Gene Information

Name : virB4 (THI_p0055)
Accession : YP_003622622.1
Strain :
Genome accession: NC_014144
Putative virulence/resistance : Virulence
Product : Type IV secretory pathway, VirB4 component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 37672 - 40086 bp
Length : 2415 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 3281947; Product type t : transporter

DNA sequence :
ATGTCCACCACGGCAACACTGATTGAAAAAACCAAGTCCGAAAGCGAGCTGGCGGGGTTCATCCCCTATCGCACGCAACT
GACGCCCGCCATTGTTCGGCTGCAAAGCGGCGAATACTGCTTCACGTTCAAGATGGCGGGGGCGGCGCATGAAAGCGCCG
ACACGAGCACGATCAATGGATGGCACCGGCAATTTGCGCAACTGCTGCGCAACATTGCCGACACCCACATCGCTGTGTGG
ACGCATACAGTACGCATCAAATACAACGCATACCCGGACGGCGAGCCGACCAATGGTTTCGGCATCGACCTCAACGCGAA
ATACCGCCAGCGGTTTCAGCAAGATGAGAAGTTCGTCAACGAGCTTTACATCACCGTGCTTTTTAAGCCCCAGCGACTGG
ATGCCAAAGGGCTATTCGATGGCCTGATGAGAAAGCCCCGCACCGATGCGGAAATCAAAGACGATTTGGGCACGGTAGAA
GAACTGATCCGCACGGTCGGCACTTCGCTCTATAACTATGGCCCGGAATTGCTCAAGGTCTATGAGAAAAACGGCGTTCT
GTTCAGCGAGCAGCTTGAGTTTTATGCCTATCTGTTCGATGGTGAGCATCACCCCTTCCCGGTGCCGCGTGCCGACATCA
ATGAGGTGTTCGGCATCACGCGCCCGCTATTCGGCGCAGGCGGTCTGATTGCCCTCAAGGGGCCGATCAAAACGCAGATG
GCCGCTGCCATCACCATCCGGGAATATCCACGGCCTACCGCGCCGGGCCTGCTCAACGAATTGTTAGGCATGCCTTTCGA
GCTGGTTCTGAGCCAATCTTTCACCTTCATCGAAAAACAAACGGCGGTACAGCGCATGAGCCGCCAGCATGGCCGCATGG
TCAATGCGGGTGATCTGGCGCAGAGCCAAGTTGACGAAATCGGTGACGCCCTGGATCAGCTCATGTCCAATGCGTTTGTG
ATGGGCACCCACAGCCTCACGCTGTTGGTCAAATCGCCCACGCGCAAGGGCGTGGATACCGCTGTGGCCCTCGCTGGCAC
GGCGCTGGCCGATGTGGGTATGAAGTGGGCGCGAGAGGACATTGCGACCCCCGCCGCGTATTTCTCGCAACTGCCCGGCA
ACTACAAATATCGCCCCCGTCTGGCGGACATCACCAGCCTGAATTTTGCGGGCTTTGCCTCAAACCACAATTTCCCGATT
GGACGCATCAAGGGCGCGCAGTGGGGGGATGCGGTGATGGCCTTCAAGACCACCTCGGGCGCACCGTATTACTTCAATTT
TCACGCGGTTGATCCGACGCAGGCCGTCGCCGATCCGAACCACCGGGAACCGGCGAACACCGTTGTGATGGGTAAGACCG
GCACGGGCAAAACCGTGCTGGCGGGGATGCTTCTGGCGATGGTGAGCAAGTTCAACGTGCCTGGCAAGCGGTTTACTGCG
GTGGTGTTCGACAAAGACCTCGGGATGTCGGTGGCGACCCGCGCGATGGGCGGGCGTTACTACCCGATCAAGCGCGGTGA
ACCCTCGGGATTCAACCCCTTTCAGCTCCCGGCCACGCAAGCCACGCAGATGTTTCTGGAAAAGCTGGTCAAGGTGTTGG
TGCGCAGCGAGGCGCACCCCTTCACCACGGTTCAGGAAAGCGAAATCAGCAATGCAATTCGCGGGGTGATGTCAGCGCCC
AAGCCCTTGCGGCGGCTGGGCGCGATGATGGAATTTCTCGATCCGACCGACCCGAACGGTATCCGCCCCCGCCTGCAGCG
TTGGTGCGGCACGGGCACCCTGGCCTGGCTGTTCGACAACGATGAGGACACCATTGATGTCGATAACACGCCGATCATTG
GCTTCGATGTCACCGAGTTTCTGGACGAGCCCGAGATTCGCACCCCGACGATTCTCTACCTGTTCCACCGTATTGAAAGC
CTGATCGACGGGCGGCGCATCCCGATTTTCATTGACGAGTTTCCGAAGGTGCTCGGCGATGAGGCATTCCGCGACCTGAT
CGAAAACAAGCTGGTGACGATCCGAAAGCAAGATGGTTTTCTGGTGATGTTCTCACAAAGCCCGGAGCAACTGATGCGCA
GCCCGATTGCGTATGCGCTGGTCGGGCAGACCTCGACCAAGATTTTTCTGCCGAATCCGCAGGCGGATCGCAAGAGCTAC
ATCGAGGATTTCAAGCTGTCCGAAAAAGAATACAGCCTCATCAAGAATTTGGGCGAGAAGTCCCGCCAGTTCCTCATTAA
ACAAGGGGATGGTTCGGTTGTCGCTGAAATGAATCTGGCCGGGATGCACGATGAAATCGCTGTGCTCTCCGGCAATACAG
AAACCTCACACCTGGTTGAACGCCTTGTCAAAGAACATGGCAATAACCCGGAAATCTGGCTTCCCGAGTTTCACCGCATC
CGTCAAGGAGTATGA

