Gene Information

Name : vipA (THI_1624)
Accession : YP_003624136.1
Strain : Thiomonas sp. 3As
Genome accession: NC_014145
Putative virulence/resistance : Virulence
Product : Vi polysaccharide biosynthesis protein; putative UDP-glucose 6-dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.22
Position : 1614347 - 1615627 bp
Length : 1281 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8248629, 8331073; Product type e : enzyme

DNA sequence : 
ATGACAGTAGTTGCTGTGGTGGGATTGGGGTATGTCGGTCTTCCTTTGGCCGTCGAGTTTGGTAAAAAATATCGCACGAT
CGGATTCGACCTCTCGGTCGAAAAAATAGCGGCTTATTGCAAGCATGTCGATCCGACTGGGGAAGTCAGTCAGGAGAGCC
TCAAGCAGGCGACCTTGCTCGAGCCGACAACCGATGCTTCGAAACTGAAAGAGGCCGACTTTGTGATCGTCGCCGTGCCA
ACGCCGGTTGACGATGCCCACAACCCGGATTTCAGCCCCCTCGTGGGCGCTAGCACCTCCGTTGGCAAATATCTCAAACC
CGGCGCCATCGTGGTCTATGAATCGACCGTTTATCCTGGGGCTACCGAAGAAATCTGTGTGCCGATTCTTGAAAAACAGT
CGGGGCTGAAGTGGAAAAAAGATTTCTTCGTCGGCTATTCACCCGAGCGTATCAATCCAGGCGACAAAGAGCACACCCTG
ACCCGAATTGTCAAGGTGGTTTCTGGAGATACCCCGGAGACGCTTGAAACCGTCGCAAATGTTTATGCCTCGGTGATTAC
GGCCGGGGTTCACCGAGCCGAAAGCATCAAAGTGGCCGAGGCGGCGAAAGTGATTGAAAACACGCAGCGCGACCTGAATA
TTGCGCTGATGAATGAGTTGTCGCTCATTTTTCATCGCATTGGCATTGATACGCTGGACGTGCTCAAGGCGGCGGGTACC
AAGTGGAATTTCCTGCCGTTTCGTCCGGGCCTGGTGGGTGGGCATTGCATCGGTGTCGATCCTTATTACCTCACGCACAA
GGCCGACATGCTCGGCTATCACCCGCAAGTGATTCTGGCGGGGCGTCGCATCAATGACGGTATGGGCAAATACATCGCTG
AACAGACGATCAAGCAAATGAGTCAGGCGGGCCTGCCGATCAAGGGGAGCGACGTGATCGTTCTCGGTCTGACCTTCAAG
GAAAACTGCCCCGATCTGCGCAATTCCAAGGTGATCGACGTGATTCGCGAACTGGCGTCATATGGGGTCAACGTGATCGT
GCACGACCCCATTGCCGATGCGGACGAGGCTGTGCATGAATATGGCGTCACGCTCACGCCTTGGGCCGAATTGCCTCGCG
CTCAGGCCATCGTGGCGGCCGTGGCGCACCAAGCCTACAAGGACATGTCGGTCGCCGAAACTCTCGAAAAGCTGCTGCCG
TCTGGCATTTTCATGGACATCAAGTGCCAATACGACGCTGCCGCGCTCCAGTCGCACGGTGCCCAGGTCTGGAGACTTTG
A

Protein sequence : 
MTVVAVVGLGYVGLPLAVEFGKKYRTIGFDLSVEKIAAYCKHVDPTGEVSQESLKQATLLEPTTDASKLKEADFVIVAVP
TPVDDAHNPDFSPLVGASTSVGKYLKPGAIVVYESTVYPGATEEICVPILEKQSGLKWKKDFFVGYSPERINPGDKEHTL
TRIVKVVSGDTPETLETVANVYASVITAGVHRAESIKVAEAAKVIENTQRDLNIALMNELSLIFHRIGIDTLDVLKAAGT
KWNFLPFRPGLVGGHCIGVDPYYLTHKADMLGYHPQVILAGRRINDGMGKYIAEQTIKQMSQAGLPIKGSDVIVLGLTFK
ENCPDLRNSKVIDVIRELASYGVNVIVHDPIADADEAVHEYGVTLTPWAELPRAQAIVAAVAHQAYKDMSVAETLEKLLP
SGIFMDIKCQYDAAALQSHGAQVWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 8e-106 59
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-96 58
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 2e-96 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vipA YP_003624136.1 Vi polysaccharide biosynthesis protein; putative UDP-glucose 6-dehydrogenase VFG0431 Protein 9e-97 58