCCTGCACGACGGCAGCTCACGCCAGGTGAGCTTCGATCGCTGCCTTATCGCCACCGGCGCCAGTCCGTCC ATTCCTCCGATTGCGGGACTGAAGGGCACGCCGTACTGGACGTCGACCGAGGCGCTGGAGGCCGATACCATTCCGCCGCG CCTGGCGGTCATCGGCTCTTCTGTCGTCGCGCTGGAGCTGGCCCAGGCCTACTCCCGCCTGGGCAGCCAGGTCACCCTGA TCGCGCGCAACACCCTGCTGTCGCGCGACGATCCGGCCATCGGCGAGGCGTTGACCGCCGCACTGCGCGAAGAGGGCCTC ACCGTGCTGACTCACGCCCAGGTCGGTGCGGTGGCCTACGCCGACGGCTGCTTCGCGCTGACCACGAACCAGGGCGAAAT CCGCGCCGAGCGCCTGCTGGTGGCCACGGGCCGCGCGCCCAACACCGCGGCGCTCGATCTGCACGCTGCAGGCGTGCATT GCGATGCGCACGGCGCCATCGTGGTCGATGACCATTTGCGCACCAATGTGCCGCACATTTACGCCGCGGGCGACTGCACC GATCAGCCGCAATTCGTCTATGTGGCCGCAGCCGGGGGCACGCGTGCGGCCATCAACATGACCGGCGGCGAGGCGACGCT CGACCTCTCGGCCATGCCGGCCGTGGTGTTCACCGACCCGCAAGTGGCCACGGTGGGGCTGAGCGAGGCGCAGGCGCAGC GACAAGGCATCCAGACCGACAGCCGCACGCTGAGCCTGGACAACATCCCCCGCGCCCTGGCCAACTTCGACACGCGCGGC TTCATCAAGCTGGTCGCCGAGGCGCAAAGCGGGCGCCTGCTCGGCGTCCAGGCGGTGGCCGCCGAGGCAGGCGAACTCAT CCAGACGGCCGCGCTCGCCATTCGCAACCGCATGACGGTGCAGCAACTGGCCGACCAACTCTTCCCCTACTTGACCATGG TCGAAGGCCTGAAGCTGGCCGCCCAGACCTTCACCAAGGATGTGACGCAACTGTCATGCTGCGCGGGGTGA Protein sequence : MEILSISGMTCNACATHVKHALEKLPGVKSAQVSYPLGTAEVVADDSISFDAMAAAVAKAGYAAKQADRAPTPSYGSTDS ARSTHPARGDASDLRIAVIGSGGAAMAAAIKAADSGARVTLIERGVIGGTCVNVGCVPSKIMIRAAHIAQLRRRSPFDAG IPPTSPAILRDKLLAQQQARVDELRHAKYESIIEGQPAIATLHGTARFQDDRTLAVTLHDGSSRQVSFDRCLIATGASPS IPPIAGLKGTPYWTSTEALEADTIPPRLAVIGSSVVALELAQAYSRLGSQVTLIARNTLLSRDDPAIGEALTAALREEGL TVLTHAQVGAVAYADGCFALTTNQGEIRAERLLVATGRAPNTAALDLHAAGVHCDAHGAIVVDDHLRTNVPHIYAAGDCT DQPQFVYVAAAGGTRAAINMTGGEATLDLSAMPAVVFTDPQVATVGLSEAQAQRQGIQTDSRTLSLDNIPRALANFDTRG FIKLVAEAQSGRLLGVQAVAAEAGELIQTAALAIRNRMTVQQLADQLFPYLTMVEGLKLAAQTFTKDVTQLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 4e-173 | 71 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 7e-172 | 71 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 7e-172 | 71 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 4e-173 | 71 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 4e-173 | 71 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 9e-172 | 71 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 1e-175 | 71 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 5e-176 | 71 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 3e-170 | 70 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 2e-167 | 68 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 9e-87 | 43 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 1e-86 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| merA1 | YP_003624297.1 | Mercuric reductase (Hg(II) reductase) | BAC0652 | Protein | 9e-170 | 70 |
| merA1 | YP_003624297.1 | Mercuric reductase (Hg(II) reductase) | BAC0653 | Protein | 1e-169 | 70 |
| merA1 | YP_003624297.1 | Mercuric reductase (Hg(II) reductase) | BAC0650 | Protein | 2e-163 | 65 |
| merA1 | YP_003624297.1 | Mercuric reductase (Hg(II) reductase) | BAC0224 | Protein | 1e-86 | 45 |
| merA1 | YP_003624297.1 | Mercuric reductase (Hg(II) reductase) | BAC0651 | Protein | 6e-87 | 43 |
