Gene Information

Name : guaA (LKI_02000)
Accession : YP_003620912.1
Strain : Leuconostoc kimchii IMSNU 11154
Genome accession: NC_014136
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 371685 - 373232 bp
Length : 1548 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGGCTGAAGTAAATGCCGATAAAGTCCTGGTATTGGACTACGGTAGTCAATATAACCAATTAATTACCCGCCGAATACG
TGAGATGGGTGTTTTTTCAGAGCTGAAGTCTCGCAATATGACAATAGCGGAAATTAAAGCGTATAATCCTAAAGCAATTA
TTCTGTCTGGCGGTCCAATGTCTGTATATGAAGCAAATGCTTTTACAGTGGATAAGGCTATCTTTGATCTTGGTCTACCA
ATTCTTGGTGTGTGCTACGGTATGCAATTAATGGCACAAACCTTAGGTGGAAAAGTCGAAGCTAATCCTGGCAATGGTGA
GTTTGGACAAACAATTTTGCATCAAAAGCAAAAATCTGGGTTGTTACTTGCAAATACACCAGATTCTCAAACGGTTTTGA
TGAGTCACTCAGATAATGTCGTGAACTTACCGGATGGCTTTGTGGTGGCTGGTGGTTCTGATGCAACACCGATTGCTGCC
ATTGCTGATGATCAACGGCGATTGTATGGTGTACAATTTCATGCGGAAACGACACTTTCTGAACATGGTCAACAAATTTT
GCACAATTTCGTTTTCGATATTGCGCATGCTGAAGCTAATTGGGATATGAGTGGGTTTATAGATGAACAAATAGCGCATA
TTCGTGAGGTTGTTGGTGATAAAAAAGTTTTGTTAGGTCTTTCTGGCGGTGTTGATTCATCAGTTGTTGGTGTTTTATTG
CATAAAGCCATAGGAAGCCAACTAACATCTATTTTTGTTGATCATGGCTTGTTGCGTAAAAATGAAGCTGAACAAGTTAT
GGAAATGATGGGGCAACAGTTTGGTTTGAATATTATCAAAGTGGATGCCCAAGAACGCTTTTTGTCAAAATTGGCAGGTA
TCACAGATCCCGAACAAAAGCGTAAAATCATTGGTAATGAATTTATTCAAGTGTTCAATGATGAAGCAACAAAGTTGGAT
GGTATTGAGTTCTTAGCACAAGGCACTTTATATACTGATGTGATTGAGTCAGGAACAGATACTGCTCAAACAATTAAATC
ACATCATAATGTTGGGGGCTTACCAGAAGACTTACAATTTAAGTTAATCGAGCCACTTAATACGTTATTCAAAGATGAGG
TACGTGAACTTGGTGAAGCACTCGATATGCCTCATGAAATGGTTTGGCGACAACCATTTCCAGGCCCTGGGTTAGGCATT
CGTATATTGGGCGATATTACAGAAGATAAGCTCGAAATTGTACGAGATTCTGATTGGATTTTGCGTGATGAAATTTCAAA
AGCTGGTCTCGAAGCTGATGTTTGGCAGTATTTTACTGTTTTAACTGGTGTTCGTTCAGTGGGCGTCATGGGTGATTATC
GTACCTATGATTATACAATTGCTATAAGAGCGATTACTTCAGTTGATGGCATGACGGCTGACTTTGCGCAGCTACCTTGG
CCATTGCTCCAGAAAATTTCAGCACGTATTGTTAATGAGGTTGGACATATTAACCGCGTGGTCTATGATATTACTGCTAA
GCCACCAGCTACGGTTGAATGGGAATAA

Protein sequence :
MAEVNADKVLVLDYGSQYNQLITRRIREMGVFSELKSRNMTIAEIKAYNPKAIILSGGPMSVYEANAFTVDKAIFDLGLP
ILGVCYGMQLMAQTLGGKVEANPGNGEFGQTILHQKQKSGLLLANTPDSQTVLMSHSDNVVNLPDGFVVAGGSDATPIAA
IADDQRRLYGVQFHAETTLSEHGQQILHNFVFDIAHAEANWDMSGFIDEQIAHIREVVGDKKVLLGLSGGVDSSVVGVLL
HKAIGSQLTSIFVDHGLLRKNEAEQVMEMMGQQFGLNIIKVDAQERFLSKLAGITDPEQKRKIIGNEFIQVFNDEATKLD
GIEFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDLQFKLIEPLNTLFKDEVRELGEALDMPHEMVWRQPFPGPGLGI
RILGDITEDKLEIVRDSDWILRDEISKAGLEADVWQYFTVLTGVRSVGVMGDYRTYDYTIAIRAITSVDGMTADFAQLPW
PLLQKISARIVNEVGHINRVVYDITAKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-161 65
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-162 65
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-162 65
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-119 50