Protein sequence :
MSTTATLIEKTKSESELAGFIPYRTQLTPAIVRLQSGEYCFTFKMAGAAHESADTSTINGWHRQFAQLLRNIADTHIAVW
THTVRIKYNAYPDGEPTNGFGIDLNAKYRQRFQQDEKFVNELYITVLFKPQRLDAKGLFDGLMRKPRTDAEIKDDLGTVE
ELIRTVGTSLYNYGPELLKVYEKNGVLFSEQLEFYAYLFDGEHHPFPVPRADINEVFGITRPLFGAGGLIALKGPIKTQM
AAAITIREYPRPTAPGLLNELLGMPFELVLSQSFTFIEKQTAVQRMSRQHGRMVNAGDLAQSQVDEIGDALDQLMSNAFV
MGTHSLTLLVKSPTRKGVDTAVALAGTALADVGMKWAREDIATPAAYFSQLPGNYKYRPRLADITSLNFAGFASNHNFPI
GRIKGAQWGDAVMAFKTTSGAPYYFNFHAVDPTQAVADPNHREPANTVVMGKTGTGKTVLAGMLLAMVSKFNVPGKRFTA
VVFDKDLGMSVATRAMGGRYYPIKRGEPSGFNPFQLPATQATQMFLEKLVKVLVRSEAHPFTTVQESEISNAIRGVMSAP
KPLRRLGAMMEFLDPTDPNGIRPRLQRWCGTGTLAWLFDNDEDTIDVDNTPIIGFDVTEFLDEPEIRTPTILYLFHRIES
LIDGRRIPIFIDEFPKVLGDEAFRDLIENKLVTIRKQDGFLVMFSQSPEQLMRSPIAYALVGQTSTKIFLPNPQADRKSY
IEDFKLSEKEYSLIKNLGEKSRQFLIKQGDGSVVAEMNLAGMHDEIAVLSGNTETSHLVERLVKEHGNNPEIWLPEFHRI
RQGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trwK YP_001610476.1 TrwK protein Virulence Not named Protein 2e-137 42
trwK CAD42844.1 TrwK protein Not tested trw-PAI Protein 2e-137 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
virB4 YP_003622622.1 Type IV secretory pathway, VirB4 component VFG2259 Protein 3e-139 42